{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T04:18:27Z","timestamp":1779250707285,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T00:00:00Z","timestamp":1647302400000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002865","name":"Chongqing Science and Technology Commission","doi-asserted-by":"publisher","award":["cxtc2019jscx\u2010msxmX0120"],"award-info":[{"award-number":["cxtc2019jscx\u2010msxmX0120"]}],"id":[{"id":"10.13039\/501100002865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>In this study, the distribution of nontuberculous mycobacteria (NTM) strains in patients with and without HIV\/AIDS in Chongqing, China was evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study was performed in January\u2013December 2020 at Chongqing Public Health Medical Center. NTM strains were assessed by a multi locus phylogenetic analysis. The distribution of NTM strains in HIV\/AIDS and non\u2010HIV\/AIDS groups was compared. CD4+ cell counts, imaging changes, and characteristics of mycobacterial species were determined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 324 patients with NTM infection (50 patients with HIV\/AIDS and 274 patients without HIV\/AIDS) were included. The most common etiological agent was <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>abscessus<\/jats:italic> (29%), followed by <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>paraintracellulare<\/jats:italic> (12%) and\u00a0<jats:italic>M<\/jats:italic>.\u00a0<jats:italic>colombiense<\/jats:italic> (11%). Predominant NTM species were <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>avium<\/jats:italic> (26%), <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>colombiense<\/jats:italic> (24%), and <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>kansasii<\/jats:italic> (18%) in patients with HIV\/AIDS and were\u00a0<jats:italic>M<\/jats:italic>.\u00a0<jats:italic>abscessus<\/jats:italic> (32%), <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>paraintracellulare<\/jats:italic> (13%), <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>fortuitum<\/jats:italic> (10%), and <jats:italic>M<\/jats:italic>. <jats:italic>intracellulare<\/jats:italic> (10%) in patients without HIV\/AIDS. For a CD4+ cell count of &lt;200\/\u03bcl, the predominant species were <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>avium<\/jats:italic>in the HIV\/AIDS group and <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>abscessus<\/jats:italic> in the non\u2010HIV\/AIDS group. With respect to radiologic characteristics, different NTM strains were associated with distinct imaging manifestations; for example, <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>marseillense<\/jats:italic>, <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>kansasii<\/jats:italic>, and <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>parasenchytosis<\/jats:italic> were more likely to induce cavities. Imaging cavities, bronchiectasis, and acinar\u2010like changes were more common in the non\u2010HIV\/AIDS groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The infection rates of HIV and NTM in Chongqing are high, while <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>abscessus<\/jats:italic>, <jats:italic>M<\/jats:italic>.<jats:italic>\u00a0paraintracellulare<\/jats:italic>, and <jats:italic>M<\/jats:italic>.\u00a0<jats:italic>colombiense<\/jats:italic> are the main pathogens causing NTM diseases in Chongqing, and NTM strains differed significantly between patients with and without HIV\/AIDS. Monitoring these indicators can help develop prevention strategies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.13249","type":"journal-article","created":{"date-parts":[[2022,3,16]],"date-time":"2022-03-16T01:39:48Z","timestamp":1647394788000},"page":"54-63","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Distribution of nontuberculous mycobacteria in patients with and without HIV\/AIDS in Chongqing"],"prefix":"10.1111","volume":"23","author":[{"given":"Jingmin","family":"Nie","sequence":"first","affiliation":[{"name":"Chongqing Public Health Medical Center  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xizi","family":"Deng","sequence":"additional","affiliation":[{"name":"Guangzhou Eighth People's Hospital Guangzhou Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingling","family":"Zeng","sequence":"additional","affiliation":[{"name":"Chongqing Public Health Medical Center  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Du","sequence":"additional","affiliation":[{"name":"Chongqing Public Health Medical Center  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaokai","family":"Chen","sequence":"additional","affiliation":[{"name":"Chongqing Public Health Medical Center  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengyu","family":"Hu","sequence":"additional","affiliation":[{"name":"Guangzhou Eighth People's Hospital Guangzhou Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,15]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"918","article-title":"Chinese medical association; 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