{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T18:03:14Z","timestamp":1777485794407,"version":"3.51.4"},"reference-count":11,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T00:00:00Z","timestamp":1621209600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Tuberculosis (TB) is the most common opportunistic infection and cause of mortality among people living with HIV, and it is possible that it may also influence the evolution of the HIV infection. We assessed the differences between HIV\u2010positive and \u2010negative people infected with TB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The present study is a cross\u2010sectional retrospective study by electronic record revision. We included patients admitted to a tertiary hospital with a diagnosis of TB between 2011 and 2016, comparing those with HIV coinfection with non\u2010HIV patients, according to demographic and clinical characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study included 591 patients, of whom 32% were HIV\u2010coinfected. HIV\u2010TB patients were younger, with a predominance of male gender. Considering TB risk factors, there was a higher prevalence of homelessness and intravenous drug use in the HIV group. In the non\u2010HIV group, direct contact with other patients with TB and immunosuppression were more prevalent. Relative to TB characteristics, the HIV\u2010coinfected group presents with a higher prevalence of disseminated disease and a higher occurrence of previous TB infection. Cancer was the most frequent cause of immunosuppression in the HIV group and the number testing positive for TB via microbiological culture was lower. Assessment of microbiological resistance and in\u2010hospital mortality showed similar numbers in both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There are few papers comparing clinical course of TB between HIV\u2010infected and non\u2010infected patients. Our study differs from others in the literature as we focused on a country with middling incidence of TB and further characterized the differences between HIV\u2010infected and non\u2010infected patients which can contribute to the management of these patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.13119","type":"journal-article","created":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T17:38:02Z","timestamp":1621273082000},"page":"775-779","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Tuberculosis infection in HIV <i>vs<\/i>. non\u2010HIV patients"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6492-7185","authenticated-orcid":false,"given":"I","family":"Rego de Figueiredo","sequence":"first","affiliation":[{"name":"Medicina 7.2 Hospital Curry Cabral Centro Hospitalar Universit\u00e1rio Lisboa Central (CHULC) Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Branco Ferr\u00e3o","sequence":"additional","affiliation":[{"name":"Medicina 2.3 Hospital de Santo Ant\u00f3nio dos Capuchos Centro Hospitalar Universit\u00e1rio Lisboa Central (CHULC) Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Dias","sequence":"additional","affiliation":[{"name":"Medicina 7.2 Hospital Curry Cabral Centro Hospitalar Universit\u00e1rio Lisboa Central (CHULC) Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Vieira Alves","sequence":"additional","affiliation":[{"name":"Medicina 7.2 Hospital Curry Cabral Centro Hospitalar Universit\u00e1rio Lisboa Central (CHULC) Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Drummond Borges","sequence":"additional","affiliation":[{"name":"Medicina 7.2 Hospital Curry Cabral Centro Hospitalar Universit\u00e1rio Lisboa Central (CHULC) Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Torres","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Doen\u00e7as Infecciosas Hospital Curry Cabral Centro Hospitalar Universit\u00e1rio Lisboa Central (CHULC) Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Guerreiro Castro","sequence":"additional","affiliation":[{"name":"Medicina 7.2 Hospital Curry Cabral Centro Hospitalar Universit\u00e1rio Lisboa Central (CHULC) Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Louren\u00e7o","sequence":"additional","affiliation":[{"name":"Medicina 7.2 Hospital Curry Cabral Centro Hospitalar Universit\u00e1rio Lisboa Central (CHULC) Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AM","family":"Antunes","sequence":"additional","affiliation":[{"name":"Medicina 7.2 Hospital Curry Cabral Centro Hospitalar Universit\u00e1rio Lisboa Central (CHULC) Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Gruner","sequence":"additional","affiliation":[{"name":"Medicina 7.2 Hospital Curry Cabral Centro Hospitalar Universit\u00e1rio Lisboa Central (CHULC) Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Panarra","sequence":"additional","affiliation":[{"name":"Medicina 7.2 Hospital Curry Cabral Centro Hospitalar Universit\u00e1rio Lisboa Central (CHULC) Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,17]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"WHO.Global tuberculosis report 2020. WHO [Internet]. Available athttp:\/\/www.who.int\/tb\/publications\/global_report\/en\/(accessed 21 October 2020);2020."},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00042-10"},{"key":"e_1_2_7_4_1","unstructured":"[Internet]. Available athttps:\/\/www.pnvihsida.dgs.pt\/estudos\u2010e\u2010estatisticas111111\/relatorios1\/programa\u2010nacional\u2010para\u2010a\u2010infecao\u2010vih\u2010sida\u2010e\u2010tuberculose\u20102017\u2010pdf.aspx(accessed 22 February 2021)."},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a017871"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-3775-z"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rppnen.2017.11.003"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.2217\/fvl.12.123"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2004.00758.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1086\/424851"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04639-0"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034186"}],"container-title":["HIV Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hiv.13119","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/hiv.13119","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hiv.13119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T19:42:36Z","timestamp":1693338156000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hiv.13119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,17]]},"references-count":11,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1111\/hiv.13119"],"URL":"https:\/\/doi.org\/10.1111\/hiv.13119","archive":["Portico"],"relation":{},"ISSN":["1464-2662","1468-1293"],"issn-type":[{"value":"1464-2662","type":"print"},{"value":"1468-1293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,17]]},"assertion":[{"value":"2020-12-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}