{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:51:29Z","timestamp":1787014289285,"version":"build-2736575974"},"reference-count":53,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,10,6]],"date-time":"2016-10-06T00:00:00Z","timestamp":1475712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U01\u2010AI\u201035042"],"award-info":[{"award-number":["U01\u2010AI\u201035042"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01\u2010HD\u2010032632"],"award-info":[{"award-number":["U01\u2010HD\u2010032632"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23\u2010AG\u2010050260"],"award-info":[{"award-number":["K23\u2010AG\u2010050260"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      Falls and fall\u2010related injuries are a major public health concern.\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      \u2010infected adults have been shown to have a high incidence of falls. Identification of major risk factors for falls that are unique to\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      infection or similar to those in the general population will inform development of future interventions for fall prevention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      \u2010infected and uninfected men and women participating in the Hearing and Balance Substudy of the Multicenter\n                      <jats:styled-content style=\"fixed-case\">AIDS<\/jats:styled-content>\n                      Cohort Study and Women's Interagency\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      Study were asked about balance symptoms and falls during the prior 12 months. Falls were categorized as 0, 1, or \u2265 2; proportional odds logistic regression models were used to investigate relationships between falls and demographic and clinical variables and multivariable models were created.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010four per cent of 303\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      \u2010infected participants reported at least one fall compared with 18% of 233\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      \u2010uninfected participants (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.27).\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      \u2010infected participants were demographically different from\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      \u2010uninfected participants, and were more likely to report clinical imbalance symptoms (\n                      <jats:italic>P<\/jats:italic>\n                      \u2264 0.035). In univariate analyses, more falls were associated with hepatitis C, female sex, obesity, smoking, and clinical imbalance symptoms, but not age,\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      serostatus or other comorbidities. In multivariable analyses, female sex and imbalance symptoms were independently associated with more falls. Among\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      \u2010infected participants, smoking, a higher number of medications, and imbalance symptoms remained independent fall predictors, while current protease inhibitor use was protective.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Similar rates of falls among\n                      <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\n                      \u2010infected and uninfected participants were largely explained by a high prevalence of imbalance symptoms. Routine assessment of falls and dizziness\/imbalance symptoms should be considered, with interventions targeted at reducing symptomatology.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hiv.12378","type":"journal-article","created":{"date-parts":[[2016,3,31]],"date-time":"2016-03-31T16:25:11Z","timestamp":1459441511000},"page":"740-748","source":"Crossref","is-referenced-by-count":56,"title":["Fall frequency and associated factors among men and women with or at risk for\n                    <scp>HIV<\/scp>\n                    infection"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0808-6729","authenticated-orcid":false,"given":"KM","family":"Erlandson","sequence":"first","affiliation":[{"name":"Department of Medicine Divisions of Infectious Diseases and Geriatric Medicine University of Colorado Aurora CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MW","family":"Plankey","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Infectious Diseases Georgetown University Medical Center Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Springer","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Bloomberg School of Public Health Johns Hopkins University Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HS","family":"Cohen","sequence":"additional","affiliation":[{"name":"Bobby R. Alford Department of Otolaryngology\u2013Head and Neck Surgery Baylor College of Medicine Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Cox","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Bloomberg School of Public Health Johns Hopkins University Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HJ","family":"Hoffman","sequence":"additional","affiliation":[{"name":"Epidemiology and Statistics Program National Institute on Deafness and Other Communication Disorders (NIDCD) National Institutes of Health (NIH) Bethesda MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MT","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Infectious Diseases Columbia University Medical Center New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TT","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Endocrinology, Diabetes &amp; Metabolism Johns Hopkins University Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,10,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(01)00349-3"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-200101000-00021"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/53A.2.M112"},{"key":"e_1_2_6_5_1","first-page":"153","article-title":"Environmental determinants of physical activity and sedentary behavior","volume":"28","author":"Owen N","year":"2000","journal-title":"Exerc Sport Sci Rev"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e3182716e38"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.84.4.565"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/26.3.189"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/46.5.M164"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3851\/IMP2979"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(13)70181-5"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1310\/hct1306-324"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000000674"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3280148c05"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328361d241"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/126.2.310"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199803000-00004"},{"key":"e_1_2_6_18_1","unstructured":"Panel on Antiretroviral Guidelines for Adults and Adolescents.Guidelines for the Use of Antiretroviral Agents in HIV\u20101\u2010Infected Adults and Adolescents. Department of Health and Human Services. Available athttp:\/\/aidsinfo.nih.gov\/guidelines(accessed 15 December 2014)."},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0038419"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0b013e3182a021c8"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2012.07.005"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2013.3913"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.88.2.174"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-130-6-199903160-00002"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/13803395.2010.547662"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.3109\/13550284.2010.504249"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2011.11.009"},{"key":"e_1_2_6_28_1","unstructured":"HealthR.Medical Outcomes Study: 36\u2010item short form survey instrument. Rand 36\u2010item Health Survey 1.0 Questionnaire Items. Available athttp:\/\/www.rand.org\/health\/surveys_tools\/mos\/mos_core_36item_survey.html(accessed 04 June 2015)."},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.7224\/1537-2073.2014-076"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0123390"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.2024"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24806"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-009-0909-y"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2014.09.034"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/00126334-200306012-00005"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1086\/423181"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000000606"},{"key":"e_1_2_6_38_1","unstructured":"Highlights of prescribing information: Atripla (efavirenz\/emtricitabine\/tenofovir disoproxil fumarate) tablet for oral use. Initial U.S. Approval: 2006. Available athttp:\/\/packageinserts.bms.com\/pi\/pi_atripla.pdf(accessed 25 June 2015)."},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32835584ea"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.3109\/14992027.2012.721935"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215107001624"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3283455dff"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-010-9107-y"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2007.00385.x"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20100292"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13365-013-0160-3"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13365-013-0198-2"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2006.00297.x"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2318-8-6"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq024"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2318-14-105"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20090163"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199409293311301"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2015.3962"}],"container-title":["HIV Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhiv.12378","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hiv.12378","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T21:05:18Z","timestamp":1696280718000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hiv.12378"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,6]]},"references-count":53,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1111\/hiv.12378"],"URL":"https:\/\/doi.org\/10.1111\/hiv.12378","archive":["Portico"],"relation":{},"ISSN":["1464-2662","1468-1293"],"issn-type":[{"value":"1464-2662","type":"print"},{"value":"1468-1293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,6]]}}}