{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T13:12:21Z","timestamp":1778159541137,"version":"3.51.4"},"reference-count":53,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T00:00:00Z","timestamp":1659916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001469","name":"Singapore General Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001469","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>To describe a new international dataset for pathology reporting of ductal carcinoma <jats:italic>in\u2009situ<\/jats:italic> (DCIS), variants of lobular carcinoma <jats:italic>in\u2009situ<\/jats:italic> (LCIS) and low\u2010grade lesions (encapsulated papillary carcinoma, solid papillary carcinoma <jats:italic>in\u2009situ<\/jats:italic>, Paget's disease) produced by the International Collaboration on Cancer Reporting (ICCR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>The ICCR, a global alliance of pathology bodies, uses a rigorous and efficient process for the development of evidence\u2010based, structured datasets for pathology reporting of common cancers. Their aim is to support quality pathology reporting and engender understanding between the breast surgeon, pathologist, and oncologist for optimal and uniform patient management globally. Here we describe the dataset for DCIS, some variants of LCIS (namely the pleomorphic and the florid variants), and low\u2010grade lesions by a multidisciplinary panel of internationally recognized experts. The agreed dataset comprises 12 core (required) and five noncore (recommended) elements suitable for both developed and low\u2010income jurisdictions, derived from a review of current evidence. Areas of contention were addressed using a pragmatic approach in the absence of evidence. Use of all core elements is the minimum reporting standard for any individual case. Commentary is provided, explaining each element's clinical relevance, definitions to be applied where appropriate for the agreed list of value options and the rationale for considering the element as core or noncore.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This first internationally agreed dataset for DCIS, variants of LCIS, and low\u2010grade lesions reporting will enable their standardization of pathology reporting and enhance clinicopathological communication leading to improved patient outcomes. Widespread adoption will also facilitate international comparisons, multinational clinical trials, and help to improve the management of breast disease globally.<\/jats:p><\/jats:sec>","DOI":"10.1111\/his.14725","type":"journal-article","created":{"date-parts":[[2022,7,23]],"date-time":"2022-07-23T08:54:52Z","timestamp":1658566492000},"page":"467-476","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Dataset for pathology reporting of ductal carcinoma <i>in\u2009situ<\/i>, variants of lobular carcinoma <i>in\u2009situ<\/i> and low\u2010grade lesions: recommendations from the International Collaboration on Cancer Reporting (<scp>ICCR<\/scp>)"],"prefix":"10.1111","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7648-8896","authenticated-orcid":false,"given":"Stephen B","family":"Fox","sequence":"first","affiliation":[{"name":"Department of Pathology Peter MacCallum Cancer Centre, Level 4 Victorian Comprehensive Cancer Centre  Melbourne VIC Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fleur","family":"Webster","sequence":"additional","affiliation":[{"name":"International Collaboration on Cancer Reporting  Surry Hills NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih\u2010Jung","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Taichung Veterans General Hospital  Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boon","family":"Chua","sequence":"additional","affiliation":[{"name":"Prince of Wales Clinical School UNSW Sydney, The University of New South Wales  Randwick NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Collins","sequence":"additional","affiliation":[{"name":"Department of Pathology Beth Israel Deaconess Medical Center, 330 Brookline Ave, and Harvard Medical School  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maaria\u2010Pia","family":"Foschini","sequence":"additional","affiliation":[{"name":"Department Anatomic Pathology University of Bologna, Department of Biomedical and Neuromotor Sciences Unit of Anatomic Pathology at Bellaria Hospital  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Bruce Mann","sequence":"additional","affiliation":[{"name":"The Breast Service The Royal Melbourne Hospital  Parkville VIC Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewan","family":"Millar","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology NSW Heath Pathology St George Hospital, Kogarah NSW 2217 &amp; St George &amp; Sutherland Clinical School  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4167-8910","authenticated-orcid":false,"given":"Sarah E","family":"Pinder","sequence":"additional","affiliation":[{"name":"School of Cancer &amp; Pharmaceutical Sciences King's College London, 9th Floor, Innovation Hub, Comprehensive Cancer Centre at Guy's Hospital  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5009-5525","authenticated-orcid":false,"given":"Emad","family":"Rakha","sequence":"additional","affiliation":[{"name":"Department of Histopathology The University of Nottingham, Nottingham City Hospital  Nottingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abeer","family":"Shaaban","sequence":"additional","affiliation":[{"name":"Department of Cellular Pathology Queen Elizabeth Hospital Birmingham and Cancer and Genomic Sciences, University of Birmingham  Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7282-6440","authenticated-orcid":false,"given":"Benjamin Y","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology Singapore General Hospital  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9405-9665","authenticated-orcid":false,"given":"Gary","family":"Tse","sequence":"additional","affiliation":[{"name":"Department of Anatomical and Cellular Pathology Prince of Wales Hospital, The Chinese University of Hong Kong  Shatin Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Watson","sequence":"additional","affiliation":[{"name":"Department of Pathology, Biobanking and Biospecimen Research Services Deeley Research Centre, BC Cancer Agency  Canada Victoria British Columbia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1052-8605","authenticated-orcid":false,"given":"Puy Hoon","family":"Tan","sequence":"additional","affiliation":[{"name":"Division of Pathology Singapore General Hospital  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.4048\/jbc.2021.24.e5"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2012-0511-OA"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0b013e31825d808b"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.12042"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31829d7f35"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.PAT.0000426752.37463.b8"},{"key":"e_1_2_8_8_1","unstructured":"International Collaboration on Cancer Reporting.Invasive carcinoma of the breast histopathology reporting guide. 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