{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T23:23:54Z","timestamp":1792106634598,"version":"4.4.0"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,8,19]],"date-time":"2018-08-19T00:00:00Z","timestamp":1534636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"La Fondation du souffle"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      Non\u2010infectious pulmonary complications (\n                      <jats:styled-content style=\"fixed-case\">NIPC<\/jats:styled-content>\n                      s) occur frequently following allogeneic haematopoietic stem cell transplantation (\n                      <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content>\n                      ). As there is no consensus on the description of the related pulmonary pathological lesions, pathologist reports and clinical conclusions are largely inconsistent in routine practice. The aim of our study was to provide an accurate overview of post\u2010allogeneic\n                      <jats:styled-content style=\"fixed-case\">HSCT NIPC<\/jats:styled-content>\n                      s from a large number of lung biopsies.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>\n                      We reviewed 61 lung biopsies in patients with an\n                      <jats:styled-content style=\"fixed-case\">NIPC<\/jats:styled-content>\n                      , including 51 surgical lung biopsies, four post\u2010mortem biopsies and six lung explants. We found both bronchiolar (\n                      <jats:italic>n<\/jats:italic>\n                      = 59) and alveolar\/interstitial pathologies (\n                      <jats:italic>n<\/jats:italic>\n                      = 27). We describe two types of bronchiolar lesions: bronchiolectasies (\n                      <jats:italic>n<\/jats:italic>\n                      = 37) and fibrous and cellular lesions with luminal narrowing (\n                      <jats:italic>n<\/jats:italic>\n                      = 43). We found a wide spectrum of airway\/interstitial pathologies that were labelled using the terminology of the 2013 American Thoracic Society and European Respiratory Society (\n                      <jats:styled-content style=\"fixed-case\">ATS<\/jats:styled-content>\n                      \/\n                      <jats:styled-content style=\"fixed-case\">ERS<\/jats:styled-content>\n                      ) classification of idiopathic interstitial pneumonias (\n                      <jats:styled-content style=\"fixed-case\">IIP<\/jats:styled-content>\n                      s), including the following: organising pneumonia (\n                      <jats:styled-content style=\"fixed-case\">OP<\/jats:styled-content>\n                      ,\n                      <jats:italic>n<\/jats:italic>\n                      = 8), non\u2010specific interstitial pneumonia (\n                      <jats:styled-content style=\"fixed-case\">NSIP<\/jats:styled-content>\n                      ,\n                      <jats:italic>n<\/jats:italic>\n                      = 9), diffuse alveolar damage (\n                      <jats:styled-content style=\"fixed-case\">DAD<\/jats:styled-content>\n                      ,\n                      <jats:italic>n<\/jats:italic>\n                      = 6), lymphoid interstitial pneumonia (\n                      <jats:styled-content style=\"fixed-case\">LIP<\/jats:styled-content>\n                      ,\n                      <jats:italic>n<\/jats:italic>\n                      = 1) and pleuroparenchymal fibroelastosis (\n                      <jats:styled-content style=\"fixed-case\">PPFE<\/jats:styled-content>\n                      ,\n                      <jats:italic>n<\/jats:italic>\n                      = 2), as well as one instance of associated\n                      <jats:styled-content style=\"fixed-case\">PPFE<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">NSIP<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Interstitial pathology was associated with bronchiolar lesions in 41% of the cases reviewed (\n                      <jats:italic>n<\/jats:italic>\n                      = 25). Lung airway and interstitial inflammation was still present in lung explants from patients who underwent lung transplantation for post\u2010allogeneic\n                      <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content>\n                      end\u2010stage respiratory insufficiency. Herein, we describe a wide spectrum of pathological lung lesions encountered in post\u2010allogeneic\n                      <jats:styled-content style=\"fixed-case\">HSCT NIPC<\/jats:styled-content>\n                      s.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/his.13697","type":"journal-article","created":{"date-parts":[[2018,6,28]],"date-time":"2018-06-28T16:10:14Z","timestamp":1530202214000},"page":"832-842","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Lung histopathology of non\u2010infectious pulmonary complications after allogeneic haematopoietic stem cell transplantation"],"prefix":"10.1111","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0502-9489","authenticated-orcid":false,"given":"Veronique","family":"Meignin","sequence":"first","affiliation":[{"name":"Service de Pathologie H\u00f4pital Saint\u2010Louis Assistance Publique\u2010H\u00f4pitaux de Paris Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francoise","family":"Thivolet\u2010Bejui","sequence":"additional","affiliation":[{"name":"Service de Pathologie Groupement hospitalier est, Hospices de Lyon Universit\u00e9 Claude Bernard Lyon Est Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Kambouchner","sequence":"additional","affiliation":[{"name":"Service de Pathologie H\u00f4pital Avicenne Assistance Publique\u2010H\u00f4pitaux de Paris Bobigny France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Hussenet","sequence":"additional","affiliation":[{"name":"Service de Pneumologie Assistance Publique\u2010H\u00f4pitaux de Paris H\u00f4pital Saint\u2010Louis Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Bondeelle","sequence":"additional","affiliation":[{"name":"Service de Pneumologie Assistance Publique\u2010H\u00f4pitaux de Paris H\u00f4pital Saint\u2010Louis Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Service de Pathologie Universit\u00e9 de Montr\u00e9al H\u00f4pital Maisonneuve\u2010Rosemont Montr\u00e9al Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karine","family":"Chagnon","sequence":"additional","affiliation":[{"name":"Service de Pneumologie Universit\u00e9 de Montr\u00e9al H\u00f4pital Maisonneuve\u2010Rosemont Montr\u00e9al Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugues","family":"Begueret","sequence":"additional","affiliation":[{"name":"Service de Pathologie H\u00f4pital Haut L\u00e9v\u00eaque Groupe hospitalier sud, CHU de Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie","family":"Segers","sequence":"additional","affiliation":[{"name":"Service de Pathologie CHU Brugmann Bruxelles Belgique"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Cottin","sequence":"additional","affiliation":[{"name":"Service de pneumologie Hospices Civils de Lyon Lyon France"},{"name":"H\u00f4pital Louis Pradel Centre de r\u00e9f\u00e9rence national des maladies pulmonaires rares et Centre de comp\u00e9tences de l'hypertension art\u00e9rielle pulmonaire Universit\u00e9 de Lyon Universit\u00e9 Claude Bernard Lyon Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdellatif","family":"Tazi","sequence":"additional","affiliation":[{"name":"Service de Pneumologie Assistance Publique\u2010H\u00f4pitaux de Paris H\u00f4pital Saint\u2010Louis Paris 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Paris France"},{"name":"Biostatistics and Clinical Epidemiology Research Team Universit\u00e9 Paris Diderot Sorbonne Paris Cit\u00e9 Paris 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