{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T14:22:51Z","timestamp":1780496571830,"version":"3.54.1"},"reference-count":212,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>We present an update on the molecular pathology of prostate cancer, including its molecular classification, key driver gene and other somatic alterations, as well as current concepts around biomarker testing, with an emphasis on information pertinent to the surgical\u00a0pathologist for their daily practice and communications with clinicians. For in depth coverage of the molecular and clinical features of potential prostate cancer precursors, including high grade prostatic intraepithelial neoplasia, the readers are directed to recent publications.<\/jats:p>","DOI":"10.1111\/his.70133","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T07:59:42Z","timestamp":1775548782000},"page":"3-25","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The molecular pathology of prostate cancer: an update for practising pathologists"],"prefix":"10.1111","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4087-3186","authenticated-orcid":false,"given":"Fernanda","family":"Caramella Pereira","sequence":"first","affiliation":[{"name":"Department of Pathology, Urology and Oncology The Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4847-5307","authenticated-orcid":false,"given":"Angelo M","family":"De Marzo","sequence":"additional","affiliation":[{"name":"Department of Pathology, Urology and Oncology The Johns Hopkins University School of Medicine  Baltimore Maryland USA"},{"name":"The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins  Baltimore Maryland USA"},{"name":"The Brady Urological Research Institute at Johns Hopkins  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a030403","article-title":"Molecular pathology of high\u2010grade prostatic intraepithelial neoplasia: challenges and opportunities","volume":"9","author":"Trabzonlu L","year":"2018","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000002430"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21871"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2002-0032"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2022.4319"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djaa068"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2015.09.033"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41391-023-00702-1"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.0228"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semradonc.2025.04.009"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2510310"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers17020215"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14143302"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euo.2025.04.002"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11684-022-0939-9"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.15669"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.75.3657"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040720"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-13-0568"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.122.8.2475"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2009.10.020"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1110000"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0164233"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.22552"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-021-01622-4"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.23747"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2006.07.014"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1808"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-09-0387"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.24400"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.00915"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41698-025-00847-3"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1603144"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-0370"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2013.193"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/genes13101692"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2025.05.021"},{"key":"e_1_2_12_40_1","unstructured":"SchaefferE SrinivasS AntonarakisSE.National Comprehensive Cancer Network (NCCN) Prostate Cancer Guidelines 2021.2021."},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2020.06.011"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.00046"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1200\/OP-24-00626"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.10.025"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0078-z"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI147878"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.path.2022.08.002"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41585-020-00400-w"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800769"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmoldx.2017.01.007"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000213424.38503.aa"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2016.04.017"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800981"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2018976118"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2022.01.009"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1117679"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.03.021"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.613"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.11.019"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-025-02289-w"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2008.111"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(03)00197-1"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-51450-2"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-020-00125-0"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI162396"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2018.00377"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11081076"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1177\/1947601911407325"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pathol.4.110807.092311"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2018.9"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1038\/pcan.2013.8"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI70354"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2014.10.027"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-3280"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-24-1206"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-20820-x"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-0476"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abd9208"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.09207"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2017.08.027"},{"key":"e_1_2_12_81_1","first-page":"58","article-title":"Alterations in AR\u2010FOXA1 signaling in prostate cancer progression and therapeutic resistance","volume":"6","author":"Gao S","year":"2025","journal-title":"J. Natl. Cancer Cent."},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0495-401"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1315815"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13238-020-00786-8"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1347-4"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1318-9"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-24-3471"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-019-0203-2"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-019-0204-1"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2016.09.003"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-20-2371"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2020.03.024"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2024.101758"},{"key":"e_1_2_12_94_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-24-0400"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2011.546"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-018-2225-7"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.modpat.2023.100146"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.modpat.2024.100616"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cancergen.2014.09.003"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2010.05.026"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-32656-2_5"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3315"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.20543"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2011.590"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41417-020-00288-z"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-12-1342"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-025-00952-z"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1177\/1947601910379132"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2016.63"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmoldx.2021.05.006"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdv356"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13671"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.06.039"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15092435"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.746102"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1177\/17588359231221337"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1911440"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI132031"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-20-3708"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-20-0764"},{"key":"e_1_2_12_121_1","doi-asserted-by":"publisher","DOI":"10.1200\/PO.17.00029"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3878"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2018.10.009"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-23-3403"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan6733"},{"key":"e_1_2_12_126_1","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a030445","article-title":"Prostate cancer epigenetics: from basic mechanisms to clinical implications","volume":"9","author":"Yegnasubramanian S","year":"2018","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1155\/2007\/356742"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41585-024-00991-8"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3005211"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12022-025-09871-2"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2014.21"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-24-2061"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2018.22"},{"key":"e_1_2_12_134_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-13-1982"},{"key":"e_1_2_12_135_1","first-page":"1","article-title":"The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1","volume":"5","author":"Romero R","year":"2024","journal-title":"Nat. Can."},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aav0891"},{"key":"e_1_2_12_137_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2322203121"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.5781"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0000000000001308"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(95)90041-1"},{"key":"e_1_2_12_141_1","first-page":"111","article-title":"Benign mimics of prostatic adenocarcinoma on needle biopsy","volume":"2","author":"Gaudin PB","year":"1997","journal-title":"Anat. Pathol."},{"key":"e_1_2_12_142_1","unstructured":"Biopsy Interpretation of the Prostate.2021."},{"key":"e_1_2_12_143_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198905000-00006"},{"key":"e_1_2_12_144_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/107.2.219"},{"key":"e_1_2_12_145_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200209000-00006"},{"key":"e_1_2_12_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(01)01311-5"},{"key":"e_1_2_12_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2006.08.016"},{"key":"e_1_2_12_148_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200111000-00007"},{"key":"e_1_2_12_149_1","first-page":"2220","article-title":"Alpha\u2010methylacyl\u2010CoA racemase: A new molecular marker for prostate cancer","volume":"62","author":"Luo J","year":"2002","journal-title":"Cancer Res."},{"key":"e_1_2_12_150_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.13.1662"},{"key":"e_1_2_12_151_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200308000-00010"},{"key":"e_1_2_12_152_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200402000-00012"},{"key":"e_1_2_12_153_1","doi-asserted-by":"publisher","DOI":"10.1309\/1G1NK9DBGFNB792L"},{"key":"e_1_2_12_154_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPGFJP83IXZEUR"},{"key":"e_1_2_12_155_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2017.139"},{"key":"e_1_2_12_156_1","doi-asserted-by":"publisher","DOI":"10.1038\/pcan.2010.23"},{"key":"e_1_2_12_157_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000205"},{"key":"e_1_2_12_158_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000238"},{"key":"e_1_2_12_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2012.06.024"},{"key":"e_1_2_12_160_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318215cc03"},{"key":"e_1_2_12_161_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPK1OV6IMNPFGL"},{"key":"e_1_2_12_162_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.22836"},{"key":"e_1_2_12_163_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0000000000000431"},{"key":"e_1_2_12_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2013.05.005"},{"key":"e_1_2_12_165_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181e6cbf3"},{"key":"e_1_2_12_166_1","first-page":"182","article-title":"NKX3.1 and PSMA are sensitive diagnostic markers for prostatic carcinoma in bone metastasis after decalcification of specimens","volume":"6","author":"Huang H","year":"2018","journal-title":"Am. J. Clin. Exp. Urol."},{"key":"e_1_2_12_167_1","doi-asserted-by":"publisher","DOI":"10.4132\/jptm.2016.06.14"},{"key":"e_1_2_12_168_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31802f5d33"},{"key":"e_1_2_12_169_1","first-page":"16","article-title":"Expression of NKX3.1, prostatic specific antigen and prostatic specific alkaline phosphatase in cytology specimens of metastatic prostatic carcinoma","volume":"1","author":"Wang M","year":"2021","journal-title":"J. Clin. Transl. Pathol."},{"key":"e_1_2_12_170_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2009-0034"},{"key":"e_1_2_12_171_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-1596-2-41"},{"key":"e_1_2_12_172_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.20043"},{"key":"e_1_2_12_173_1","doi-asserted-by":"publisher","DOI":"10.5858\/2007-131-599-DPFCAO"},{"key":"e_1_2_12_174_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3180536678"},{"key":"e_1_2_12_175_1","first-page":"1807","article-title":"Expression of the prostate\u2010specific membrane Antigen1","volume":"54","author":"Israeli RS","year":"1994","journal-title":"Cancer Res."},{"key":"e_1_2_12_176_1","first-page":"81","article-title":"Prostate\u2010specific membrane antigen expression in normal and malignant human tissues","volume":"3","author":"Silver DA","year":"1997","journal-title":"Clin. Cancer Res."},{"key":"e_1_2_12_177_1","first-page":"2674","article-title":"Prostate\u2010specific membrane antigen is produced in tumor\u2010associated neovasculature","volume":"5","author":"Chang SS","year":"1999","journal-title":"Clin. Cancer Res."},{"key":"e_1_2_12_178_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-025-01686-y"},{"key":"e_1_2_12_179_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.02.013"},{"key":"e_1_2_12_180_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2017.05.004"},{"key":"e_1_2_12_181_1","doi-asserted-by":"publisher","DOI":"10.1038\/pcan.2016.12"},{"key":"e_1_2_12_182_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(98)90199-X"},{"key":"e_1_2_12_183_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-019-0268-y"},{"key":"e_1_2_12_184_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.24174"},{"key":"e_1_2_12_185_1","doi-asserted-by":"publisher","DOI":"10.1038\/pcan.2008.47"},{"key":"e_1_2_12_186_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2013.12.001"},{"key":"e_1_2_12_187_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-021-00745-6"},{"key":"e_1_2_12_188_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djaa201"},{"key":"e_1_2_12_189_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2018-0068-OA"},{"key":"e_1_2_12_190_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-016-1904-2"},{"key":"e_1_2_12_191_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2017.03.004"},{"key":"e_1_2_12_192_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/91.18.1574"},{"key":"e_1_2_12_193_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.27954"},{"key":"e_1_2_12_194_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2016.10.013"},{"key":"e_1_2_12_195_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1411446111"},{"key":"e_1_2_12_196_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41391-023-00766-z"},{"key":"e_1_2_12_197_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0066855"},{"key":"e_1_2_12_198_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0000000000000419"},{"key":"e_1_2_12_199_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70295-3"},{"key":"e_1_2_12_200_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2014.05.004"},{"key":"e_1_2_12_201_1","doi-asserted-by":"publisher","DOI":"10.1200\/PO.20.00325"},{"key":"e_1_2_12_202_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2024.0019"},{"key":"e_1_2_12_203_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.02768"},{"key":"e_1_2_12_204_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers17142334"},{"key":"e_1_2_12_205_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2019.1734"},{"key":"e_1_2_12_206_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-021-01669-3"},{"issue":"1","key":"e_1_2_12_207_1","article-title":"Racial disparity in the genomics of precision oncology of prostate cancer","volume":"6","author":"Le T","year":"2023","journal-title":"Cancer Rep."},{"key":"e_1_2_12_208_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.70020"},{"key":"e_1_2_12_209_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euo.2024.01.004"},{"key":"e_1_2_12_210_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-022-00613-w"},{"key":"e_1_2_12_211_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-24-3656"},{"key":"e_1_2_12_212_1","doi-asserted-by":"publisher","DOI":"10.1200\/PO.24.00145"},{"key":"e_1_2_12_213_1","doi-asserted-by":"publisher","DOI":"10.1200\/CCI-24-00284"}],"container-title":["Histopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/his.70133","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/his.70133","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/his.70133","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T13:43:57Z","timestamp":1780494237000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/his.70133"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,7]]},"references-count":212,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/his.70133"],"URL":"https:\/\/doi.org\/10.1111\/his.70133","archive":["Portico"],"relation":{},"ISSN":["0309-0167","1365-2559"],"issn-type":[{"value":"0309-0167","type":"print"},{"value":"1365-2559","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,7]]},"assertion":[{"value":"2026-04-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}