{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:37:32Z","timestamp":1790703452823,"version":"4.1.0"},"reference-count":65,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T00:00:00Z","timestamp":1686614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Expectations"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Despite various efforts to improve human papillomavirus\u00a0(HPV) vaccine coverage in France, it has always been lower than in most other high\u2010income countries. The health authorities launched in 2018 the national PrevHPV research programme to (1) co\u2010develop with stakeholders and (2) evaluate the impact of a multicomponent complex intervention aimed at improving HPV vaccine coverage amongst French adolescents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the development process of the PrevHPV intervention using the GUIDance for rEporting of intervention Development framework as a guide.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>To develop the intervention, we used findings from (1) published evidence on effective strategies to improve vaccination uptake and on theoretical frameworks of health behaviour change; (2) primary data on target populations' knowledge, beliefs, attitudes, preferences, behaviours\u00a0and practices as well as the facilitators and barriers to HPV vaccination collected as part of the PrevHPV Programme\u00a0and (3) the advice of working groups involving stakeholders in a participatory approach. We paid attention to developing an intervention that would maximise reach, adoption, implementation\u00a0and maintenance in real\u2010world contexts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We co\u2010developed three components: (1) adolescents' and parents' education and motivation using eHealth tools (web conferences, videos, and a serious video game) and participatory learning at school; (2) general practitioners' e\u2010learning training on HPV using motivational interviewing techniques and provision of a decision aid tool\u00a0and (3) easier access to vaccination through vaccination days organised on participating middle schools' premises to propose free of charge initiation of the HPV vaccination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We co\u2010developed a multicomponent intervention that addresses a range of barriers and enablers of HPV vaccination. The next step is to build on the results of its evaluation to refine it before scaling it up if proven efficient. If so, it will add to the small number of multicomponent interventions aimed at improving HPV vaccination worldwide.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patient or Public Contribution<\/jats:title><jats:p>The public (adolescents, their parents, school staff\u00a0and health professionals) participated in the needs assessment using a mixed methods approach. The public was also involved in the components' development process to generate ideas about potential activities\/tools, critically revise the successive versions of the tools\u00a0and provide advice about the intervention practicalities, feasibility\u00a0and maintenance.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hex.13778","type":"journal-article","created":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T04:48:38Z","timestamp":1686718118000},"page":"1843-1853","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Co\u2010development of a school\u2010based and primary care\u2010based multicomponent intervention to improve HPV vaccine coverage amongst French adolescents (the PrevHPV Study)"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0192-8447","authenticated-orcid":false,"given":"Aur\u00e9lie","family":"Bocquier","sequence":"first","affiliation":[{"name":"APEMAC Universit\u00e9 de Lorraine Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Bruel","sequence":"additional","affiliation":[{"name":"Department of General Practice, Jacques Lisfranc Faculty of Medicine Saint\u2010Etienne\u2010Lyon University Saint\u2010Etienne France"},{"name":"Health, Systemic, Process UR 4129 Research Unit, University Claude Bernard University of Lyon Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgane","family":"Michel","sequence":"additional","affiliation":[{"name":"ECEVE UMR 1123, Universit\u00e9 de Paris Cit\u00e9 Paris France"},{"name":"Assistance Publique\u2010H\u00f4pitaux de Paris, H\u00f4tel Dieu, URC Eco Ile\u2010de\u2010France\/H\u00f4pital Robert Debr\u00e9 Unit\u00e9 d'\u00e9pid\u00e9miologie clinique Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u2010Sophie","family":"Le Duc\u2010Banaszuk","sequence":"additional","affiliation":[{"name":"Centre R\u00e9gional de Coordination des D\u00e9pistages des cancers\u2010Pays de la Loire Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Bonnay","sequence":"additional","affiliation":[{"name":"APEMAC Universit\u00e9 de Lorraine Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Branchereau","sequence":"additional","affiliation":[{"name":"Centre R\u00e9gional de Coordination des D\u00e9pistages des cancers\u2010Pays de la Loire Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karine","family":"Chevreul","sequence":"additional","affiliation":[{"name":"ECEVE UMR 1123, Universit\u00e9 de Paris Cit\u00e9 Paris France"},{"name":"Assistance Publique\u2010H\u00f4pitaux de Paris, H\u00f4tel Dieu, URC Eco Ile\u2010de\u2010France\/H\u00f4pital Robert Debr\u00e9 Unit\u00e9 d'\u00e9pid\u00e9miologie clinique Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Chyderiotis","sequence":"additional","affiliation":[{"name":"Emerging Disease Epidemiology Unit, Institut Pasteur Universit\u00e9 Paris Cit\u00e9 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lie","family":"Gauchet","sequence":"additional","affiliation":[{"name":"LIP\/PC2S Universit\u00e9 Grenoble Alpes Grenoble France"},{"name":"LIP\/PC2S Universit\u00e9 Savoie Mont Blanc Chamb\u00e9ry France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Giraudeau","sequence":"additional","affiliation":[{"name":"SPHERE U1246, Universit\u00e9 de Tours, Universit\u00e9 de Nantes INSERM Tours France"},{"name":"INSERM CIC 1415 CHRU de Tours Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dragos\u2010Paul","family":"Hagiu","sequence":"additional","affiliation":[{"name":"Department of General Practice, Jacques Lisfranc Faculty of Medicine Saint\u2010Etienne\u2010Lyon University Saint\u2010Etienne France"},{"name":"CIC\u2010INSERM 1408, CHU de Saint\u2010Etienne France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith E.","family":"Mueller","sequence":"additional","affiliation":[{"name":"Emerging Disease Epidemiology Unit, Institut Pasteur Universit\u00e9 Paris Cit\u00e9 Paris France"},{"name":"Univ. Rennes, EHESP, CNRS, Inserm, Ar\u00e8nes \u2010 UMR 6051 RSMS (Recherche sur les Services et Management en Sant\u00e9) \u2010 U 1309 Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amandine","family":"Gagneux\u2010Brunon","sequence":"additional","affiliation":[{"name":"Centre International de Recherche en Infectiologie, Team GIMAP, Univ Lyon, Universit\u00e9 Jean Monnet, Universit\u00e9 Claude Bernard Lyon 1, Inserm, U1111, CNRS, UMR530, CIC INSERM 1408 Vaccinologie CHU de Saint\u2010Etienne Saint\u2010Etienne France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Thilly","sequence":"additional","affiliation":[{"name":"APEMAC Universit\u00e9 de Lorraine Nancy France"},{"name":"D\u00e9partement M\u00e9thodologie, Promotion, Investigation Universit\u00e9 de Lorraine, CHRU\u2010Nancy Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"PrevHPV Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,13]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"WHO. 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