{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T02:30:03Z","timestamp":1785551403543,"version":"3.56.0"},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,4,16]],"date-time":"2013-04-16T00:00:00Z","timestamp":1366070400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Anal cancer is more common in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive homosexual men than in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010negative homosexual men and the general population. Earlier diagnosis leads to improved prognosis. We aimed to determine if regular anal inspection and digital examination of asymptomatic homosexual men attending for routine <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> care were acceptable and to record the rate of referral for diagnosis of potentially malignant anal lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We offered anal examinations to consecutive homosexual men with <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> infection aged\u2009\u2265\u200935 years during their routine <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> clinic visits, aiming to complete three examinations over a 12\u2010month period. Acceptability questionnaires were completed at baseline and after each examination and doctors recorded examination findings and all resulting interventions. Hospital referral outcomes were collected and interventions were costed using the Australian Medical Benefits Schedule.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 142 men who were offered enrolment in the study, 102 [72%; 95% confidence interval (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) 64\u201379%] participated. Following the initial anal examinations, four men were referred to surgeons. Cancer was excluded in three men (3%; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1\u20138%) and one was diagnosed with anal squamous cell carcinoma (<jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content>). Three men had anoscopy performed at the time and two were referred for colonoscopy. Ninety\u2010eight per cent (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 93\u2013100%) of respondents said that they would probably have the examination next time. The intervention was estimated to cost approximately Australian $16 per examination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Regular anal digital examinations are an acceptable and inexpensive addition to the routine care of homosexual men with <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> infection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.12035","type":"journal-article","created":{"date-parts":[[2013,4,17]],"date-time":"2013-04-17T03:13:29Z","timestamp":1366168409000},"page":"491-496","source":"Crossref","is-referenced-by-count":23,"title":["Acceptability of digital anal cancer screening examinations in <scp>HIV<\/scp>\u2010positive homosexual men"],"prefix":"10.1111","volume":"14","author":[{"given":"TRH","family":"Read","sequence":"first","affiliation":[{"name":"Melbourne Sexual Health Centre Alfred Health  Melbourne Australia"},{"name":"Melbourne School of Population Health University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Vodstrcil","sequence":"additional","affiliation":[{"name":"Melbourne Sexual Health Centre Alfred Health  Melbourne Australia"},{"name":"Melbourne School of Population Health University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AE","family":"Grulich","sequence":"additional","affiliation":[{"name":"Kirby Institute University of New South Wales  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Farmer","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Alfred Hospital  Melbourne Australia"},{"name":"Department of Surgery Monash University  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CS","family":"Bradshaw","sequence":"additional","affiliation":[{"name":"Melbourne Sexual Health Centre Alfred Health  Melbourne Australia"},{"name":"Melbourne School of Population Health University of Melbourne  Melbourne Australia"},{"name":"Department of Epidemiology and Preventive Medicine Monash University  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MY","family":"Chen","sequence":"additional","affiliation":[{"name":"Melbourne Sexual Health Centre Alfred Health  Melbourne Australia"},{"name":"Melbourne School of Population Health University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Tabrizi","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Infectious Diseases The Royal Women's Hospital  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JS","family":"Hocking","sequence":"additional","affiliation":[{"name":"Centre for Women's Health, Gender and Society University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Anderson","sequence":"additional","affiliation":[{"name":"Kirby Institute University of New South Wales  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CK","family":"Fairley","sequence":"additional","affiliation":[{"name":"Melbourne Sexual Health Centre Alfred Health  Melbourne Australia"},{"name":"Melbourne School of Population Health University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,4,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.01.015"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70080-3"},{"key":"e_1_2_6_4_1","first-page":"43","volume-title":"SEER Survival Monograph: Cancer Survival Among Adults: U.S. SEER Program, 1988\u20132001, Patient and Tumor Characteristics","author":"Madeleine MMNL","year":"2007"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2004.09.060"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-007-9154-7"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0956462413486776"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181a65f5f"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3281c61201"},{"key":"e_1_2_6_10_1","volume-title":"Neoplastic Complications of HIV Infection","author":"Guideline","year":"2007"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jana.2011.08.006"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0b013e32831a6fe0"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1071\/SH10152"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1086\/605292"},{"key":"e_1_2_6_15_1","first-page":"1","article-title":"Pau A and Masur H. 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