{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T15:45:05Z","timestamp":1773675905566,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,10,6]],"date-time":"2016-10-06T00:00:00Z","timestamp":1475712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective of this nested study was to assess the prevalence of psychiatric disorders in a sample of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\/hepatitis C virus (<jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content>)\u2010coinfected patients according to their <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The nested cross\u2010sectional study, untitled HEPAVIH\u2010Psy survey, was performed in a subset of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content>\u2010coinfected patients enrolled in the French Agence Nationale de Recherche sur le <jats:styled-content style=\"fixed-case\">SIDA<\/jats:styled-content> et les H\u00e9patites Virales (<jats:styled-content style=\"fixed-case\">ANRS<\/jats:styled-content>) <jats:styled-content style=\"fixed-case\">CO<\/jats:styled-content>13 <jats:styled-content style=\"fixed-case\">HEPAVIH<\/jats:styled-content> cohort. Psychiatric disorders were screened for using the Mini International Neuropsychiatric Interview (<jats:styled-content style=\"fixed-case\">MINI<\/jats:styled-content> 5.0.0).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 286 patients enrolled in the study, 68 (24%) had never received <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> treatment, 87 (30%) were treatment nonresponders, 44 (15%) were currently being treated and 87 (30%) had a sustained virological response (<jats:styled-content style=\"fixed-case\">SVR<\/jats:styled-content>). Of the 286 patients enrolled, 121 patients (42%) screened positive for a psychiatric disorder other than suicidality and alcohol\/drug abuse\/dependence, 40 (14%) screened positive for alcohol abuse\/dependence, 50 (18%) screened positive for drug abuse\/dependence, 50 (17.5%) were receiving an antidepressant treatment and 69 (24%) were receiving an anxiolytic. Patients with an <jats:styled-content style=\"fixed-case\">SVR<\/jats:styled-content> did not significantly differ from the other groups in terms of psychiatric disorders. Patients receiving <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> treatment screened positive less often for an anxiety disorder. The highest rate of drug dependence\/abuse was among <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> treatment\u2010na\u00efve patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Psychiatric disorders were frequent in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content>\u2010coinfected patients and their rates were comparable between groups, even for patients achieving an <jats:styled-content style=\"fixed-case\">SVR<\/jats:styled-content>. Our results emphasize the need for continuous assessment and care of coinfected patients, even after <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> clearance. Drug addiction remains an obstacle to access to <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> treatment. Despite the recent advent and continued development of directly acting antiviral agents (<jats:styled-content style=\"fixed-case\">DAA<\/jats:styled-content>s), it is still crucial to offer screening and comprehensive care for psychiatric and addictive disorders.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.12382","type":"journal-article","created":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T12:57:22Z","timestamp":1463489842000},"page":"758-765","source":"Crossref","is-referenced-by-count":5,"title":["Psychiatric and substance use disorders in <scp>HIV<\/scp>\/hepatitis C virus (<scp>HCV<\/scp>)\u2010coinfected patients: does <scp>HCV<\/scp> clearance matter? 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