{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T16:30:27Z","timestamp":1782837027038,"version":"3.54.5"},"reference-count":44,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T00:00:00Z","timestamp":1707782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hepatology Research"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed to establish the shear wave measurement (SWM) cut\u2010off value for each fibrosis stage using magnetic resonance (MR) elastography values as a reference standard.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We prospectively analyzed 594 patients with chronic liver disease who underwent SWM and MR elastography. Correlation coefficients (were analyzed, and the diagnostic value was evaluated by the area under the receiver operating characteristic curve. Liver stiffness was categorized by MR elastography as F0 (&lt;2.61\u00a0kPa), F1 (\u22652.61\u00a0kPa, &lt;2.97\u00a0kPa, any fibrosis), F2 (\u22652.97\u00a0kPa, &lt;3.62\u00a0kPa, significant fibrosis), F3 (\u22653.62\u00a0kPa, &lt;4.62\u00a0kPa, advanced fibrosis), or F4 (\u22654.62\u00a0kPa, cirrhosis).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median SWM values increased significantly with increasing fibrosis stage (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001). The correlation coefficient between SWM and MR elastography values was 0.793 (95% confidence interval 0.761\u20130.821). The correlation coefficients between SWM and MR elastography values significantly decreased with increasing body mass index and skin\u2013capsular distance; skin\u2013capsular distance values were associated with significant differences in sensitivity, specificity, accuracy, or positive predictive value, whereas body mass index values were not. The best cut\u2010off values for any fibrosis, significant fibrosis, advanced fibrosis, and cirrhosis were 6.18, 7.09, 8.05, and 10.89\u00a0kPa, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This multicenter study in a large number of patients established SWM cut\u2010off values for different degrees of fibrosis in chronic liver diseases using MR elastography as a reference standard. It is expected that these cut\u2010off values will be applied to liver diseases in the future.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hepr.14026","type":"journal-article","created":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T17:39:45Z","timestamp":1707845985000},"page":"851-858","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Diagnostic performance of shear wave measurement in the detection of hepatic fibrosis: A multicenter prospective study"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2211-495X","authenticated-orcid":false,"given":"Takashi","family":"Kumada","sequence":"first","affiliation":[{"name":"Department of Nursing Faculty of Nursing Gifu Kyoritsu University  Ogaki 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