{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T07:25:29Z","timestamp":1760081129542},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T00:00:00Z","timestamp":1669334400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hepatology Research"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the usefulness and safety of a newly developed full\u2010core biopsy needle.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We selected 149 patients who underwent percutaneous liver biopsy at our institution from February 2019 to April 2021. We excluded 35 patients with hepatic fibrosis stage F3 or higher, which made it histopathologically difficult to measure the number of complete portal triads. The patients were divided into two groups as follows: 62 cases with the 18\u2010G conventional automated needle (TruCore needle: T needle), and 52 cases with the 18\u2010G full\u2010core needle (CorVocet needle: C needle). We measured the number of complete portal triads in the liver tissue specimens, and the sum of the length and width of the collected tissues. Moreover, we compared the number of session counts, fragmentations, and complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The sum of the length and the width was 12.8\u00a0mm (11.2\u201314.3) and 15.9\u00a0mm (13.1\u201317.3; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), and 0.68\u00a0mm (0.63\u20130.74) and 0.82\u00a0mm (0.78\u20130.90; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) for the T needle and C needle, respectively. The number of complete portal triads and fragmentation was six (3\u20138) and 10 (6\u201313; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), and one (1\u201310) and one (1\u20133; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), for the T needle and C needle, respectively. There was one session count (1\u20132) in both groups; however, there were significantly higher cases of two sessions with the T needle than that with the C needle (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.018). There were no serious adverse events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Compared with the conventional needles, the newly developed full\u2010core needles enabled the acquisition of a larger amount of tissue sample in liver biopsy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hepr.13856","type":"journal-article","created":{"date-parts":[[2022,11,10]],"date-time":"2022-11-10T18:11:57Z","timestamp":1668103917000},"page":"247-257","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The usefulness of a newly developed full\u2010core biopsy needle in liver biopsy"],"prefix":"10.1111","volume":"53","author":[{"given":"Hirohito","family":"Takeuchi","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Tokyo Medical University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsutoshi","family":"Sugimoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Tokyo Medical University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Kakegawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Tokyo Medical University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Tomita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Tokyo Medical University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Tokyo Medical University  Tokyo 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