{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:58:50Z","timestamp":1790812730652,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T00:00:00Z","timestamp":1645747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although the prevalence and mortality of hepatitis is high in the Asia\u2010Pacific region, few studies are available on the diagnosis, treatment, and cure rates for viral hepatitis among people living with HIV in this area. This study aims to report the cascade of care (CoC) for hepatitis B (HBV) and C (HCV) among people living with HIV receiving combined antiretroviral therapy (ART).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients enrolled in the TREAT Asia HIV Observational Database Low Intensity Transfer (TAHOD\u2010LITE) cohort, on ART, and with follow\u2010up data from 2010 to 2019 were included. Patients were determined as positive for HCV or HBV co\u2010infection if they ever tested positive for HCV antibody (anti\u2010HCV) or HBV surface antigen (HBsAg), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 39% (8612\/22\u00a0340) of the adult HIV cohort had undergone HBsAg testing, with 8% (672\/8612) testing positive. HBV CoC demonstrated that 71% (474\/672) of those with HBsAg positive results initiated treatment, 67% (318\/474) of those on treatment had HBV DNA testing to evaluate treatment progression, and 18% (58\/318) of those tested reached viral suppression.<\/jats:p><jats:p>Of the cohort, 37% (8231\/22\u00a0340) had anti\u2010HCV testing, of whom 10% (779\/8231) tested positive. The HCV CoC showed that 68% (526\/779) of those with positive anti\u2010HCV tests had HCV RNA tests, of whom 51% (267\/526) had detectable HCV RNA. Among those with detectable HCV RNA, 65% (174\/267) initiated HCV treatment. Of the 40% (69\/174) who initiated HCV treatment, 90% (62\/69) reached sustained virological response.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings identified less frequent testing in the healthcare system and limited access to treatment as gaps in the CoC for viral hepatitis. More routine HCV RNA and HBV DNA testing is required for patients with positive screening tests to identify those in need of treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.13280","type":"journal-article","created":{"date-parts":[[2022,2,26]],"date-time":"2022-02-26T07:53:16Z","timestamp":1645861996000},"page":"959-968","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Viral hepatitis and the cascade of care among people living with HIV in the Asia\u2010Pacific"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4014-3570","authenticated-orcid":false,"given":"Dhanushi","family":"Rupasinghe","sequence":"first","affiliation":[{"name":"The Kirby Institute UNSW Sydney  Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2775-3315","authenticated-orcid":false,"given":"Jun 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