{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T18:39:10Z","timestamp":1792435150901,"version":"4.5.0"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Expectations"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The James Lind Alliance Children's Cancer Priority Setting Partnership identified 23 key research topics, as defined by children, survivors, families, carers, and professionals. Funders have expressed commitment to ensuring all priorities are addressed. The aim of our current project was to map UK\u2010funded childhood cancer research against the 23 priorities to highlight gaps and inform future funding, policy and research directions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective grant mapping study. Potential UK funders of childhood cancer research were contacted for details of projects funded January 2020\u2013July 2025. Project abstracts were reviewed to map study aims to one or more of the 23 priorities. Total funding, co\u2010funders, type of cancer and study design were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 63 funders contacted, nine declined to participate, eight gave no response and 19 were ineligible as they had not funded relevant work in the study timeframe. Twenty\u2010seven funders provided data and three had online searchable databases, allowing direct data extraction: 452 studies were mapped. Studies covered all major childhood cancers; 75% were pre\u2010clinical in design. Total funding awarded was nearly \u00a3113 million with 39 co\u2010funded studies. Priority 1:\n                      <jats:italic>Developing effective and kinder treatments<\/jats:italic>\n                      received most research focus: with 365 studies and \u00a394.2 million funding. Other well\u2010addressed priorities were Priority 2:\n                      <jats:italic>Why children develop cancer and can it be prevented<\/jats:italic>\n                      : with 73 studies and \u00a316.6 million funding; and Priority 5:\n                      <jats:italic>Reasons for relapse<\/jats:italic>\n                      \u2212 44 studies and \u00a39.6 million. Five priorities received no funding, including Priority 6:\n                      <jats:italic>Improving hospital experience<\/jats:italic>\n                      , which was the top priority identified by children.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>While treatment research is well supported, some areas that matter to children, survivors, families and health professionals are overlooked. Funders and researchers should target underrepresented priorities. Policy makers can use findings to inform delivery of the National Cancer Plan. Patients and families can raise awareness of underfunded areas and influence funding decisions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient or Public Contribution<\/jats:title>\n                    <jats:p>This mapping project stemmed from a James Lind Alliance Priority Setting Partnership that had at its core an emphasis on patient participation. Our project team included a survivor of childhood cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hex.70845","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:43:36Z","timestamp":1787798616000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Does Current United Kingdom Childhood Cancer Research Address the James Lind Alliance Children's Cancer Priority Setting Partnership Priorities? A Grant Mapping Study"],"prefix":"10.1111","volume":"29","author":[{"given":"Alison","family":"Bish","sequence":"first","affiliation":[{"name":"School of Health Sciences University of Surrey Guildford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8125-4584","authenticated-orcid":false,"given":"Faith","family":"Gibson","sequence":"additional","affiliation":[{"name":"School of Health Sciences University of Surrey Guildford UK"},{"name":"Centre for Outcomes and Experience Research in Children's Health, Illness and Disability (ORCHID) Great Ormond Street Hospital for Children NHS Foundation Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Brownsdon","sequence":"additional","affiliation":[{"name":"Patient representative Exeter Devon UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3479-7997","authenticated-orcid":false,"given":"Julia","family":"Chisholm","sequence":"additional","affiliation":[{"name":"The Royal Marsden NHS Foundation Trust Sutton UK"},{"name":"Institute of Cancer Research Sutton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8933-117X","authenticated-orcid":false,"given":"Jenny","family":"Harris","sequence":"additional","affiliation":[{"name":"School of Health Sciences University of Surrey Guildford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Hollis","sequence":"additional","affiliation":[{"name":"Rachel Hollis Leeds Children's Hospital Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4938-9673","authenticated-orcid":false,"given":"Bob","family":"Phillips","sequence":"additional","affiliation":[{"name":"Rachel Hollis Leeds Children's Hospital Leeds UK"},{"name":"University of York York UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6015-6993","authenticated-orcid":false,"given":"Susie","family":"Aldiss","sequence":"additional","affiliation":[{"name":"School of Health Sciences University of Surrey Guildford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Public Health England. (2021).Children Teenagers and Young Adults UK Cancer Statistics Report 2021. Retrieved 9 April fromhttps:\/\/digital.nhs.uk\/ndrs\/data\/data-outputs\/cancer-publications-and-tools\/ctya-uk-cancer-statistics-report-2021."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1188\/18.Onf.527-544"},{"key":"e_1_2_10_4_1","unstructured":"Cancer Research UK. (2016).Children's Cancers Survival Statistics. Retrieved 9th April fromhttps:\/\/www.cancerresearchuk.org\/health-professional\/cancer-statistics\/statistics-by-cancer-type\/childrens-cancers."},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2023-077387"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40900-023-00518-2"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40900-020-00210-9"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/ncc.0000000000000702"},{"key":"e_1_2_10_9_1","doi-asserted-by":"crossref","unstructured":"J.Crooks E.Carduff B.Hudson et al. (2023).Addressing the Palliative and End of Life Care Research Priorities An Updated Grant Mapping Analysis.https:\/\/healthopenresearch.org\/documents\/5-32.","DOI":"10.21955\/healthopenres.1115005.1"},{"key":"e_1_2_10_10_1","unstructured":"F. ToddFordham B.Candy S.McMillan et al. \u201cDoes Current Palliative and End of Life Care Research Match the Priorities of Patients Carers and Clinicians? \u201d A Grant Mapping Analysis of the UK Clinical Research Collaboration's Health Research Classification System dataset 2014. (2017) https:\/\/www.mariecurie.org.uk\/globalassets\/media\/documents\/research\/publications\/grant-mapping-report.pdf."},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3310\/btbd8846"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/hex.14096"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-016540"},{"key":"e_1_2_10_14_1","unstructured":"Department of Health and Social Care and NHS England. (2026).National Cancer Plan for England.https:\/\/www.gov.uk\/government\/publications\/national-cancer-plan-for-england."},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/cnr2.1835"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/cnr2.2071"}],"container-title":["Health Expectations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hex.70845","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/hex.70845","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hex.70845","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T17:41:25Z","timestamp":1792431685000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hex.70845"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,26]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/hex.70845"],"URL":"https:\/\/doi.org\/10.1111\/hex.70845","archive":["Portico"],"relation":{},"ISSN":["1369-6513","1369-7625"],"issn-type":[{"value":"1369-6513","type":"print"},{"value":"1369-7625","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,26]]},"assertion":[{"value":"2026-05-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70845"}}