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The majority of primary pulmonary salivary gland\u2010type tumours are malignant, with the most common entities being mucoepidermoid carcinoma, adenoid cystic carcinoma, and epithelial\u2010myoepithelial carcinoma. Less commonly seen are myoepithelial carcinoma, hyalinizing clear cell carcinoma, acinic cell carcinoma, secretory carcinoma, salivary duct carcinoma, intraductal carcinoma, and polymorphous adenocarcinoma. Benign salivary gland\u2010type tumours of the lung include pleomorphic adenoma and sialadenoma papilliferum. Morphologic, immunophenotypic, and molecular features of these neoplasms are largely similar to salivary gland tumours elsewhere, and therefore the exclusion of metastatic disease requires clinical and radiologic correlation. However, the differential diagnostic considerations are different in the lung. The distinction of salivary gland\u2010type tumours from their histologic mimics is important for both prognostication and treatment decisions. Overall, salivary gland type\u2010tumours tend to have a more favourable outcome than other pulmonary carcinomas, although high\u2010grade variants exist for many of these tumour types. Recent advances in our understanding of the spectrum of salivary gland\u2010type tumours reported in the lung and their diversity of molecular and immunohistochemical features have helped to refine the classification of these tumours and have highlighted a few differences between salivary gland\u2010type tumours of the lung and those primary to other sites.<\/jats:p>","DOI":"10.1111\/his.15039","type":"journal-article","created":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T11:03:20Z","timestamp":1694430200000},"page":"102-123","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Recent developments in the pathology of primary pulmonary salivary gland\u2010type tumours"],"prefix":"10.1111","volume":"84","author":[{"given":"Julia R","family":"Naso","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine and Pathology Mayo Clinic Rochester Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8948-4758","authenticated-orcid":false,"given":"Anja C","family":"Roden","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology Mayo Clinic Rochester Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,11]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2021.03.001"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.14733"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2018.00153"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/10668969221137516"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.12.9579"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2014.72"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23048"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2018.11.010"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.1749"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/9742091"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/lungindia.lungindia_284_18"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3182a7d272"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0000000000000656"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13000-022-01216-5"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2014.11.010"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.32074\/1591-951X-786"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000032871"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/1066896919836499"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-021-01351-8"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.21037\/gs-22-709"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/1066896920914975"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2017.10.027"},{"key":"e_1_2_13_24_1","article-title":"Primary lung secretory carcinoma: a case report","volume":"5","author":"Li H","year":"2021","journal-title":"Prec. 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