{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:41:26Z","timestamp":1791823286587,"version":"4.3.4"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,11,28]],"date-time":"2014-11-28T00:00:00Z","timestamp":1417132800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>To report a series of 10 cervical adenomyomas of endocervical type and the first case of a mesonephric adenomyoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>The patients\u2019 ages ranged from 30 to 55\u00a0years. Most lesions were grossly polypoid; a minority were intramural or exophytic. In six of seven endocervical adenomyomas received in consultation, adenoma malignum was considered. A variety of benign lesions, including lobular endocervical glandular hyperplasia (<jats:styled-content style=\"fixed-case\">LEGH<\/jats:styled-content>), adenofibroma, endocervicosis and tunnel clusters, were also considered. The endocervical adenomyomas consisted of bland mucinous glands, sometimes with focal epithelial metaplasia, within a prominent smooth muscle stroma. There was usually a focal lobular architecture and sometimes papillary infoldings. A characteristic feature was a rim of stroma surrounding glands, surrounded in turn by smooth muscle. Previously undescribed features were \u2018symplastic\u2010like\u2019 smooth muscle, stromal adipose tissue, gland rupture with mucin extravasation, prominent adenofibroma\u2010like areas and surface cervical intraepithelial neoplasia (<jats:styled-content style=\"fixed-case\">CIN<\/jats:styled-content>). Diffuse oestrogen receptor (<jats:styled-content style=\"fixed-case\">ER<\/jats:styled-content>) immunoreactivity was useful in excluding adenoma malignum and <jats:styled-content style=\"fixed-case\">LEGH<\/jats:styled-content>, which are hormone receptor\u2010negative. The mesonephric adenomyoma consisted of a lobular arrangement of mesonephric glands [<jats:styled-content style=\"fixed-case\">ER<\/jats:styled-content>\/progesterone receptor (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>)\u2010negative; vimentin and luminal <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>10 immunoreactivity] within a smooth muscle stroma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Endocervical and mesonephric adenomyomas are rare lesions which are often misdiagnosed, possibly because of lack of familiarity among pathologists.<\/jats:p><\/jats:sec>","DOI":"10.1111\/his.12546","type":"journal-article","created":{"date-parts":[[2014,9,15]],"date-time":"2014-09-15T07:11:44Z","timestamp":1410765104000},"page":"420-429","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Adenomyomas of the uterine cervix: report of a cohort including endocervical and novel variants"],"prefix":"10.1111","volume":"66","author":[{"given":"Shauna","family":"Casey","sequence":"first","affiliation":[{"name":"Department of Pathology Belfast Health and Social Care Trust Belfast UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W Glenn","family":"McCluggage","sequence":"additional","affiliation":[{"name":"Department of Pathology Belfast Health and Social Care Trust Belfast UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,28]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"220","article-title":"Adenomyomas of the uterine cervix of of endocervical type: a report of ten cases of a benign cervical tumor that may be confused with adenoma malignum","volume":"9","author":"Gilks CB","year":"1996","journal-title":"Mod. 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