{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T17:56:07Z","timestamp":1773424567589,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,5,11]],"date-time":"2015-05-11T00:00:00Z","timestamp":1431302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2015,10]]},"abstract":"Objectives<\/jats:title>While idiopathic pulmonary arterial hypertension (PAH<\/jats:styled-content>) is a rare disease, it is seen more frequently in patients with HIV<\/jats:styled-content> infection. The aim of this study was to evaluate the prevalence of pulmonary hypertension (PH<\/jats:styled-content>) in patients with HIV<\/jats:styled-content> infection by echocardiographic screening.<\/jats:p><\/jats:sec>Methods<\/jats:title>Echocardiography and N<\/jats:styled-content>\u2010terminal of the prohormone brain natriuretic peptide measurement were used to examine the prevalence of PH<\/jats:styled-content> prospectively in HIV<\/jats:styled-content>\u2010positive patients (n<\/jats:italic>\u2009=\u2009374) during routine follow\u2010up visits for HIV<\/jats:styled-content> disease.<\/jats:p><\/jats:sec>Results<\/jats:title>In echocardiographic screening, PH<\/jats:styled-content> was detected in a total of 23 of 374 HIV<\/jats:styled-content>\u2010infected patients (6.1%). Of these, three patients (13%) presented with symptoms of dyspnoea and fatigue, and diagnosis of PAH<\/jats:styled-content> was confirmed by right heart catheterization. Patients with systolic pulmonary artery pressure (sPAP<\/jats:styled-content>)\u2009>\u200930\u2009mmHg were more likely to be female, to have a history of injecting drug use and to originate from high\u2010prevalence countries (HPCs<\/jats:styled-content>).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Echocardiographic screening detected PH<\/jats:styled-content> in a substantial proportion of HIV<\/jats:styled-content>\u2010positive patients. Female gender, a history of injecting drug use and HPC<\/jats:styled-content> origin were associated with a higher prevalence of HIV<\/jats:styled-content>\u2010associated PH<\/jats:styled-content>. The relevance and long\u2010term outcome of these findings need to be validated in follow\u2010up studies, which are ongoing.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.12261","type":"journal-article","created":{"date-parts":[[2015,5,11]],"date-time":"2015-05-11T07:57:37Z","timestamp":1431331057000},"page":"578-582","source":"Crossref","is-referenced-by-count":26,"title":["Pulmonary hypertension in HIV<\/scp> infection: a prospective echocardiographic study"],"prefix":"10.1111","volume":"16","author":[{"given":"C","family":"Schwarze\u2010Zander","sequence":"first","affiliation":[{"name":"Department of Internal Medicine I University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Pabst","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Hammerstingl","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Ohlig","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JC","family":"Wasmuth","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Boesecke","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Stoffel\u2010Wagner","sequence":"additional","affiliation":[{"name":"Institute for Clinical Chemistry and Clinical Pharmacology University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Carstensen","sequence":"additional","affiliation":[{"name":"Institute for Clinical Chemistry and Clinical Pharmacology University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Nickenig","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CP","family":"Strassburg","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JK","family":"Rockstroh","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Skowasch","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Schueler","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II University Hospital, University of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,5,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1586\/ers.11.10"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-013-0535-7"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.100.5.1268"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(87)80417-3"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00139009"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.10.029"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.118.4.1133"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.10.032"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2008.00602.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-014-0610-8"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.6.2722"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200704-541OC"},{"key":"e_1_2_6_14_1","unstructured":"Epidemiologisches Bulletin 4\/2013. 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