{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T15:12:24Z","timestamp":1785683544803,"version":"3.56.0"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,4,18]],"date-time":"2013-04-18T00:00:00Z","timestamp":1366243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      Both lupus panniculitis (\n                      <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>\n                      ) and subcutaneous panniculitis\u2010like T\u2010cell lymphoma (\n                      <jats:styled-content style=\"fixed-case\">SPTCL<\/jats:styled-content>\n                      ) are characterized by subcutaneous lobular lymphocytic infiltrates, and they are sometimes difficult to differentiate. Recently, plasmacytoid dendritic cells (\n                      <jats:styled-content style=\"fixed-case\">PDC<\/jats:styled-content>\n                      s) were found to be present in various types of cutaneous lupus erythematosus lesions, including\n                      <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>\n                      , and are supposed to play important pathogenetic roles. The aim of this study was to investigate whether\n                      <jats:styled-content style=\"fixed-case\">PDC<\/jats:styled-content>\n                      s are differentially present in these two diseases and can be utilized to differentiate them. Conventional histopathological features were also compared.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>\n                      Initial biopsies from 21\n                      <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>\n                      and 11\n                      <jats:styled-content style=\"fixed-case\">SPTCL<\/jats:styled-content>\n                      patients were analysed. Our results showed that the presence of lymphoid follicles, dermal mucin deposition and lack of moderate to marked nuclear atypia or adipocyte rimming were more suggestive of\n                      <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>\n                      . Several distinct patterns of fat necrosis, i.e. hyaline\/lipomembranous and fibrinoid\/coagulative in\n                      <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">SPTCL<\/jats:styled-content>\n                      , respectively, were also diagnostically useful. Also, clusters of\n                      <jats:styled-content style=\"fixed-case\">PDC<\/jats:styled-content>\n                      s were characteristically seen in\n                      <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>\n                      lesions (17\/21, 81%) but not in\n                      <jats:styled-content style=\"fixed-case\">SPTCL<\/jats:styled-content>\n                      lesions (2\/11, 18.2%). In\n                      <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>\n                      lesions, but not in\n                      <jats:styled-content style=\"fixed-case\">SPTCL<\/jats:styled-content>\n                      lesions, the presence of epidermal interface change correlated perfectly with the presence of\n                      <jats:styled-content style=\"fixed-case\">PDC<\/jats:styled-content>\n                      s in the papillary dermis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      We conclude that the presence of clusters of\n                      <jats:styled-content style=\"fixed-case\">PDC<\/jats:styled-content>\n                      s and certain histological features are helpful for the differential diagnosis.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/his.12105","type":"journal-article","created":{"date-parts":[[2013,1,30]],"date-time":"2013-01-30T21:34:46Z","timestamp":1359581686000},"page":"1057-1066","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["The presence of clusters of plasmacytoid dendritic cells is a helpful feature for differentiating lupus panniculitis from subcutaneous panniculitis\u2010like\n                    <scp>T<\/scp>\n                    \u2010cell lymphoma"],"prefix":"10.1111","volume":"62","author":[{"given":"Jau\u2010Yu","family":"Liau","sequence":"first","affiliation":[{"name":"Department of Pathology College of Medicine National Taiwan University Hospital National Taiwan University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih\u2010Sung","family":"Chuang","sequence":"additional","affiliation":[{"name":"Department of Pathology Chi\u2010Mei Medical Centre Tainan and Taipei Medical University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia\u2010Yu","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Dermatology College of Medicine National Taiwan University Hospital National Taiwan University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Hui","family":"Ku","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Koo Foundation Sun Yat\u2010Sen Cancer Centre Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia\u2010Huei","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Pathology College of Medicine National Taiwan University Hospital National Taiwan University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teng\u2010Fu","family":"Shih","sequence":"additional","affiliation":[{"name":"Department of Pathology Yuan's General Hospital Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,4,18]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"68","article-title":"Lupus panniculitis: clinical perspectives from a case series","volume":"26","author":"Martens PB","year":"1999","journal-title":"J. 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