{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T20:59:22Z","timestamp":1762376362959,"version":"3.37.3"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,3,24]],"date-time":"2018-03-24T00:00:00Z","timestamp":1521849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Measles infection is a vaccine\u2010preventable disease currently resurging in Europe. <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected subjects are at higher risk of complications following measles infection. We investigated the risk factors associated with being seronegative in a cohort of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected subjects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected subjects in our cohort who had a measles serological test performed between December 2005 and May 2017 were retrospectively identified. A measles immunoglobulin G (IgG) titre &gt; 275 <jats:styled-content style=\"fixed-case\">mIU<\/jats:styled-content>\/mL was considered protective. Risk factors were analysed using logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Measles serology was available in 273 of 3124 subjects in active follow\u2010up (8.7%). The prevalence of measles seronegativity was 21.6% (59 of 273). In the univariate analysis, being born after 1970 and <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> infection by vertical transmission were both associated with a higher risk of measles seronegativity, while a nadir <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>4 T\u2010cell count &lt; 200 cells\/<jats:italic>\u03bc<\/jats:italic>L was associated with a lower risk of measles seronegativity. In the multivariate analysis, only being born after 1970 [odds ratio (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>) 4.9; 95% confidence interval (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) 1.3\u201318.7] and vertical transmission (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 7.7; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 3.3\u201318.3) were significantly associated with seronegativity. Among the vertically infected subjects with measles\u2010mumps\u2010rubella (<jats:styled-content style=\"fixed-case\">MMR<\/jats:styled-content>) immunization documentation, the median number of doses of vaccine received before testing was 2 (range 1\u20133).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected subjects born after 1970 and vertically infected subjects should be screened for measles seropositivity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.12610","type":"journal-article","created":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T00:05:39Z","timestamp":1521936339000},"page":"426-429","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Prevalence and risk factors of measles seronegativity in a cohort of <scp>HIV<\/scp>\u2010positive subjects: a retrospective study"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7697-6849","authenticated-orcid":false,"given":"N","family":"Dauby","sequence":"first","affiliation":[{"name":"Infectious Diseases Department CHU Saint\u2010Pierre Universit\u00e9 Libre de Bruxelles Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Martin","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department CHU Saint\u2010Pierre Universit\u00e9 Libre de Bruxelles Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Hainaut","sequence":"additional","affiliation":[{"name":"Pediatrics Department CHU Saint\u2010Pierre Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Grammens","sequence":"additional","affiliation":[{"name":"Service of Epidemiology of Infectious Diseases Department of Public Health and Surveillance Scientific Institute of Public Health Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Van den Wijngaert","sequence":"additional","affiliation":[{"name":"Microbiology Department Laboratoire Hospitalier Universitaire de Bruxelles (LHUB\u2010ULB) Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Delforge","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department CHU Saint\u2010Pierre Universit\u00e9 Libre de Bruxelles Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"De Wit","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department CHU Saint\u2010Pierre Universit\u00e9 Libre de Bruxelles Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31463-0"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1903.121360"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2016.21.32.30313"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1086\/520136"},{"key":"e_1_2_5_6_1","unstructured":"LundgrenJ GatellJ RockstrohJ FurrerH.EACS Guidelines version 8.2. 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