{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T10:06:43Z","timestamp":1774519603434,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,1,27]],"date-time":"2017-01-27T00:00:00Z","timestamp":1485475200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of the study was to determine <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> incidence among men who have sex with men (<jats:styled-content style=\"fixed-case\">MSM<\/jats:styled-content>) who repeat test for <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> at sexually transmitted infection (<jats:styled-content style=\"fixed-case\">STI<\/jats:styled-content>) clinics in England, and identify associated factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Annual <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> incidence and 95% confidence interval (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) were calculated for a national cohort of <jats:styled-content style=\"fixed-case\">MSM<\/jats:styled-content> who tested <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> negative at any <jats:styled-content style=\"fixed-case\">STI<\/jats:styled-content> clinic in England in 2012 and had a follow\u2010up test within 1 year using routinely collected data. Cox regression analyses were performed to identify predictors of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> acquisition and population attributable risk for <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> infection was calculated for predictors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 2012, 85 500 <jats:styled-content style=\"fixed-case\">MSM<\/jats:styled-content> not known to be <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> positive attended any <jats:styled-content style=\"fixed-case\">STI<\/jats:styled-content> clinic in England, and 31% tested for <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> at least twice within 1 year at the same clinic. <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> incidence was 2.0 per 100 person\u2010years (<jats:styled-content style=\"fixed-case\">PY<\/jats:styled-content>; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.8\u20132.2) among repeat testers. Incidence was higher among <jats:styled-content style=\"fixed-case\">MSM<\/jats:styled-content> of black ethnicity (3.2 per 100 <jats:styled-content style=\"fixed-case\">PY<\/jats:styled-content>) and those with a bacterial <jats:styled-content style=\"fixed-case\">STI<\/jats:styled-content> diagnosis at the initial attendance (3.2 per 100 <jats:styled-content style=\"fixed-case\">PY<\/jats:styled-content>). <jats:styled-content style=\"fixed-case\">MSM<\/jats:styled-content> with a previous syphilis or gonorrhoea infection were at significantly greater risk of acquiring <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> in the subsequent year [adjusted hazard ratio 4.1 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 2.0\u20138.3) and 2.1 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.4\u20133.2), respectively]. The predictors accounted for 37% of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> infections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Annual <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> incidence among <jats:styled-content style=\"fixed-case\">MSM<\/jats:styled-content> attending <jats:styled-content style=\"fixed-case\">STI<\/jats:styled-content> clinics in England is high. Previous <jats:styled-content style=\"fixed-case\">STI<\/jats:styled-content>s were predictors of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> acquisition but only accounted for one in five infections. More discriminatory behavioural predictors of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> acquisition could provide better triaging of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> prevention services for <jats:styled-content style=\"fixed-case\">MSM<\/jats:styled-content> attending <jats:styled-content style=\"fixed-case\">STI<\/jats:styled-content> clinics.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.12498","type":"journal-article","created":{"date-parts":[[2017,1,27]],"date-time":"2017-01-27T06:29:24Z","timestamp":1485498564000},"page":"615-622","source":"Crossref","is-referenced-by-count":24,"title":["HIV incidence in an open national cohort of men who have sex with men attending sexually transmitted infection clinics in England"],"prefix":"10.1111","volume":"18","author":[{"given":"S","family":"Desai","sequence":"first","affiliation":[{"name":"HIV &amp; STI Department Centre for Infectious Disease Surveillance and Control Public Health England London UK"},{"name":"Research Department of Infection &amp; Population Health University College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Nardone","sequence":"additional","affiliation":[{"name":"HIV &amp; STI Department Centre for Infectious Disease Surveillance and Control Public Health England London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Hughes","sequence":"additional","affiliation":[{"name":"HIV &amp; STI Department Centre for Infectious Disease Surveillance and Control Public Health England London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Delpech","sequence":"additional","affiliation":[{"name":"HIV &amp; STI Department Centre for Infectious Disease Surveillance and Control Public Health England London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Burns","sequence":"additional","affiliation":[{"name":"Research Department of Infection &amp; Population Health University College London London UK"},{"name":"Royal Free London NHS Foundation Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Hart","sequence":"additional","affiliation":[{"name":"Research Department of Infection &amp; Population Health University College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ON","family":"Gill","sequence":"additional","affiliation":[{"name":"HIV &amp; STI Department Centre for Infectious Disease Surveillance and Control Public Health England London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,1,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES2015.20.14.21086"},{"key":"e_1_2_7_3_1","unstructured":"Public Health England.HIV: annual data tables. 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