{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T09:20:28Z","timestamp":1792315228118,"version":"4.4.0"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,10,17]],"date-time":"2017-10-17T00:00:00Z","timestamp":1508198400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001171","name":"Cancer Institute NSW","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>Early recognition and accurate diagnosis underpins melanoma survival. Identifying early melanomas arising in association with pre\u2010existing lesions is often challenging. Clinically suspicious foci, however small, must be identified and examined histologically. This study assessed the accuracy of punch biopsy \u2018scoring\u2019 of suspicious foci in excised atypical pigmented skin lesions to identify early melanomas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Forty\u2010one excised pigmented skin lesions with a clinically\/dermoscopically focal area of concern for melanoma, with the suspicious focus marked prior to excision with a punch biopsy \u2018score\u2019 (a partial incision into the skin surface), were analysed. Melanoma was diagnosed in nine of 41 cases (22%). In eight of nine cases (89%) the melanoma was associated with a naevus, and in seven of nine (88%) cases the melanoma was identified preferentially by the scored focus. In six of nine cases (67%), the melanoma was entirely encompassed by the scored focus. In one case of melanoma<jats:italic>in situ<\/jats:italic>, the diagnostic material was identified only on further levelling through the scored focus. In 28 of 32 of non\u2010melanoma cases (88%), the scored focus identified either diagnostic features of a particular lesion or pathological features that correlated with the clinical impression of change\/atypia including altered architecture or distribution of pigmentation, features of irritation or regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The \u2018punch scoring technique\u2019 allows direct clinicopathological correlation and facilitates early melanoma diagnosis by focusing attention on clinically suspicious areas. Furthermore, it does not require special expertise in<jats:italic>ex\u2010vivo<\/jats:italic>clinical techniques for implementation. Nevertheless, in some cases examination of the lesion beyond the scored focus is also necessary to make a diagnosis of melanoma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/his.13342","type":"journal-article","created":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T17:52:40Z","timestamp":1502387560000},"page":"294-304","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Punch \u2018scoring\u2019: a technique that facilitates melanoma diagnosis of clinically suspicious pigmented lesions"],"prefix":"10.1111","volume":"72","author":[{"given":"Judith","family":"Grogan","sequence":"first","affiliation":[{"name":"Department of Tissue Pathology and Diagnostic Oncology Royal Prince Alfred Hospital Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline L","family":"Cooper","sequence":"additional","affiliation":[{"name":"Department of Tissue Pathology and Diagnostic Oncology Royal Prince Alfred Hospital Sydney NSW Australia"},{"name":"Sydney Medical School The University of Sydney Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristan J","family":"Dodds","sequence":"additional","affiliation":[{"name":"Department of Tissue Pathology and Diagnostic Oncology Royal Prince Alfred Hospital Sydney NSW Australia"},{"name":"Sydney Medical School The University of Sydney Sydney NSW Australia"},{"name":"Melanoma Institute Australia The University of Sydney Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Guitera","sequence":"additional","affiliation":[{"name":"Sydney Medical School The University of Sydney Sydney NSW Australia"},{"name":"Melanoma Institute Australia The University of Sydney Sydney NSW Australia"},{"name":"Sydney Melanoma Diagnostic Centre Royal Prince Alfred Hospital Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6430-6429","authenticated-orcid":false,"given":"Scott W","family":"Menzies","sequence":"additional","affiliation":[{"name":"Sydney Medical School The University of Sydney Sydney NSW Australia"},{"name":"Sydney Melanoma Diagnostic Centre Royal Prince Alfred Hospital Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard A","family":"Scolyer","sequence":"additional","affiliation":[{"name":"Department of Tissue Pathology and Diagnostic Oncology Royal Prince Alfred Hospital Sydney NSW Australia"},{"name":"Sydney Medical School The University of Sydney Sydney NSW Australia"},{"name":"Melanoma Institute Australia The University of Sydney Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,10,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.20083"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/00313020412331283897"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14749"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12839"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1038\/jid.2010.84","article-title":"The impact of in vivo reflectance confocal microscopy on the diagnostic accuracy of lentigo maligna and equivocal pigmented and nonpigmented macules of the face","volume":"130","author":"Guitera P","year":"2010","journal-title":"J. Clin. Invest. Dermatol."},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.08.022"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.3.349"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1993.tb00228.x"},{"issue":"4","key":"e_1_2_7_10_1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.47102\/annals-acadmedsg.V33N4p3S","article-title":"Melanocytic lesions of the face: diagnostic pitfalls","volume":"33","author":"McCarthy SW","year":"2004","journal-title":"Ann. Acad. Med. Singapore"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathol.2015.12.009"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2009.06.003"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2009.06.004"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2009.07.001"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08713.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.328"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.10194.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2008.193"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0846.2009.00402.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.2.155"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soc.2010.09.006"},{"key":"e_1_2_7_22_1","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.5858\/2009-0612-RAR.1","article-title":"Histologically ambiguous (\u2018borderline\u2019) primary cutaneous melanocytic tumors: approaches to patient management, including the roles of molecular testing and sentinel lymph node biopsy","volume":"134","author":"Scolyer RA","year":"2010","journal-title":"Arch. Pathol. Lab. Med."},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2006.00230.x"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.14"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)70937-5"},{"key":"e_1_2_7_26_1","first-page":"487","article-title":"Melanoma management in 2007","volume":"36","author":"Thompson JF","year":"2007","journal-title":"Aust. Fam. Physician"},{"key":"e_1_2_7_27_1","first-page":"22","article-title":"Clinicopathologic correlation of pigmented skin lesions using dermoscopy","volume":"10","author":"Soyer HP","year":"2000","journal-title":"Eur. J. Dermatol."},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1258\/135763304322764176"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31829d7f35"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1996.tb01295.x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.137.10.1338"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.6.734"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005375"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.6.723"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200309000-00012"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.10.035"},{"key":"e_1_2_7_37_1","first-page":"168","article-title":"Limitations of histopathologic analysis in the recognition of melanoma: a plea for a combined diagnostic approach of histopathologic and dermoscopic evaluation","volume":"52","author":"Soyer HP","year":"2005","journal-title":"Arch. Dermatol."},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962009000500021"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199308000-00001"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.12.1548"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.144.12.1597"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07342.x"}],"container-title":["Histopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhis.13342","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/his.13342","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T04:29:19Z","timestamp":1719376159000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/his.13342"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,17]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1111\/his.13342"],"URL":"https:\/\/doi.org\/10.1111\/his.13342","archive":["Portico"],"relation":{},"ISSN":["0309-0167","1365-2559"],"issn-type":[{"value":"0309-0167","type":"print"},{"value":"1365-2559","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,17]]},"assertion":[{"value":"2017-05-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-08-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-10-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}