{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T03:33:24Z","timestamp":1782876804749,"version":"3.54.5"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Expectations"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study examined the content validity of EQ\u20105D for Chinese patients with DMD. Specifically, it investigated: (1) the content validity of EQ\u20105D\u20105L in adult DMD patients and (2) the content validity of EQ\u20105D\u2010Y\u20103L (Y\u20103L) in DMD patients aged 8\u201315\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>This qualitative study used semi\u2010structured interviews and conducted one\u2010on\u2010one and online, with two groups of individuals with DMD to examine the content validity of the EQ\u20105D\u20105L and Y\u20103L. All participants were recruited from a nationwide DMD patient association. The study included both adult and paediatric DMD patients. Data were analysed using a framework approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 30 interviews were completed, with 15 for adult patients and 15 for paediatric patients. Overall, EQ\u20105D\u20105L and Y\u20103L covered the most important aspects of HRQoL for DMD patients. However, many adult patients were unclear about the \u2018Mobility\u2019 item, suggesting clearer guidance on whether it refers to unaided physical mobility or mobility with assistive devices like wheelchairs. Paediatric patients felt that the three option levels were not enough to accurately describe their mobility. Both adult and paediatric patients noted that essential activities like \u2018toileting\u2019 were missing from the self\u2010care section. They also found the examples of usual activities, such as housework, to be unsuitable. Some paediatric patients disliked the examples in Y\u20103L (headaches and itchiness) and preferred having no examples at all. Regarding mental health questions, both groups struggled to connect their condition with psychological effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Both EQ\u20105D\u20105L and Y\u20103L showed acceptable content validity; however, our findings indicated the need to refine and optimise these tools to better capture critical HRQoL domains for DMD and potentially other neuromuscular diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient or Public Contribution<\/jats:title>\n                    <jats:p>The study was conducted in partnership with a DMD patient association, which played a key role in shaping the study's design and implementation. The association also contributed to reviewing the interview schedule.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hex.70431","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T16:34:11Z","timestamp":1757522051000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A Qualitative Examination of the Content Validity of the EQ\u20105D\u20105L and EQ\u20105D\u2010Y\u20103L in Adult and Paediatric Patients With Duchenne Muscular Dystrophy"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4720-5172","authenticated-orcid":false,"given":"Richard Huan","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Sciences, Faculty of Health and Social Sciences Hong Kong Polytechnic University Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Jiang","sequence":"additional","affiliation":[{"name":"Shenzhen Research Institute The Chinese University of Hong Kong Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxi","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences, Faculty of Health and Social Sciences Hong Kong Polytechnic University Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Dong","sequence":"additional","affiliation":[{"name":"JC School of Public Health and Primary Care The Chinese University of Hong Kong Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,10]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32910-1"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20586"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-018-1062-0"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2017.11.005"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-020-01511-z"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2021.03.007"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X20978390"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X211062237"},{"key":"e_1_2_12_10_1","unstructured":"National Institute for Health and Care Excellence. 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