{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T04:35:03Z","timestamp":1791866103571,"version":"4.3.4"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>To use the Delphi consensus methodology to establish standardized criteria for the histopathological diagnosis of adenomyosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Between April and September 2024, a modified three\u2010round Delphi consensus study was conducted. Thirty\u2010one gynaecological pathologists from 18 countries participated in surveys to evaluate and refine a diagnostic framework for adenomyosis in hysterectomy specimens. Key areas achieving the highest level of agreement included: 4\u20136 blocks for routine histopathological examination of hysterectomy specimens with benign indications; defining adenomyosis as endometrial glands and\/or stroma greater than 2\u2009mm into the myometrium or more than one\u2010third of myometrial thickness; that the absolute number of glands or stromal tissue does not contribute to the diagnosis of adenomyosis; a single gland or stromal focus can be diagnostic; and definitions of focal, extensive, superficial and deep adenomyosis. In total, 93% of respondents were in favour of standardizing the diagnosis to reduce inter\u2010pathologist variability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study proposes the first consensus\u2010based guideline for the histopathological diagnosis of adenomyosis. Supported by the responses of 31 international experts through a modified Delphi method, this framework provides pathologists with clear diagnostic criteria. Further research should correlate these criteria with clinical symptoms and outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/his.15480","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T07:25:12Z","timestamp":1750404312000},"page":"446-452","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Standardizing the histopathological diagnosis of adenomyosis: an international Delphi consensus"],"prefix":"10.1111","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0987-4401","authenticated-orcid":false,"given":"Tristan","family":"McCaughey","sequence":"first","affiliation":[{"name":"The Royal Women's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marsali","family":"Newman","sequence":"additional","affiliation":[{"name":"The Mercy Hospital for Women  Melbourne Victoria Australia"},{"name":"Austin Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonie","family":"Constable","sequence":"additional","affiliation":[{"name":"Melbourne Pathology  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0790-637X","authenticated-orcid":false,"given":"Fatima","family":"Figueiredo","sequence":"additional","affiliation":[{"name":"The Royal Women's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5742-9148","authenticated-orcid":false,"given":"Samantha S","family":"Mooney","sequence":"additional","affiliation":[{"name":"The Mercy Hospital for Women  Melbourne Victoria Australia"},{"name":"The Department of Obstetrics, Gynaecology &amp; 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