{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T13:14:39Z","timestamp":1785503679162,"version":"3.56.0"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T00:00:00Z","timestamp":1601942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HL007287"],"award-info":[{"award-number":["HL007287"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HL090342"],"award-info":[{"award-number":["HL090342"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["HL126536"],"award-info":[{"award-number":["HL126536"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The relationship between marijuana use and markers of chronic lung disease in people living with HIV (PLWH) is poorly understood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a cross\u2010sectional analysis of the Examinations of HIV\u2010Associated Lung Emphysema (EXHALE) study, including 162 HIV\u2010positive patients and 138 participants without HIV. We modelled marijuana exposure as: (i) current daily or weekly marijuana smoking <jats:italic>vs<\/jats:italic>. monthly or less often; or (ii) cumulative marijuana smoking (joint\u2010years). Linear and logistic regression estimated associations between marijuana exposure and markers of lung disease, adjusted for tobacco smoking and other factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In PLWH, current daily or weekly marijuana use was associated with a larger forced vital capacity (FVC), larger total lung capacity and increased odds of radiographic emphysema compared with marijuana non\u2010smokers in adjusted models; these associations were not statistically significant in participants without HIV. Marijuana joint\u2010years were associated with higher forced expiratory volume in 1\u00a0s and FVC in PLWH but not with emphysema.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In PLWH, marijuana smoking was associated with higher lung volumes and potentially with radiographic emphysema. No consistently negative associations were observed between marijuana and measures of chronic lung health.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.12966","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T21:49:58Z","timestamp":1602020998000},"page":"92-101","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Associations of marijuana with markers of chronic lung disease in people living with HIV"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5142-5402","authenticated-orcid":false,"given":"DS","family":"Wenger","sequence":"first","affiliation":[{"name":"Division of Pulmonary Critical Care and Sleep Medicine University of Washington Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Triplette","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Critical Care and Sleep Medicine University of Washington Seattle WA USA"},{"name":"Clinical Research Division Fred Hutchinson Cancer Research Center Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Shahrir","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Critical Care and Sleep Medicine University of Washington Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KM","family":"Akgun","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Veterans Affairs (VA) Connecticut Healthcare System and Yale University School of Medicine New Haven CT USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Wongtrakool","sequence":"additional","affiliation":[{"name":"Atlanta VA Medical Center and Department of Medicine Emory University School of Medicine Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ST","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Medicine James J. 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