{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T18:01:36Z","timestamp":1773079296885,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,8,19]],"date-time":"2019-08-19T00:00:00Z","timestamp":1566172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2019,11]]},"abstract":"Objectives<\/jats:title>In July 2016, as a result of patient demand, we introduced a rapid initiation option (RIO<\/jats:styled-content>) to offer a first medical appointment and antiretroviral therapy (ART<\/jats:styled-content>) initiation within 2\u00a0days of HIV<\/jats:styled-content> diagnosis at 56 Dean Street (56DS) , a combined sexual health and HIV<\/jats:styled-content> treatment service in London, UK<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>We performed a retrospective case\u2010note review of patients newly diagnosed with HIV<\/jats:styled-content> infection at 56DS<\/jats:styled-content> following the introduction of the new RIO<\/jats:styled-content> from July to October 2016. In order to assess the effect of the new service on ART<\/jats:styled-content> uptake, we chose a comparison group of newly diagnosed patients at 56DS<\/jats:styled-content> from 1\u00a0year earlier: July to October 2015.<\/jats:p><\/jats:sec>Results<\/jats:title>In the 4\u00a0months following RIO<\/jats:styled-content> introduction, there was a reduction in the median time from HIV<\/jats:styled-content> diagnosis to the first medical appointment (7 versus 15\u00a0days; P<\/jats:italic>\u00a0<\u00a00.00001) and to ART<\/jats:styled-content> initiation (8 versus 21\u00a0days; P<\/jats:italic>\u00a0<\u00a00.00001) compared with the same 4\u2010month period 1\u00a0year previously. Uptake of ART<\/jats:styled-content> at first appointment also significantly increased from 60% to 76% (P<\/jats:italic>\u00a0=\u00a00.0074).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>By increasing our clinic capacity and awareness of staff and patients of the RIO<\/jats:styled-content> service, we were able to fulfil the aim of the service to offer ART<\/jats:styled-content> more quickly following HIV<\/jats:styled-content> diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.12780","type":"journal-article","created":{"date-parts":[[2019,8,19]],"date-time":"2019-08-19T14:09:46Z","timestamp":1566223786000},"page":"699-703","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Rapid initiation of antiretroviral therapy in those with newly diagnosed HIV<\/scp> infection in London, UK<\/scp>"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3070-1281","authenticated-orcid":false,"given":"G","family":"Whitlock","sequence":"first","affiliation":[{"name":"56 Dean Street Chelsea and Westminster Hospital NHS Foundation Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Carbonell","sequence":"additional","affiliation":[{"name":"56 Dean Street Chelsea and Westminster Hospital NHS Foundation Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Blackwell","sequence":"additional","affiliation":[{"name":"56 Dean Street Chelsea and Westminster Hospital NHS Foundation Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Nwokolo","sequence":"additional","affiliation":[{"name":"56 Dean Street Chelsea and Westminster Hospital NHS Foundation Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the Dean Street Collaborative Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,19]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"British HIV Association guidelines for the treatment of HIV\u20101\u2010positive adults with antiretroviral therapy 2015(2016interim update). Available athttps:\/\/www.bhiva.org\/file\/RVYKzFwyxpgiI\/treatment-guidelines-2016-interim-update.pdf(accessed 1 January 2019)."},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005575"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(13)70692-3"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001134"},{"key":"e_1_2_5_6_1","unstructured":"Public Health England RITA website (September2013). Available athttps:\/\/webarchive.nationalarchives.gov.uk\/20140714095636\/http:\/\/www.hpa.org.uk\/webc\/HPAwebFile\/HPAweb_C\/1317139917891(accessed 1 January 2019)."},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(17)30044-9"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.3851\/IMP3080"},{"key":"e_1_2_5_9_1","unstructured":"Maughan\u2010BrownB SmithP KuoCet\u00a0al.Readiness for antiretroviral therapy: implications for linking HIV\u2010infected individuals to care and treatment.9th IAS Conference on HIV Science. Paris France July2017[Abstract MOAD0101].."},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e318281e772"},{"key":"e_1_2_5_11_1","unstructured":"WHO guidelines for rapid initiation of antiretroviral therapy(July2017). Available athttp:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/255884\/9789241550062-eng.pdf;jsessionxml:id=5F4591EE662BD3CAD653B50B3434C585?sequence=1(accessed 1 January 2019)."},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000601"}],"container-title":["HIV Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhiv.12780","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hiv.12780","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/hiv.12780","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hiv.12780","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T03:15:13Z","timestamp":1694142913000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hiv.12780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,19]]},"references-count":11,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1111\/hiv.12780"],"URL":"https:\/\/doi.org\/10.1111\/hiv.12780","archive":["Portico"],"relation":{},"ISSN":["1464-2662","1468-1293"],"issn-type":[{"value":"1464-2662","type":"print"},{"value":"1468-1293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,19]]},"assertion":[{"value":"2019-05-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}