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In Japan, comprehensive hepatitis measures are implemented for the testing and treatment of viral hepatitis, thus enabling the early diagnosis of liver cancer. Nevertheless, patients with decompensated cirrhosis and liver cancer often have unfavorable prognoses and require repetitive long\u2010term treatment. In fiscal year 2018, an integrated policy of medical expense subsidies and research was established in Japan that aimed to alleviate patients' financial burden and launch the clinical registry of advanced liver disease. Over time, updates to the eligibility for the subsidy increased access to patients and has led to an increased number of beneficiaries. Additionally, the accumulation of clinical data in the registry has revealed the treatment choices for these diseases. However, the disparities in efforts across prefectures have also become evident. Raising public awareness of the policy and tightening the multisector healthcare network are keys to success in supporting qualifying patients with advanced liver disease.<\/jats:p>","DOI":"10.1111\/hepr.14085","type":"journal-article","created":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T10:59:24Z","timestamp":1718449164000},"page":"745-752","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Integrated policy of medical expense subsidies and clinical registry for patients with liver cancer and decompensated cirrhosis in Japan"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3084-8419","authenticated-orcid":false,"given":"Yasue","family":"Takeuchi","sequence":"first","affiliation":[{"name":"Hepatitis Information Center The Research Center for Hepatitis and Immunology National Center for Global Health and Medicine  Ichikawa Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akinori","family":"Nozawa","sequence":"additional","affiliation":[{"name":"Hepatitis Prevention and Control Office Cancer and Disease Control Division Public Health Bureau Labor, and Welfare  Tokyo Japan"},{"name":"Department of Hepato\u2010Biliary\u2010Pancreatic Surgery Osaka Metropolitan University Graduate School of Medicine  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Yukimoto","sequence":"additional","affiliation":[{"name":"Hepatitis Prevention and Control Office Cancer and Disease Control Division Public Health Bureau Labor, and Welfare  Tokyo Japan"},{"name":"Departments of Gastroenterology and Metabology Ehime University Graduate School of Medicine  Toon Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Kitsuka","sequence":"additional","affiliation":[{"name":"Hepatitis Prevention and Control Office Cancer and Disease Control Division Public Health Bureau Labor, and Welfare  Tokyo Japan"},{"name":"Liver Center Saga University Hospital Faculty of Medicine Saga University  Saga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Tateishi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Graduate School of Medicine The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhiko","family":"Koike","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Graduate School of Medicine The University of Tokyo  Tokyo Japan"},{"name":"Kanto Central Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuyuki","family":"Okano","sequence":"additional","affiliation":[{"name":"Hepatitis Prevention and Control Office Cancer and Disease Control Division Public Health Bureau Labor, and Welfare  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuya","family":"Kanto","sequence":"additional","affiliation":[{"name":"Hepatitis Information Center The Research Center for Hepatitis and Immunology National Center for Global Health and Medicine  Ichikawa Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,15]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"World Health Organization.Hepatitis B fact sheet world health organization;2023. 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