{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T23:57:32Z","timestamp":1789603052215,"version":"build-2803163510"},"reference-count":71,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Testicular sex cord\u2010stromal tumours (TSCSTs) are relatively rare, accounting for ~5% of all testicular neoplasms. They were historically classified into Leydig cell tumour, Sertoli cell tumour, granulosa cell tumour, and unclassified sex cord\u2010stromal tumour. More recently, classification was expanded to incorporate additional histologic types, including some associated with inherited cancer predisposition syndromes. However, the classification of TSCSTs still relies entirely on morphology, with some tumour types being defined based on their resemblance to ovarian counterparts. In recent years, molecular studies have identified drivers and genomic alterations associated with aggressive behaviour and progression; however, these findings have not yet impacted classification and management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Under sponsorship of the International Society of Urological Pathology (ISUP) and the Genitourinary Pathology Society (GUPS), a group of genitourinary pathologists was assembled in 2023 with the aim of assessing how to use these new data to improve the classification and management of TSCSTs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      This paper summarizes the recommendations derived from the consensus activities and the first meeting of the\n                      <jats:italic>te<\/jats:italic>\n                      sticular\n                      <jats:italic>s<\/jats:italic>\n                      ex cord\u2010\n                      <jats:italic>s<\/jats:italic>\n                      tromal\n                      <jats:italic>t<\/jats:italic>\n                      umour (TESST) group (held at Johns Hopkins Hospital, Baltimore, USA, 3\/23\/2024).\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/his.15482","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T04:27:14Z","timestamp":1750220834000},"page":"660-676","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Assessment and classification of sex cord\u2010stromal tumours of the testis: recommendations from the testicular sex cord\u2010stromal tumour (\n                    <scp>TESST<\/scp>\n                    ) group, an Expert Panel of the Genitourinary Pathology Society (\n                    <scp>GUPS<\/scp>\n                    ) and International Society of Urological Pathology (\n                    <scp>ISUP<\/scp>\n                    )"],"prefix":"10.1111","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8817-6331","authenticated-orcid":false,"given":"Andres M","family":"Acosta","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Indiana University School of Medicine and Indiana University Health Partners  Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Colecchia","sequence":"additional","affiliation":[{"name":"Department of Pathology Vita Salute San Raffaele University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8488-543X","authenticated-orcid":false,"given":"Eva","family":"Comperat","sequence":"additional","affiliation":[{"name":"Department of 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