{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T03:41:51Z","timestamp":1773114111107,"version":"3.50.1"},"reference-count":42,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Hepatoblastoma is the most common primary malignant tumour of the liver diagnosed in children and its incidence is increasing worldwide. Ongoing international clinical trials and scientific collaborative efforts are attempting to standardize the diagnosis, risk stratification and management of young patients diagnosed with this rare cancer, which includes surgical resection of the tumour. Here we report the international consensus\u2010based dataset for the pathology reporting of hepatoblastoma resection specimens. The dataset was developed under the auspices of the International Collaboration on Cancer Reporting (ICCR), a global alliance of international pathology and cancer organizations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>According to the ICCR's guidelines for dataset development, an international expert panel including paediatric pathologists and a paediatric oncologist specialized in liver tumours developed a set of core and non\u2010core data items for hepatoblastoma resection specimens based on critical review and discussion of current evidence available. Members of the panel were specialists working in tertiary paediatric hospitals, central reviewers for international paediatric liver tumours consortia and\/or involved in paediatric liver tumour trials expert committees. Commentaries were provided to support each data item, explaining the rationale for selecting them as a \u2018core\u2019 or \u2018non\u2010core\u2019 elements, their clinical relevance and highlighting potential areas of lack of evidence, including clinical, macroscopic, microscopic and ancillary testing considerations. The hepatoblastoma dataset was finalized and ratified following international public consultation and is published on the ICCR website for wide implementation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This is the first international dataset developed by an international expert panel for reporting hepatoblastoma resection specimens aimed to promote high\u2010quality, standardized pathology reporting of these rare paediatric liver tumours. The adoption and implementation of this hepatoblastoma data set, freely available worldwide on the ICCR website (\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.iccr-cancer.org\/data-sets\">www.iccr\u2010cancer.org\/data\u2010sets<\/jats:ext-link>\n                      ), will facilitate accurate reporting and enhance the consistency of data collection, support retrospective and inform prospective research and ultimately help to improve clinical outcomes of children with hepatoblastoma.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/his.15536","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T08:15:12Z","timestamp":1755677712000},"page":"802-814","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pathology reporting of hepatoblastoma resections: recommendations from the international collaboration on cancer reporting"],"prefix":"10.1111","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6584-420X","authenticated-orcid":false,"given":"Dolores H","family":"L\u00f3pez\u2010Terrada","sequence":"first","affiliation":[{"name":"Department of Pathology Texas Children's Hospital  Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8706-0388","authenticated-orcid":false,"given":"Fleur","family":"Webster","sequence":"additional","affiliation":[{"name":"International Collaboration on Cancer Reporting  Surry Hills NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3915-3816","authenticated-orcid":false,"given":"Rita","family":"Alaggio","sequence":"additional","affiliation":[{"name":"Pathology Unit, Department of Laboratories Bambino Gesu Children's Hospital IRCCS  Rome Italy"},{"name":"Italy\/Universit\u00e0 Sapienza  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9432-2390","authenticated-orcid":false,"given":"Jonathan W","family":"Bush","sequence":"additional","affiliation":[{"name":"Department of Pathology University of British Columbia  Vancouver BC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6324-6858","authenticated-orcid":false,"given":"Soo\u2010Jin","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Pathology University of California San Francisco  San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6871-1296","authenticated-orcid":false,"given":"Ronald R","family":"de Krijger","sequence":"additional","affiliation":[{"name":"Department of Pathology University Medical Center Utrecht, Princess Maxima Center for Pediatric Oncology  Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6242-6400","authenticated-orcid":false,"given":"Takeshi","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Pathology Osaka City General Hospital  Osaka City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8957-3870","authenticated-orcid":false,"given":"Allison F","family":"O'Neill","sequence":"additional","affiliation":[{"name":"Department of Pediatric Oncology Dana\u2010Farber Cancer Institute\/Boston Children's Cancer and Blood Disorders Center and Harvard Medical School  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8036-6288","authenticated-orcid":false,"given":"Antonio R","family":"Perez\u2010Atayde","sequence":"additional","affiliation":[{"name":"Department of Pathology Boston Children's Hospital and Harvard Medical School  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6214-9167","authenticated-orcid":false,"given":"Sarangarajan","family":"Ranganathan","sequence":"additional","affiliation":[{"name":"Division of Pathology and Laboratory Medicine Cincinnati Children's Hospital Medical Center  Cincinnati OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2234-0271","authenticated-orcid":false,"given":"Jens","family":"Stahlschmidt","sequence":"additional","affiliation":[{"name":"Department of Histopathology and Molecular Pathology St James's University Hospital, Leeds Teaching Hospitals NHS Trust  Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1145-5249","authenticated-orcid":false,"given":"Yukichi","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Pathology Kanagawa Children's Medical Center  Yokohama 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