{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:28:16Z","timestamp":1792798096256,"version":"4.5.0"},"reference-count":126,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T00:00:00Z","timestamp":1545091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Charles University Research Fund","award":["00669806"],"award-info":[{"award-number":["00669806"]}],"id":[{"id":"https:\/\/ror.org\/024d6js02","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>\n                    Renal tumours include a heterogeneous and diverse spectrum of neoplasms. Recent advances in this field have significantly improved our understanding of the morphological, immunohistochemical, molecular, epidemiological and clinical characteristics of renal tumours, which led to the new Vancouver classification of renal neoplasia and the new World Health Organization (\n                    <jats:styled-content style=\"fixed-case\">WHO<\/jats:styled-content>\n                    ) classification of renal cell tumours. This review aims to summarise the new information and evidence on several new and emerging\/provisional renal entities, which were mostly generated after the recent classification of renal neoplasia. We include in this review the following new and emerging\/provisional renal entities: succinate dehydrogenase\u2010deficient renal cell carcinoma, thyroid\u2010like follicular carcinoma of the kidney, anaplastic lymphoma kinase rearrangement\u2010associated renal cell carcinoma, renal cell carcinomas with prominent smooth muscle stroma, fumarate hydratase\u2010deficient renal cell carcinoma, biphasic squamoid papillary renal cell carcinoma, eosinophilic solid and cystic renal cell carcinoma, atrophic kidney\u2010like renal cell carcinoma, clear cell renal cell carcinoma with giant cells and emperipolesis, Warthin\u2010like papillary renal cell carcinoma, and low\u2010grade oncocytic renal tumour (\n                    <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>\n                    117\u2010negative; cytokeratin 7\u2010positive). Some of these entities, such as succinate dehydrogenase\u2010deficient renal cell carcinoma, have already been recognised as new entities in the\n                    <jats:styled-content style=\"fixed-case\">WHO<\/jats:styled-content>\n                    classification, and some have been recognised as provisional\/emerging entities. However, we include in this review several additional entities that, on the basis of the published evidence, also warrant this designation. We hope that this review will ease the navigation through this complex and evolving field, and will inform and stimulate new studies and discussions.\n                  <\/jats:p>","DOI":"10.1111\/his.13727","type":"journal-article","created":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T20:10:23Z","timestamp":1545163823000},"page":"31-59","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":137,"title":["New and emerging renal entities: a perspective post\u2010\n                    <scp>WHO<\/scp>\n                    2016 classification"],"prefix":"10.1111","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3142-8846","authenticated-orcid":false,"given":"Kiril","family":"Trpkov","sequence":"first","affiliation":[{"name":"University of Calgary and Calgary Laboratory Services Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3236-3127","authenticated-orcid":false,"given":"Ond\u0159ej","family":"Hes","sequence":"additional","affiliation":[{"name":"Charles University and University Hospital Pilsen Pilsen Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,18]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318299f2d1"},{"key":"e_1_2_15_3_1","volume-title":"World Health Organization classification of tumours of the urinary system and male genital organs","author":"Moch H","year":"2016"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1012357"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318227e7f4"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2009.12.005"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000292"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2014.86"},{"key":"e_1_2_15_9_1","first-page":"35","volume-title":"World Health Organization classification of tumours of the urinary system and male genital organs","author":"Gill A","year":"2016"},{"key":"e_1_2_15_10_1","first-page":"12188","article-title":"A novel germline mutation in SDHA identified in a rare case of gastrointestinal stromal tumor complicated with renal cell carcinoma","volume":"8","author":"Jiang Q","year":"2015","journal-title":"Int. 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