{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T07:43:59Z","timestamp":1770882239972,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,10,28]],"date-time":"2015-10-28T00:00:00Z","timestamp":1445990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>Inflammatory pseudotumour\u2010like follicular dendritic cell (<jats:styled-content style=\"fixed-case\">FDC<\/jats:styled-content>) tumour is an extremely rare neoplasm. Herein, we report 10 cases of inflammatory pseudotumour\u2010like <jats:styled-content style=\"fixed-case\">FDC<\/jats:styled-content> tumours in the abdomen and analyse their clinicopathological features.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Seven patients were male, and three patients were female. The patients' age ranged from 28 years to 68 years (mean age, 52.9 years; median age, 51.5 years). Grossly, the tumour was usually solitary, well circumscribed, and solid, ranging from 23 mm to 233 mm in greatest diameter. Microscopically, the tumour was composed of variable amounts of spindle tumour cells with intense lymphoplasmacytic infiltrate. Unusual morphological findings, including eosinophils focally aggregated in one tumour admixed with multinucleated histiocytes in small clusters, fibrinoid deposits in the walls of ectatic blood vessel with occasional perivascular cuffs of lymphocytes, hyalinized fibrosis, and epithelioid granuloma, were identified. The tumour cells were immunoreactive for <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>21, <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>23, <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>35, smooth muscle actin, and Epstein\u2013Barr virus (<jats:styled-content style=\"fixed-case\">EBV<\/jats:styled-content>)\u2010encoded latent membrane protein 1 (7\/10, 70%). <jats:styled-content style=\"fixed-case\">EBV<\/jats:styled-content>\u2010encoded small <jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content> was positive in all cases by <jats:italic>in situ<\/jats:italic> hybridization. The recurrence rate was 10% with a median follow\u2010up of 19 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Inflammatory pseudotumour\u2010like <jats:styled-content style=\"fixed-case\">FDC<\/jats:styled-content> tumour should be differentiated from inflammatory myofibroblastic tumour, Hodgkin lymphoma, interdigitating dendritic cell sarcoma, and gastrointestinal stromal tumour.<\/jats:p><\/jats:sec>","DOI":"10.1111\/his.12851","type":"journal-article","created":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T20:04:37Z","timestamp":1441224277000},"page":"858-865","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Clinicopathological features of inflammatory pseudotumour\u2010like follicular dendritic cell tumour of the abdomen"],"prefix":"10.1111","volume":"68","author":[{"given":"Yanyang","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Pathology The First Affiliated Hospital Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huijuan","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Pathology The First Affiliated Hospital Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pathology The First Affiliated Hospital Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiantian","family":"Zhen","sequence":"additional","affiliation":[{"name":"Department of Pathology The First Affiliated Hospital Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anjia","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pathology The First Affiliated Hospital Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,10,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199603000-00008"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200106000-00003"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2463\/mrms.2014-0052"},{"key":"e_1_2_7_5_1","first-page":"489","article-title":"Epstein\u2010Barr virus positive inflammatory pseudotumor of the liver: report of a challenging case and review of the literature","volume":"44","author":"You Y","year":"2014","journal-title":"Ann. 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