{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:14:13Z","timestamp":1790874853831,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,9,17]],"date-time":"2014-09-17T00:00:00Z","timestamp":1410912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01 HL090342"],"award-info":[{"award-number":["R01 HL090342"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["U10 AA13566"],"award-info":[{"award-number":["U10 AA13566"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["U24 AA020794"],"award-info":[{"award-number":["U24 AA020794"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["U01 AA020790"],"award-info":[{"award-number":["U01 AA020790"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","award":["V1CDA2012-20"],"award-info":[{"award-number":["V1CDA2012-20"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2015,2]]},"abstract":"Objectives<\/jats:title>In HIV<\/jats:styled-content>\u2010uninfected populations, obstructive sleep apnoea (OSA<\/jats:styled-content>) is commonly associated with cardiovascular disease, metabolic syndrome, and cognitive impairment. These comorbidities are common in HIV<\/jats:styled-content>\u2010infected patients, but there are scarce data regarding OSA<\/jats:styled-content> in HIV<\/jats:styled-content>\u2010infected patients. Therefore, we examined the prevalence and correlates of OSA<\/jats:styled-content> in a cohort of HIV<\/jats:styled-content>\u2010infected and uninfected patients.<\/jats:p><\/jats:sec>Methods<\/jats:title>An observational cohort study was carried out. Electronic medical record and self\u2010report data were examined in patients enrolled in the Veterans Aging Cohort Study (VACS<\/jats:styled-content>) between 2002 and 2008 and followed until 2010. The primary outcome was OSA<\/jats:styled-content> diagnosis, determined using International Classification of Diseases, 9th edition (ICD<\/jats:styled-content>\u20109) codes, in HIV<\/jats:styled-content>\u2010infected compared with uninfected individuals. We used regression analyses to determine the association between OSA<\/jats:styled-content> diagnosis, symptoms and comorbidities in adjusted models.<\/jats:p><\/jats:sec>Results<\/jats:title>Of 3683 HIV<\/jats:styled-content>\u2010infected and 3641 uninfected patients, 143 (3.9%) and 453 (12.4%) had a diagnosis of OSA<\/jats:styled-content> (p\u2009<\u20090.0001), respectively. HIV<\/jats:styled-content>\u2010infected patients were more likely to report symptoms associated with OSA<\/jats:styled-content> such as tiredness and fatigue. Compared with uninfected patients with OSA<\/jats:styled-content>, HIV<\/jats:styled-content>\u2010infected patients with OSA<\/jats:styled-content> were younger, had lower body mass indexes (BMIs<\/jats:styled-content>), and were less likely to have hypertension. In models adjusting for these traditional OSA<\/jats:styled-content> risk factors, HIV<\/jats:styled-content> infection was associated with markedly reduced odds of OSA<\/jats:styled-content> diagnosis (odds ratio 0.48; 95% confidence interval 0.39\u20100.60).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>HIV<\/jats:styled-content>\u2010infected patients are less likely to receive a diagnosis of OSA<\/jats:styled-content>. Future studies are needed to determine whether the lower prevalence of OSA<\/jats:styled-content> diagnoses in HIV<\/jats:styled-content>\u2010infected patients is attributable to decreased screening and detection or to a truly decreased likelihood of OSA<\/jats:styled-content> in the setting of HIV<\/jats:styled-content> infection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.12182","type":"journal-article","created":{"date-parts":[[2014,9,18]],"date-time":"2014-09-18T03:38:57Z","timestamp":1411011537000},"page":"105-113","source":"Crossref","is-referenced-by-count":30,"title":["Prevalence and correlates of obstructive sleep apnoea among patients with and without HIV<\/scp> infection"],"prefix":"10.1111","volume":"16","author":[{"given":"KM","family":"Kunisaki","sequence":"first","affiliation":[{"name":"Minneapolis VA Health Care System Minneapolis MN USA"},{"name":"University of Minnesota Minneapolis MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KM","family":"Akg\u00fcn","sequence":"additional","affiliation":[{"name":"VA Connecticut Health Care System West Haven CT USA"},{"name":"Yale School of Medicine New Haven CT USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DA","family":"Fiellin","sequence":"additional","affiliation":[{"name":"Yale School of Medicine New Haven CT USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CL","family":"Gibert","sequence":"additional","affiliation":[{"name":"Washington D.C. VA Medical Center Washington, DC USA"},{"name":"George Washington University Washington, DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JW","family":"Kim","sequence":"additional","affiliation":[{"name":"James J. Peters VA Medical Center Bronx NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Rimland","sequence":"additional","affiliation":[{"name":"Atlanta VA Medical Center Atlanta GA USA"},{"name":"Emory University Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MC","family":"Rodriguez\u2010Barradas","sequence":"additional","affiliation":[{"name":"Michael E. DeBakey VA Medical Center Houston TX USA"},{"name":"Baylor College of Medicine Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HK","family":"Yaggi","sequence":"additional","affiliation":[{"name":"VA Connecticut Health Care System West Haven CT USA"},{"name":"Yale School of Medicine New Haven CT USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Crothers","sequence":"additional","affiliation":[{"name":"University of Washington Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1997.00440360178019"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200005113421901"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.14.1829"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)71141-7"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043104"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2009.138"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.4.447"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.1115"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200312-1782OC"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199903183401104"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.162.8.893"},{"issue":"3","key":"e_1_2_7_13_1","article-title":"Diagnosis of HIV infection among adults aged 50 years and older in the United States and dependent areas, 2007\u20132010","volume":"18","author":"Centers for Disease Control and Prevention (CDC)","year":"2013","journal-title":"HIV Surveill Suppl Rep"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e31827303d5"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1086\/523577"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2013.3728"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000223741.02074.66"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000228003.08925.8c"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27032"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200605000-00026"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31816d83e4"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.3851\/IMP1572"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000223670.00890.74"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201006-0836OC"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2011.151"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32832bd7af"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.3851\/IMP2745"}],"container-title":["HIV Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhiv.12182","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hiv.12182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T12:30:55Z","timestamp":1696249855000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hiv.12182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,17]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["10.1111\/hiv.12182"],"URL":"https:\/\/doi.org\/10.1111\/hiv.12182","archive":["Portico"],"relation":{},"ISSN":["1464-2662","1468-1293"],"issn-type":[{"value":"1464-2662","type":"print"},{"value":"1468-1293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,17]]}}}