{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T13:47:56Z","timestamp":1785678476529,"version":"3.56.0"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,7,3]],"date-time":"2013-07-03T00:00:00Z","timestamp":1372809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">SALL<\/jats:styled-content>4 is a marker of germ cell tumours. The aim of this study was to investigate <jats:styled-content style=\"fixed-case\">SALL<\/jats:styled-content>4 expression in blastemal tumours, particularly in hepatoblastoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>The study included 12 hepatoblastomas. Eight hepatoblastomas were pure epithelial tumours, and four were mixed epithelial and mesenchymal tumours. The patients were nine males and three females with a mean age of 14.6\u00a0months. Immunohistochemistry was performed with an antibody against <jats:styled-content style=\"fixed-case\">SALL<\/jats:styled-content>4, using an automated immunostainer. Seven of 12 hepatoblastomas showed nuclear staining only in the embryonal component. Fetal and mesenchymal components were negative.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">SALL<\/jats:styled-content>4 is expressed in blastemal tumours, particularly in the embryonal subtype of hepatoblastoma. Pathologists need to be aware of such expression so that misdiagnosis can be avoided.<\/jats:p><\/jats:sec>","DOI":"10.1111\/his.12187","type":"journal-article","created":{"date-parts":[[2013,5,15]],"date-time":"2013-05-15T04:33:38Z","timestamp":1368592418000},"page":"425-428","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["<scp>SALL<\/scp>4 is a marker of the embryonal subtype of hepatoblastoma"],"prefix":"10.1111","volume":"63","author":[{"given":"Viviane","family":"Gnemmi","sequence":"first","affiliation":[{"name":"Department of Pathology University Hospital CHRU Lille France"},{"name":"University Lille Nord de France Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Leteurtre","sequence":"additional","affiliation":[{"name":"Department of Pathology University Hospital CHRU Lille France"},{"name":"University Lille Nord de France Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Sudour\u2010Bonnange","sequence":"additional","affiliation":[{"name":"Department of Paediatric Oncology Anticancer Center Oscar Lambret Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Devisme","sequence":"additional","affiliation":[{"name":"Department of Pathology University Hospital CHRU Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Guettier","sequence":"additional","affiliation":[{"name":"Department of Pathology CHU Bicetre, Le Kremlin Bicetre Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Buob","sequence":"additional","affiliation":[{"name":"Department of Pathology University Hospital CHRU Lille France"},{"name":"University Lille Nord de France Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Leroy","sequence":"additional","affiliation":[{"name":"Department of Pathology University Hospital CHRU Lille France"},{"name":"University Lille Nord de France Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2011.10.011"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24215"},{"key":"e_1_2_5_4_1","first-page":"228","volume-title":"World Health Organization classification of tumours of the digestive system","author":"Zimmermann A","year":"2000"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24214"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2008.07.022"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24308"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0010766"},{"key":"e_1_2_5_9_1","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1097\/PAS.0b013e3181db84aa","article-title":"Diagnostic utility of novel stem cell markers SALL4, OCT4, NANOG, SOX2, UTF1 and TCL1 in primary mediastinal germ cell tumors","volume":"34","author":"Liu A","year":"2010","journal-title":"Am. 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