{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:06:41Z","timestamp":1790716001684,"version":"4.1.0"},"reference-count":55,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:00:00Z","timestamp":1721260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      Ductal carcinoma\n                      <jats:italic>in situ<\/jats:italic>\n                      (DCIS) is recognised by the World Health Organisation (WHO) Classification of Tumours (WCT) as a non\u2010invasive neoplastic epithelial proliferation confined to the mammary ducts and lobules. This report categorises the references cited in the DCIS chapter of the 5th edition of the WCT (Breast Tumours) according to prevailing evidence levels for evidence\u2010based medicine and the Hierarchy of Evidence for Tumour Pathology (HETP), identifying potential gaps that can inform subsequent editions of the WCT for this tumour.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We included all citations from the DCIS chapter of the WCT (Breast Tumours, 5th edition). Each citation was appraised according to its study design and evidence level. We developed our map of cited evidence, which is a graphical matrix of tumour type (column) and tumour descriptors (rows). Spheres were used to represent the evidence, with size and colour corresponding to their number and evidence level respectively. Thirty\u2010six publications were retrieved. The cited literature in the DCIS chapter comprised mainly case series and were regarded as low\u2010level. We found an unequal distribution of citations among tumour descriptors. \u2018Pathogenesis\u2019 and \u2018prognosis and prediction\u2019 contained the most references, while \u2018clinical features\u2019, \u2018aetiology\u2019 and \u2018diagnostic molecular pathology\u2019 had only a single citation each. \u2018Prognosis and prediction\u2019 had the greatest proportion of moderate\u2010 and high\u2010levels of evidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings align with the disposition for observational studies inherent in the field of pathology. Our map is a springboard for future efforts in mapping all available evidence on DCIS, potentially augmenting the editorial process and future editions of WCTs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/his.15279","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T19:58:43Z","timestamp":1721332723000},"page":"510-520","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Mapping the cited evidence of ductal carcinoma\n                    <i>in situ<\/i>\n                    from the 5th edition of the World Health Organisation classification of tumours of the breast"],"prefix":"10.1111","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9519-7317","authenticated-orcid":false,"given":"Clarissa Jing Wen","family":"Wong","sequence":"first","affiliation":[{"name":"Yong Loo Lin School of Medicine, National University of Singapore  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2719-1449","authenticated-orcid":false,"given":"Nur Diyana","family":"Md Nasir","sequence":"additional","affiliation":[{"name":"Singapore Breast Surgery Center  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5854-1438","authenticated-orcid":false,"given":"Valerie Cui Yun","family":"Koh","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology Singapore General Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona","family":"Campbell","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University  Newcastle Upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7648-8896","authenticated-orcid":false,"given":"Stephen","family":"Fox","sequence":"additional","affiliation":[{"name":"Department of Pathology, Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology University of Melbourne  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil R","family":"Lakhani","sequence":"additional","affiliation":[{"name":"University of Queensland Centre for Clinical Research and Pathology Queensland  Brisbane QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nickolas","family":"Myles","sequence":"additional","affiliation":[{"name":"International Agency for Research on Cancer (IARC), World Health Organisation  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Yip","sequence":"additional","affiliation":[{"name":"Department of Anatomy Yong Loo Lin School of Medicine, National University of Singapore  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6344-9081","authenticated-orcid":false,"given":"Richard","family":"Colling","sequence":"additional","affiliation":[{"name":"Nuffield Department of Surgical Sciences University of Oxford, John Radcliffe Hospital  Oxford UK"},{"name":"Department of Cellular Pathology Oxford University Hospitals NHS Foundation Trust  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian A","family":"Cree","sequence":"additional","affiliation":[{"name":"International Agency for Research on Cancer (IARC), World Health Organisation  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilani","family":"Lokuhetty","sequence":"additional","affiliation":[{"name":"International Agency for Research on Cancer (IARC), World Health Organisation  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1052-8605","authenticated-orcid":false,"given":"Puay Hoon","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Anatomy Yong Loo Lin School of Medicine, National University of Singapore  Singapore Singapore"},{"name":"Luma Medical Centre  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,18]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Breast tumours","author":"WHO Classification of Tumours Editorial Board","year":"2019"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.32975"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.14648"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33260"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2022-061240"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.modpat.2023.100357"},{"key":"e_1_2_10_8_1","unstructured":"WhiteH.The strategic use of evidence and gap maps to build evidence architecture.Centre of Excellence for Development Impact and Learning (CEDIL).2021. [Accessed May 27 2023]. Available at:https:\/\/cedilprogramme.org\/publications\/cedil\u2010methods\u2010working\u2010paper\u20105\/."},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-023-02178-5"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.4073\/cmdp.2018.2"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2016.05.015"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001603"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.13837"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1590\/0100-3984.2018.0058"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-019-0204-1"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/jncimonographs\/lgq027"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-015-0586-z"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molonc.2013.07.005"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/jclinpath-2018-205484"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2019.01229"},{"key":"e_1_2_10_21_1","first-page":"48","article-title":"Radioactive seed localization and wire guided localization in breast cancer: a systematic review and meta\u2010analysis","volume":"24","author":"Wang G","year":"2019","journal-title":"J. B.U.ON."},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djp482"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000001397"},{"key":"e_1_2_10_24_1","unstructured":"HowickJ ChalmersI GlasziouPet\u00a0al.Explanation of the 2011 oxford centre for evidence\u2010based medicine (ocebm) levels of evidence (background document).Oxford Centre for Evidence\u2010Based Medicine.2011. [Accessed May 8 2022]. Available at:https:\/\/www.cebm.ox.ac.uk\/resources\/levels\u2010ofevidence\/ocebm\u2010levels\u2010of\u2010evidence."},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.14856"},{"key":"e_1_2_10_26_1","volume-title":"Eppi\u2010reviewer: advanced software for systematic reviews, maps and evidence synthesis","author":"Thomas J","year":"2022"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/cl2.1125"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.11613\/BM.2012.031"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pathol.4.110807.092306"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3700403"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3700511"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2006.01.005"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2014-0106-RA"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2014-0461-OA"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-021-00796-9"},{"key":"e_1_2_10_36_1","first-page":"85","article-title":"Breast cancer: a review of the literature","volume":"35","author":"Richie RC","year":"2003","journal-title":"J. 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