{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T04:21:47Z","timestamp":1772252507507,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T00:00:00Z","timestamp":1714780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2022\u2010ER0906\u201000"],"award-info":[{"award-number":["2022\u2010ER0906\u201000"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hepatology Research"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>We aimed to explore the extent to which individuals previously diagnosed with nonalcoholic fatty liver disease (NAFLD) meet the criteria fulfilled with the new nomenclature, metabolic dysfunction\u2010associated steatotic liver disease (MASLD), within an Asian primary clinic cohort. Additionally, we assessed the reliability of the diagnostic performance of FIB\u20104 and NAFLD fibrosis score (NFS) for MASLD within the primary clinic cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective cross\u2010sectional study included participants who underwent magnetic resonance elastography and abdominal ultrasonography during their health checkups at nationwide health promotion centers (<jats:italic>n<\/jats:italic>\u00a0=\u00a06740).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence rates of NAFLD and MASLD diagnosed based on ultrasonography results were 36.7% and 38.0%, respectively. Notably, 96.8% of patients in the NAFLD cohort fulfilled the new criteria for MASLD. A small proportion of patients with NAFLD (<jats:italic>n<\/jats:italic>\u00a0=\u00a080, 3.2%) did not meet the MASLD criteria. Additionally, 168 patients (6.6%) were newly added to the MASLD group. The areas under the receiver operating characteristic curves for diagnosing advanced hepatic fibrosis for FIB\u20104 (0.824 in NAFLD vs. 0.818 in MASLD, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.891) and NFS (0.803 in NAFLD vs. 0.781 in MASLD, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.618) were comparable between the MASLD and NAFLD groups. Furthermore, the sensitivity, specificity, positive predictive value, and negative predictive value of FIB\u20104 and NFS for advanced fibrosis in MASLD were also comparable to those in NAFLD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Most patients (96.8%) previously diagnosed with NAFLD fulfilled the new criteria for MASLD in an Asian primary clinic cohort. Diagnostic performance of FIB\u20104 in the MASLD cohort demonstrated satisfactory results.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hepr.14054","type":"journal-article","created":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T17:17:00Z","timestamp":1714843020000},"page":"1027-1034","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Diagnostic performances of Fibrosis\u20104 index and nonalcoholic fatty liver disease fibrosis score in metabolic dysfunction\u2010associated steatotic liver disease in Asian primary care clinics"],"prefix":"10.1111","volume":"54","author":[{"given":"Huiyul","family":"Park","sequence":"first","affiliation":[{"name":"Department of Family Medicine Myoungji Hospital Hanyang University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mimi","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology Hanyang University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye\u2010Lin","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Pharmacy Sahmyook University  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seon","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Health Promotion Research Institute  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eileen L.","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Hanyang University College of Medicine  Seoul Korea"},{"name":"Hanyang Institute of Bioscience and Biotechnology Hanyang University  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2875-6139","authenticated-orcid":false,"given":"Dae Won","family":"Jun","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Hanyang University College of Medicine  Seoul Korea"},{"name":"Hanyang Institute of Bioscience and Biotechnology Hanyang University  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aohep.2023.101133"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2023.0291"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2020.106175"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2022.0365"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.5009\/gnl230044"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40885\u2010023\u201000243\u20108"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889\u2010021\u201010450\u20103"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.51789\/cmsj.2021.1.e15"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29367"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000443344"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2021.0178"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1467\u2010789x.2002.00065.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.4093\/dmj.2011.35.6.561"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2016.453"},{"key":"e_1_2_10_16_1","volume-title":"General 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