{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T17:18:37Z","timestamp":1763140717495},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,9,17]],"date-time":"2014-09-17T00:00:00Z","timestamp":1410912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Men diagnosed with rectal gonorrhoea (<jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content>) and chlamydia (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) have engaged in unprotected receptive anal intercourse. We reviewed the <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> positivity and <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> viral loads (<jats:styled-content style=\"fixed-case\">VLs<\/jats:styled-content>) of men who had rectal <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> testing to evaluate potential <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> acquisition and transmission risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Rectal <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> testing data for men attending the <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>aricopa <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ounty <jats:styled-content style=\"fixed-case\">STD<\/jats:styled-content> clinic during the period from 1 <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ctober 2011 to 30 <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>eptember 2013 were cross\u2010matched with <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> surveillance data to identify men with <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> coinfection. We examined <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> status, <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> diagnosis date, and the values of <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content> collected nearest to the date of reported rectal infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the 2\u2010year time period, 1591 men were tested for rectal <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>. Of the men tested, 506 (31.8%) were positive for <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content> (13.2%), <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> (12.2%) or both (6.4%); 119 (23.5%) of those with rectal <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> were coinfected with <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>. Among the 275 men with <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> at the time of rectal testing, 54 (19.6%) had no reported <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content>; 63 (22.9%) had an undetectable <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content> (&lt;\u200920 <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u20101 <jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content> copies\/mL) and 158 (57.4%) had a detectable <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content> collected within 1 year of rectal diagnosis. Mean <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content> was higher among <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> and rectal <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> coinfected cases compared with men with <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> alone (174\u2009316 <jats:italic>vs.<\/jats:italic> 57\u2009717\u2009copies\/mL, respectively; <jats:italic>P<\/jats:italic>\u2009=\u20090.04).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Approximately one\u2010third of men undergoing rectal testing were positive for <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> and one\u2010quarter of men with rectal <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> also had <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> infection. Of the <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected men tested for rectal <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>, more than half had a detectable <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content> collected near the time of rectal testing, demonstrating a risk for transmitting <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.12192","type":"journal-article","created":{"date-parts":[[2014,9,18]],"date-time":"2014-09-18T03:39:30Z","timestamp":1411011570000},"page":"249-254","source":"Crossref","is-referenced-by-count":15,"title":["<scp>HIV<\/scp> status and viral loads among men testing positive for rectal gonorrhoea and chlamydia, <scp>M<\/scp>aricopa <scp>C<\/scp>ounty, <scp>A<\/scp>rizona, <scp>USA<\/scp>, 2011\u20132013"],"prefix":"10.1111","volume":"16","author":[{"given":"MM","family":"Taylor","sequence":"first","affiliation":[{"name":"Division of STD Prevention Centers for Disease Control and Prevention  Atlanta GA USA"},{"name":"Maricopa County Department of Public Health  Phoenix AZ USA"},{"name":"STD Program Arizona Department of Health Services  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DR","family":"Newman","sequence":"additional","affiliation":[{"name":"Division of STD Prevention Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"HIV Surveillance Program Arizona Department of Health Services  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Skinner","sequence":"additional","affiliation":[{"name":"HIV Surveillance Program Arizona Department of Health Services  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Khurana","sequence":"additional","affiliation":[{"name":"Maricopa County Department of Public Health  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Mickey","sequence":"additional","affiliation":[{"name":"Maricopa County Department of Public Health  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e3181c3ef29"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e318195bd2b"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e3181b48f33"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit437"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e31828fd163"},{"key":"e_1_2_6_7_1","first-page":"716","article-title":"Clinic\u2010based testing for rectal and pharyngeal Neisseria gonorrhoeae and Chlamydia trachomatis infection by community\u2010based organizations \u2013 five cities, United States, 2007","volume":"58","author":"Centers for Disease Control and Prevention","year":"2009","journal-title":"Morb Mortal Wkly Rep"},{"issue":"1","key":"e_1_2_6_8_1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1177\/00333549141291S113","article-title":"Trends in reported syphilis and gonorrhea among persons infected with HIV in Arizona: implications for prevention and control","volume":"129","author":"Skinner JM","year":"2014","journal-title":"Public Health Rep"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e318299cf00"},{"key":"e_1_2_6_10_1","unstructured":"SuJR WeinstockHS.Epidemiology of co\u2010infection with HIV and syphilis in 34 states United States 2009.National HIV Prevention Conference. 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