{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T10:06:59Z","timestamp":1768644419822,"version":"3.49.0"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,2,27]],"date-time":"2015-02-27T00:00:00Z","timestamp":1424995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003323","name":"Agence Nationale de Recherches sur le Sida et les Hepatites Virales","doi-asserted-by":"publisher","award":["ANRS 12110"],"award-info":[{"award-number":["ANRS 12110"]}],"id":[{"id":"10.13039\/501100003323","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ensemble pour une Solidarit\u00c3\u00a9 Th\u00c3\u00a9rapeutique Hospitali\u00c3\u00a8re En R\u00c3\u00a9seau (ESTHER)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2015,5]]},"abstract":"Objectives<\/jats:title>The World Health Organization (WHO<\/jats:styled-content>) recommends task\u2010shifting HIV<\/jats:styled-content> care to nurses in low\u2010resource settings with limited numbers of physicians. However, the effect of such task\u2010shifting on the health\u2010related quality of life (HRQL<\/jats:styled-content>) of people living with HIV<\/jats:styled-content> (PLHIV<\/jats:styled-content>) has seldom been evaluated. We aimed to investigate the effect of task\u2010shifting HIV<\/jats:styled-content> care to nurses on HRQL<\/jats:styled-content> outcomes in PLHIV<\/jats:styled-content> initiating antiretroviral therapy (ART<\/jats:styled-content>) in rural district hospitals in C<\/jats:styled-content>ameroon.<\/jats:p><\/jats:sec>Methods<\/jats:title>Outcomes in PLHIV<\/jats:styled-content> were longitudinally collected in the 2006\u22122010 Stratall trial. PLHIV<\/jats:styled-content> were followed up for 24 months by nurses and\/or physicians. Six HRQL<\/jats:styled-content> dimensions were assessed during face\u2010to\u2010face interviews using the WHO<\/jats:styled-content> Quality of Life (WHOQOL<\/jats:styled-content>)\u2010HIV BREF<\/jats:styled-content> scale: physical health; psychological health; independence level; social relationships; environment; and spirituality\/religion\/personal beliefs. The degree of task\u2010shifting was estimated using a consultant ratio (i.e. the ratio of nurse\u2010led to physician\u2010led visits). The effect of task\u2010shifting and other potential correlates on HRQL<\/jats:styled-content> dimensions was explored using a Heckman two\u2010stage approach based on linear mixed models to adjust for the potential bias caused by missing data in the outcomes.<\/jats:p><\/jats:sec>Results<\/jats:title>Of 1424 visits in 440 PLHIV<\/jats:styled-content> (70.5% female; median age 36 years; median CD4<\/jats:styled-content> count 188 cells\/\u03bcL at enrolment), 423 (29.7%) were task\u2010shifted to nurses. After multiple adjustment, task\u2010shifting was associated with higher HRQL<\/jats:styled-content> level for four dimensions: physical health [coefficient 0.7; 95% confidence interval (CI<\/jats:styled-content>) 0.1\u20131.2; P<\/jats:italic>\u2009=\u20090.01], psychological health (coefficient 0.5; 95% CI<\/jats:styled-content> 0.0\u20131.0; P<\/jats:italic>\u2009=\u20090.05), independence level (coefficient 0.6; 95% CI<\/jats:styled-content> 0.1\u20131.1; P<\/jats:italic>\u2009=\u20090.01) and environment (coefficient 0.6; 95% CI<\/jats:styled-content> 0.1\u20131.0; P<\/jats:italic>\u2009=\u20090.02).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Task\u2010shifting HIV<\/jats:styled-content> care to nurses benefits the HRQL<\/jats:styled-content> of PLHIV<\/jats:styled-content>. Together with the previously demonstrated comparable clinical effectiveness of physician\u2010based and nurse\u2010based models of HIV<\/jats:styled-content> care, our results support the WHO<\/jats:styled-content> recommendation for task\u2010shifting.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.12213","type":"journal-article","created":{"date-parts":[[2015,2,27]],"date-time":"2015-02-27T06:34:08Z","timestamp":1425018848000},"page":"307-318","source":"Crossref","is-referenced-by-count":16,"title":["Benefits of task\u2010shifting HIV<\/scp> care to nurses in terms of health\u2010related quality of life in patients initiating antiretroviral therapy in rural district hospitals in C<\/scp>ameroon [Stratall Agence Nationale de Recherche sur le SIDA<\/scp> (ANRS<\/scp>) 12110\/Ensemble pour une Solidarit\u00e9 Th\u00e9rapeutique Hospitali\u00e8re en R\u00e9seau (ESTHER<\/scp>) substudy]"],"prefix":"10.1111","volume":"16","author":[{"given":"M","family":"Suzan\u2010Monti","sequence":"first","affiliation":[{"name":"INSERM UMR912 Economics and Social Sciences Applied to Health & Analysis of Medical Information (SESSTIM) 13006 Marseille France"},{"name":"Aix Marseille University UMR_S912 IRD 13006 Marseille France"},{"name":"ORS PACA Southeastern Health Regional Observatory 13006 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Blanche","sequence":"additional","affiliation":[{"name":"INSERM UMR912 Economics and Social Sciences Applied to Health & Analysis of Medical Information (SESSTIM) 13006 Marseille France"},{"name":"Aix Marseille University UMR_S912 IRD 13006 Marseille France"},{"name":"ORS PACA Southeastern Health Regional Observatory 13006 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Boyer","sequence":"additional","affiliation":[{"name":"INSERM UMR912 Economics and Social Sciences Applied to Health & Analysis of Medical Information (SESSTIM) 13006 Marseille France"},{"name":"Aix Marseille University UMR_S912 IRD 13006 Marseille France"},{"name":"ORS PACA Southeastern Health Regional Observatory 13006 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Kouanfack","sequence":"additional","affiliation":[{"name":"Central Hospital UMI 233 Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Delaporte","sequence":"additional","affiliation":[{"name":"Socio\u2010anthropological Research Institute (IRSA) Catholic University of Central African States Yaound\u00e9 Cameroon"},{"name":"Institut de Recherche pour le D\u00e9veloppement (IRD) University Montpellier 1 UMI 233 Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u2010C","family":"Bonono","sequence":"additional","affiliation":[{"name":"Socio\u2010anthropological Research Institute (IRSA) Catholic University of Central African States Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PM","family":"Carrieri","sequence":"additional","affiliation":[{"name":"INSERM UMR912 Economics and Social Sciences Applied to Health & Analysis of Medical Information (SESSTIM) 13006 Marseille France"},{"name":"Aix Marseille University UMR_S912 IRD 13006 Marseille France"},{"name":"ORS PACA Southeastern Health Regional Observatory 13006 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Protopopescu","sequence":"additional","affiliation":[{"name":"INSERM UMR912 Economics and Social Sciences Applied to Health & Analysis of Medical Information (SESSTIM) 13006 Marseille France"},{"name":"Aix Marseille University UMR_S912 IRD 13006 Marseille France"},{"name":"ORS PACA Southeastern Health Regional Observatory 13006 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Laurent","sequence":"additional","affiliation":[{"name":"Institut de Recherche pour le D\u00e9veloppement (IRD) University Montpellier 1 UMI 233 Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Spire","sequence":"additional","affiliation":[{"name":"INSERM UMR912 Economics and Social Sciences Applied to Health & Analysis of Medical Information (SESSTIM) 13006 Marseille France"},{"name":"Aix Marseille University UMR_S912 IRD 13006 Marseille France"},{"name":"ORS PACA Southeastern Health Regional Observatory 13006 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Stratall ANRS 12110\/ESTHER Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.7448\/IAS.16.1.18757"},{"key":"e_1_2_7_3_1","unstructured":"WHO.Task shifting?: rational redistribution of tasks among health workforce teams?: global recommendations and guidelines.2008. Available athttp:\/\/www.who.int\/healthsystems\/TTR\u2010TaskShifting.pdf?ua=1(accessed August 2014)."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsb071889"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1057\/jphp.2011.8"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0b013e328333b87a"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1478-4491-8-8"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/heapol\/czs058"},{"key":"e_1_2_7_9_1","unstructured":"UNAIDS.Global report 2013. UNAIDS report on the global AIDS epidemic2013. Available athttp:\/\/www.unaids.org\/en\/resources\/campaigns\/globalreport2013\/globalreport\/(accessed August 2014)."},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1057\/jphp.2011.4"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540120902884034"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000366078.45451.46"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540120412331319714"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-7-244"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540120701203915"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540120802241863"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-007-9260-y"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000366079.83568.a2"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1758-2652-12-5"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-9-103"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/heapol\/czr039"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11205-006-9011-4"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-8-210"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e318285f7b6"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(11)70168-2"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540120412331290194"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-010-9863-0"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0073180"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.psy.0000188434.52941.a0"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/hec.1471"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6773.2011.01312.x"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/014662167700100306"},{"key":"e_1_2_7_33_1","first-page":"475","article-title":"The common structure of statistical models of truncation, sample selection and limited dependent variables and a simple estimator for such models","volume":"5","author":"Heckman J","year":"1976","journal-title":"Ann Econ Soc Meas"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1469"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119013563"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780070131"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000186364.27587.0e"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055225"},{"key":"e_1_2_7_39_1","unstructured":"Ministry of Public Health.National Strategic Plan on HIV\/AIDS 2006\u20102010 of the health sector progress report (draft)[in French].2010."},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540120410001716441"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1497.2006.00399.x"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0042980"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540120902889926"},{"key":"e_1_2_7_44_1","unstructured":"World Health Organization.WHO | consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection.2013. Available athttp:\/\/www.who.int\/hiv\/pub\/guidelines\/arv2013\/en\/(accessed August 2014)."},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkp232"}],"container-title":["HIV Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhiv.12213","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hiv.12213","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T07:28:06Z","timestamp":1729582086000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hiv.12213"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,27]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["10.1111\/hiv.12213"],"URL":"https:\/\/doi.org\/10.1111\/hiv.12213","archive":["Portico"],"relation":{},"ISSN":["1464-2662","1468-1293"],"issn-type":[{"value":"1464-2662","type":"print"},{"value":"1468-1293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,27]]}}}