{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T02:07:20Z","timestamp":1791425240419,"version":"4.3.3"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T00:00:00Z","timestamp":1743638400000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012068","name":"Health and Care Research Wales","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012068","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Expectations"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>HIV prevention methods, such as pre\u2010exposure prophylaxis (PrEP), have been a significant contributing factor to a global decline in HIV transmission. PrEP has been available through the NHS in Wales since 2017. However, access is exclusively via sexual health clinics, and those accessing PrEP do not reflect those being diagnosed with HIV. Widening access beyond sexual health clinics may be one approach to encourage more equitable uptake, and there is growing interest in offering PrEP services in community pharmacies. We, therefore, aimed to explore the acceptability of PrEP services being delivered through community pharmacies among prospective service users.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a qualitative interview study of people living in Wales who either (i) currently access, (ii) previously accessed or are (iii) considering accessing PrEP via a sexual health clinic. Participants were recruited via community networks, and interviews were conducted virtually. Our topic guide was informed by Levesque's conceptual framework of access to healthcare, and we used reflexive thematic analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We interviewed 24 participants and included data from 20 in the analysis. Four themes were generated: experiences of accessing PrEP via sexual health clinics, the prospect of PrEP access via community pharmacies, other community settings in which PrEP may be accessed and concerns around integrated healthcare and healthcare data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PrEP access via community pharmacy is likely to be an acceptable option for people. There are uncertainties surrounding what a PrEP service would look like in a community pharmacy setting, and this would need clarifying to prospective users to increase the salience of access.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patient and Public Contribution<\/jats:title><jats:p>A team\u2010based approach was taken for developing the topic guide and agreeing on the codes for this study. This included people with lived experience of accessing PrEP in Wales.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hex.70247","type":"journal-article","created":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T10:48:59Z","timestamp":1743850139000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Influencing Factors for the Acceptability of Accessing HIV Pre\u2010exposure Prophylaxis via Community Pharmacies in Wales"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6934-2928","authenticated-orcid":false,"given":"David","family":"Gillespie","sequence":"first","affiliation":[{"name":"Centre for Trials Research, School of Medicine, College of Biomedical &amp; Life Sciences Cardiff University Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam D. N.","family":"Williams","sequence":"additional","affiliation":[{"name":"Centre for Trials Research, School of Medicine, College of Biomedical &amp; Life Sciences Cardiff University Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6877-2785","authenticated-orcid":false,"given":"Richard","family":"Ma","sequence":"additional","affiliation":[{"name":"Centre for Academic Primary Care, Bristol Medical School University of Bristol Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoe","family":"Couzens","sequence":"additional","affiliation":[{"name":"Public Health Wales NHS Trust Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerenza","family":"Hood","sequence":"additional","affiliation":[{"name":"Centre for Trials Research, School of Medicine, College of Biomedical &amp; Life Sciences Cardiff University Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dyfrig A.","family":"Hughes","sequence":"additional","affiliation":[{"name":"Centre for Health Economics and Medicines Evaluation Bangor University Bangor UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efi","family":"Mantzourani","sequence":"additional","affiliation":[{"name":"School of Pharmacy, College of Biomedical &amp; Life Sciences Cardiff University Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleanor","family":"Cochrane","sequence":"additional","affiliation":[{"name":"Health Education and Improvement Wales Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7397-4074","authenticated-orcid":false,"given":"Fiona","family":"Wood","sequence":"additional","affiliation":[{"name":"Division of Population Medicine and PRIME Centre Wales, School of Medicine, College of Biomedical &amp; Life Sciences Cardiff University Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,3]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"World Health Organization.HIV and AIDS.https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hiv-aids."},{"key":"e_1_2_11_3_1","unstructured":"UNAIDS. \u201cGlobal AIDS Strategy 2021\u20132026 End Inequalities. End AIDS \u201d2021: 16 https:\/\/www.unaids.org\/en\/Global-AIDS-Strategy-2021-2026."},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1011205"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00056-2"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(17)30089-9"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61127-7"},{"key":"e_1_2_11_8_1","unstructured":"V.Gething.Written Statement: Availability of Pre\u2010Exposure Prophylaxis (PrEP) to Prevent HIV. Welsh Government.2020 accessed May 9 2021 https:\/\/gov.wales\/written-statement-availability-pre-exposure-prophylaxis-prep-prevent-hiv."},{"key":"e_1_2_11_9_1","unstructured":"Public Health Wales.Trends in the Prevention Diagnosis and Treatment of HIV in Wales.2024 accessed January 10 2025 https:\/\/phw.nhs.wales\/publications\/publications1\/annual-hiv-report-2024\/."},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/17455057241277723"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1071\/SH22144"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-018-3379-0"},{"key":"e_1_2_11_13_1","first-page":"43","article-title":"Optimising PrEP Delivery\u2010Where and How People Want to Get PrEP. Findings From the 2020 PrEP User Survey","volume":"23","author":"Aghaizu A NLASPSJDVOGNW","year":"2022","journal-title":"HIV Medicine"},{"key":"e_1_2_11_14_1","unstructured":"Welsh Government.HIV Action Plan for Wales 2023\u20102026.2023 accessed January 10 2025 https:\/\/www.gov.wales\/sites\/default\/files\/publications\/2023-03\/hiv-action-plan-for-wales-2023-to-2026.pdf."},{"key":"e_1_2_11_15_1","unstructured":"Welsh Government.Presgripsiwn Newydd A New Prescription The Future of Community Pharmacy in Wales.2021 accessed January 10 2025 https:\/\/www.gov.wales\/sites\/default\/files\/publications\/2021-12\/a-new-prescription-the-future-of-community-pharmacy-in-wales.pdf."},{"key":"e_1_2_11_16_1","unstructured":"Welsh Government.Community Pharmacy: April 2023 to March.2024 https:\/\/www.gov.wales\/community-pharmacy-services-april-2023-march-2024-html."},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2020.07.034"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-9276-12-18"},{"key":"e_1_2_11_19_1","unstructured":"The Love Tank.Developing an HIV PrEP Need framework.2014."},{"key":"e_1_2_11_20_1","unstructured":"Fast Track Cymru accessed January 10 2025 https:\/\/fasttrack.wales\/."},{"key":"e_1_2_11_21_1","unstructured":"Terrence Higgins Trust. Terrence Higgins Trust Cymru accessed January 10 2025 https:\/\/tht.cymru\/."},{"key":"e_1_2_11_22_1","unstructured":"PrEPster accessed January 10 2025 https:\/\/prepster.info\/."},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/1049732315617444"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/2159676X.2019.1628806"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/hex.13724"},{"key":"e_1_2_11_26_1","unstructured":"UNAIDS.2024 Global AIDS Report\u2014The Urgency of Now: AIDS at a Crossroads.2024 http:\/\/www.wipo.int\/."},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2024-056308"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.26232\/full"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/1748-5908-6-42"},{"key":"e_1_2_11_30_1","unstructured":"NHS England.Pharmacy First accessed March 12 2025 https:\/\/www.england.nhs.uk\/primary-care\/pharmacy\/pharmacy-services\/pharmacy-first\/."}],"container-title":["Health Expectations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hex.70247","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T07:49:49Z","timestamp":1748072989000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hex.70247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1111\/hex.70247"],"URL":"https:\/\/doi.org\/10.1111\/hex.70247","archive":["Portico"],"relation":{},"ISSN":["1369-6513","1369-7625"],"issn-type":[{"value":"1369-6513","type":"print"},{"value":"1369-7625","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2025-01-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70247"}}