{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:23:12Z","timestamp":1761578592900},"reference-count":64,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,2,17]],"date-time":"2015-02-17T00:00:00Z","timestamp":1424131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Women of reproductive age represent a large proportion of the global population living with <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AIDS<\/jats:styled-content>. With improvements in morbidity and mortality since the advent of combination antiretroviral therapy, contraception and pregnancy planning are an increasingly important issue for women living with <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>. This review aims to outline the key considerations when choosing contraceptive methods in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive women and provides a review of the literature to inform decision\u2010making.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Pubmed was searched using the terms \u2018<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2019, \u2018contraception\u2019, \u2018<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> progression\u2019, \u2018<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> acquisition\u2019, \u2018<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> transmission\u2019 and the combination of \u2018antiretroviral\u2019 and \u2018contraception\u2019. Abstracts were reviewed and relevant articles were retrieved. Reference lists were also reviewed for pertinent citations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> and contraceptive methods can interact in several clinically meaningful ways. Concomitant use may result in altered contraceptive efficacy, drug\u2212drug interactions, or increased toxicity. Hormonal contraceptives have not been shown to affect <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> progression. Notably, the impact of hormonal contraceptives on <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> transmission and acquisition remains unclear, particularly for injectable forms. Data are lacking on several newer methods of contraception including contraceptive rings, patches and intrauterine systems.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Effective, reliable contraception is important for <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive women. Efficacy, toxicity, drug interactions, and potential impacts on <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> disease progression, transmission, and acquisition must be assessed when making clinical decisions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.12221","type":"journal-article","created":{"date-parts":[[2015,2,17]],"date-time":"2015-02-17T11:11:42Z","timestamp":1424171502000},"page":"329-336","source":"Crossref","is-referenced-by-count":8,"title":["Contraceptive options for <scp>HIV<\/scp>\u2010positive women: making evidence\u2010based, patient\u2010centred decisions"],"prefix":"10.1111","volume":"16","author":[{"given":"M","family":"Sharma","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SL","family":"Walmsley","sequence":"additional","affiliation":[{"name":"Division of Experimental Therapeutics \u2013 Infection and Immunity Toronto General Research Institute  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,17]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"UNAIDS.Global Report: UNAIDS Report on the Global AIDS pandemic 2010.2010. 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