{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T22:04:25Z","timestamp":1789596265950,"version":"build-2803163510"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>To summarise the content and significance of the recently published second edition International Collaboration on Cancer Reporting (ICCR) histopathology dataset for testicular germ cell tumours, covering the Orchiectomy specimen dataset. We highlight key updates from the first editions, including alignment with the 5th edition World Health Organization (WHO) Classification, revised staging criteria, clarified core data elements versus non\u2010core elements and the evidentiary basis underpinning these changes. A review of the ICCR 2nd edition dataset for Orchiectomy specimens of primary testicular tumours was performed, focusing on their development by an international expert committee using a consensus\u2010based approach. Core (required) and non\u2010core (recommended) data elements were identified along with the level of evidence supporting each, following National Health and Medical Research Council (NHMRC) criteria. Changes from the first edition were extracted by comparing dataset content and notes, informed by up\u2010to\u2010date literature through July 2024. The 2nd edition Orchiectomy dataset provides an integrated, harmonised framework for reporting testicular germ cell tumours. The dataset incorporates the WHO 5th Edition Classification of Urinary and Male Genital Tumours. Pathological staging criteria have been updated to align with the 8th edition Union for International Cancer Control (UICC)\/American Joint Committee on Cancer (AJCC) tumour\u2010node\u2010metastasis (TNM) definitions. The second edition of this dataset includes changes to align the dataset with the WHO Classification of Tumours, Urinary and Male Genital Tumours, 5th edition, 2022. The ICCR dataset includes the 5th edition Corrigenda, July 2024. It was agreed that this dataset is not suitable for non\u2010germ cell tumours, with the hope that a new dataset, especially for sex\u2010cord stromal tumours, would be developed. The 2nd edition Orchiectomy dataset represents an authoritative, up\u2010to\u2010date standard for pathology reporting of primary testicular germ cell tumours. By incorporating the WHO 5th edition classifications, current TNM staging and the latest evidence on prognostic factors, this dataset facilitates uniform reporting and prognostication. The ICCR dataset underscores core data required for patient management decisions (e.g., adjuvant therapy in Stage I disease, post\u2010chemotherapy management) while providing flexibility through non\u2010core elements for additional useful information. Adoption of this internationally vetted dataset will enhance consistency, assist multidisciplinary treatment planning and align pathology reports with modern consensus guidelines and classifications. The dataset can be used in both high\u2010resource and limited\u2010resource settings without compromising the essential reporting standards.<\/jats:p>","DOI":"10.1111\/his.70041","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T13:23:30Z","timestamp":1765545810000},"page":"252-264","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Second edition\n                    <scp>ICCR<\/scp>\n                    dataset for testicular germ cell tumours: a reporting guide for histopathological diagnosis of orchiectomy specimens"],"prefix":"10.1111","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0367-6527","authenticated-orcid":false,"given":"Felix","family":"Bremmer","sequence":"first","affiliation":[{"name":"Institute of Pathology University Medical Center G\u00f6ttingen  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8706-0388","authenticated-orcid":false,"given":"Fleur","family":"Webster","sequence":"additional","affiliation":[{"name":"International Collaboration on Cancer Reporting  Surry Hills NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gedske","family":"Daugaard","sequence":"additional","affiliation":[{"name":"Department of Oncology Copenhagen University Hospital, Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Princess Margaret Cancer Centre  Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6611-6389","authenticated-orcid":false,"given":"Muhammad T.","family":"Idrees","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Indiana University School of Medicine  Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia\u2010Sui","family":"Kao","sequence":"additional","affiliation":[{"name":"Diagnostics Institute, Laboratory Medicine\u2014Anatomic Pathology, Cleveland Clinic  Cleveland OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1776-3541","authenticated-orcid":false,"given":"Kosuke","family":"Miyai","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine National Defense Medical College Hospital  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Rosaria","family":"Raspollini","sequence":"additional","affiliation":[{"name":"Department of Histopathology and Molecular Diagnostics Careggi University Hospital  Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Srigley","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathobiology University of Toronto  Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satish","family":"Tickoo","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asli","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Department of Pathology, Calgary Laboratory Services University of Calgary  Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0256-0074","authenticated-orcid":false,"given":"Thomas","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department of Pathology Copenhagen University Hospital, Herlev and Gentofte Hospital  Herlev Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5474-8696","authenticated-orcid":false,"given":"Daniel M.","family":"Berney","sequence":"additional","affiliation":[{"name":"Centre of Cancer Biomarkers and Biotherapeutics, Barts Cancer Institute Queen Mary University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.12657"},{"key":"e_1_2_10_3_1","volume-title":"Urinary and male genital tumours","author":"WHO Classification of Tumours Editorial Board","year":"2022"},{"key":"e_1_2_10_4_1","volume-title":"Urinary and male genital tumours","author":"WHO Classification of Tumours Editorial 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