{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T13:00:30Z","timestamp":1789563630701,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T00:00:00Z","timestamp":1672358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Expectations"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Scalp cooling (SC) aims to prevent chemotherapy\u2010induced alopecia. The goal of this systematic review is to tackle ethical, legal, organizational and social issues related to SC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A critical appraisal of the literature was carried out using a systematic review design. MEDLINE, Embase\u00a0and Web of Science databases were searched up until 2 June\u00a02021. Studies addressing these aspects in English or Spanish were considered. Representatives of both patient associations and professional scientific societies related to the topic participated in the design of the protocol and the review of the findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 17 studies were included. Articles were critically appraised using the MMAT and SANRA. Findings were organized into four categories: (1) ethical aspects focused on equal access, gender equity\u00a0and doctor\u2013patient communication supported by Patient Decision Aids (PtDAs); (2) patient perspective and acceptability; (3) professional perspective and acceptability; (4) organizational aspects focused on accessibility and feasibility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cancer patients' expectations when using SC need to be adjusted to reduce the potential distress associated with hair loss. PtDAs could help patients clarify their values and preferences regarding SC. Equal access to technology should be guaranteed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patient or Public Contribution<\/jats:title><jats:p>In this systematic review, the representatives of the patient associations (Ms. Mar\u00eda Luz Amador Mu\u00f1oz of the Spanish Association Against Cancer [AECC] and Ms. Catiana Martinez C\u00e1novas of the Spanish Breast Cancer Federation [FECMA]) participated in the review of the study protocol, as well as in the results, discussion\u00a0and conclusions, making their contributions. In the type of design of these studies (systematic reviews), it is not usual to have the direct participation of patients, but in this one, we have done so, as it is a systematic review that is part of a report of the Spanish Network of Health Technology Assessment Agencies (ETS).<\/jats:p><\/jats:sec>","DOI":"10.1111\/hex.13679","type":"journal-article","created":{"date-parts":[[2022,12,31]],"date-time":"2022-12-31T06:38:43Z","timestamp":1672468723000},"page":"567-578","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Ethical, legal, organizational and social issues related to the use of scalp cooling for the prevention of chemotherapy\u2010induced alopecia: A systematic review"],"prefix":"10.1111","volume":"26","author":[{"given":"Janet","family":"Delgado Rodr\u00edguez","sequence":"first","affiliation":[{"name":"Department of Philosophy University of Granada Granada Spain"},{"name":"The Spanish Network of 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