{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T21:22:22Z","timestamp":1778534542836,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,7,28]],"date-time":"2015-07-28T00:00:00Z","timestamp":1438041600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Capital Health Development Special Research Foundation","award":["2014-2-2013"],"award-info":[{"award-number":["2014-2-2013"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>To study three atypical glioneuronal tumours (<jats:styled-content style=\"fixed-case\">GNT<\/jats:styled-content>s), in order to shed light on the clinical and pathological features of this diverse tumour group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Clinical and neuropathological data for each case were retrospectively reviewed. Case 1 involved a 17\u2010year\u2010old boy with left leg movement difficulty. A mass lesion in the basal ganglia was detected radiologically; histopathological features included neurocytic\/perivascular rosettes and a pilocytic astrocytoma component. Case 2 involved a 33\u2010year\u2010old man with intractable epilepsy. His left parietal lobe contained a cyst\u2010like mass, resembling dysembryoplastic neuroepithelial tumour and rosette\u2010forming glioneuronal tumour of the fourth ventricle microscopically. Case 3 involved a 21\u2010year\u2010old woman with a mass lesion in the mesencephalic tegmentum extending to the third and fourth ventricles and the suprasellar region. The lesion contained perivascular\/neurocytic rosettes and an oligodendroglioma\u2010like component. None of the tumours expressed an isocitrate dehydrogenase I mutation of the R132H type or contained a 1p\/19q deletion, a <jats:italic>BRAF<\/jats:italic><jats:sup>V600E<\/jats:sup> mutation, or <jats:italic>KIAA1549\u2013BRAF<\/jats:italic> fusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We describe three <jats:styled-content style=\"fixed-case\">GNT<\/jats:styled-content>s with atypical histopathology and locations. Additional cases and molecular studies are needed to better understand the biological nature of <jats:styled-content style=\"fixed-case\">GNT<\/jats:styled-content>s and to refine their classification system.<\/jats:p><\/jats:sec>","DOI":"10.1111\/his.12750","type":"journal-article","created":{"date-parts":[[2015,6,3]],"date-time":"2015-06-03T16:35:55Z","timestamp":1433349355000},"page":"378-387","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Glioneuronal tumours with features of rosette\u2010forming glioneuronal tumours of the fourth ventricle and dysembryoplastic neuroepithelial tumours: a report of three cases"],"prefix":"10.1111","volume":"68","author":[{"given":"Shi\u2010Yun","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Neuropathology Xuanwu Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neuropathology Xuanwu Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei\u2010Ming","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neuropathology Xuanwu Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing\u2010Tang","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Xuanwu Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo\u2010Guang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Xuanwu Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geng","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Xuanwu Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"De\u2010Hong","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Neuropathology Xuanwu Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue\u2010Shan","family":"Piao","sequence":"additional","affiliation":[{"name":"Department of Neuropathology Xuanwu Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,7,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-2097"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2013.02.013"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-007-0243-4"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3639.2012.00582.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200205000-00004"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12457"},{"key":"e_1_2_8_8_1","first-page":"175","article-title":"Dysembryoplastic neuroepithelial micro\u2010tumor in a 75\u2010year\u2010old patient with long\u2010standing epilepsy","volume":"12","author":"Gottschalk J","year":"1993","journal-title":"Clin. Neuropathol."},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198811000-00002"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006193018140"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/neup.12026"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/neup.12124"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/neup.12000"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000345640.40566.48"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2006.104.1.62"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004010050852"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.440150304"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/303390a0"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(91)90381-9"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-010-0695-9"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/61.11.947"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-006-0153-x"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-012-0940-2"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-009-0569-1"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-009-0561-9"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-004-2748-1"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/NEN.0b013e3182302475"}],"container-title":["Histopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhis.12750","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/his.12750","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T02:56:33Z","timestamp":1696301793000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/his.12750"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,28]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1111\/his.12750"],"URL":"https:\/\/doi.org\/10.1111\/his.12750","archive":["Portico"],"relation":{},"ISSN":["0309-0167","1365-2559"],"issn-type":[{"value":"0309-0167","type":"print"},{"value":"1365-2559","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,28]]},"assertion":[{"value":"2015-03-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-05-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-07-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}