{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:19:04Z","timestamp":1787797144378,"version":"build-2784847793"},"reference-count":79,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:00:00Z","timestamp":1787011200000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Expectations"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Despite breast cancer disproportionately affecting ethnically diverse populations, these groups remain underrepresented in UK cancer clinical trials, limiting the validity and generalisability of research findings, including treatment efficacy and safety. Around one\u2010third of the UK's ethnic minority population is Muslim, yet little is known about Muslim women's experiences of breast cancer and clinical trial participation. This study aims to explore how faith, culture and religious beliefs influence Muslim women's experiences, understanding, perceptions and participation in cancer clinical trials.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Purposive and snowball sampling were used to recruit a diverse group of Muslim women with breast cancer. Women whose first language was non\u2010English were included. Semi\u2010structured interviews were conducted either face to face, online Teams or telephone. All participants completed a demographic questionnaire. Research ambassadors, well versed in the research protocol, supported translation and participants' linguistic needs. An inductive reflexive thematic analysis (RTA) was conducted to generate codes and themes, which were then mapped onto the capability, opportunity and motivation behaviour system COM\u2010B model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fifteen Muslim women and three immediate family members were consented and interviewed. Participants were from a wide geographical area across Greater Manchester and Lancashire in the United Kingdom, representing diverse ethnicities, age and social position. Women with primary and secondary breast cancer participated; the majority were undergoing systemic anticancer therapy, and three had taken part in randomised clinical trials. RTA generated five main themes: \u2018What defines who I am,\u2019 \u2018perception of cancer,\u2019 \u2018perception and experience of clinical trials,\u2019 \u2018information &amp; education to support decision making,\u2019 and \u2018the role of the healthcare professional (HCP) in supporting trial participation.\u2019 Women's capability to participate was shaped by their knowledge of clinical trials and access to information. Opportunities were influenced by sociocultural factors, including gender roles, family expectations and HCPs' cultural competence, while motivation was shaped by women's identity, religion and trust in HCPs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study provides insight into Muslim women's health\u2010related beliefs and behaviours that influence participation in cancer clinical trials. Findings will help identify areas where action can be taken at intrapersonal, interpersonal and community level to help empower women to participate in cancer clinical trials.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient and Public Contribution<\/jats:title>\n                    <jats:p>Ethnically diverse patients and members from community grassroots organisations informed a culturally sensitive protocol. Research ambassadors contributed across the research cycle, including adapting interview materials, supporting recruitment and participation (particularly for non\u2010English speakers), and providing cultural and religious insight during analysis and interpretation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hex.70823","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T05:24:33Z","timestamp":1787117073000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Faith, Culture, and Cancer: A Qualitative Study Exploring Muslim Women's Perspectives on Clinical Trials in the United Kingdom"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2487-0540","authenticated-orcid":false,"given":"Lorraine","family":"Turner","sequence":"first","affiliation":[{"name":"Department of Research &amp; Innovation The Christie NHS Foundation Trust Manchester UK"},{"name":"Division of Nursing, Midwifery and Social Work, School of Health Sciences, Faculty of Biology, Medicine and Health The University of Manchester Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9026-1789","authenticated-orcid":false,"given":"Sally","family":"Taylor","sequence":"additional","affiliation":[{"name":"Division of Nursing, Midwifery and Social Work, School of Health Sciences, Faculty of Biology, Medicine and Health The University of Manchester Manchester UK"},{"name":"Christie Patient Centred Research The Christie NHS Foundation Trust Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5100-3000","authenticated-orcid":false,"given":"Ashleigh","family":"Ward","sequence":"additional","affiliation":[{"name":"Christie Patient Centred Research The Christie NHS Foundation Trust Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nighat","family":"Ahmed","sequence":"additional","affiliation":[{"name":"PPI Independent Contributor Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1344-5944","authenticated-orcid":false,"given":"Janelle","family":"Yorke","sequence":"additional","affiliation":[{"name":"Christie Patient Centred Research The Christie NHS Foundation Trust Manchester UK"},{"name":"School of Nursing The Hong Kong Polytechnic University Hong Kong, SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,18]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/13557858.2016.1182126"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-021-01240-x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.56726\/IRJMETS48449"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-020-01045-4"},{"key":"e_1_2_11_6_1","volume-title":"Breast Cancer [Internet]","author":"World Health Organization","year":"2025"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-022-02260-0"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/07399332.2013.857323"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16091726"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.22.00754"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.35.15_suppl.2533"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conctc.2020.100532"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.32755"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djaa155"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/NCC.0000000000001399"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-021-01489-2"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-016-0319-1"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12939-025-02431-4"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-021-05849-7"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djy221"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2018.36.6_suppl.73"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-20-3852"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp2107331"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.52.3.134"},{"key":"e_1_2_11_26_1","first-page":"3061","article-title":"Health Literacy, Social Determinants of Health, and Disease Prevention and Control","volume":"6","author":"Coughlin S. 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