{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T19:24:50Z","timestamp":1768073090296,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,7,20]],"date-time":"2022-07-20T00:00:00Z","timestamp":1658275200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>After pre\u2010exposure prophylaxis (PrEP) was introduced, rates of sexually transmitted infections (STIs) increased among PrEP users. However, data on STI trends in people living with HIV since then are limited. Since September 2019, PrEP has been covered by statutory German health insurance (SHI) in vulnerable groups. This study aimed to determine whether this coverage of PrEP costs affected STI rates in people living with HIV (specifically, men who have sex with men).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients of the HIVCENTER Frankfurt diagnosed with at least one STI within the observation period were retrospectively enrolled in the study. STIs included infection with <jats:italic>Treponema pallidum<\/jats:italic>, <jats:italic>Chlamydia trachomatis<\/jats:italic>, <jats:italic>Neisseria gonorrhoeae<\/jats:italic>, and\/or <jats:italic>Trichomonas vaginalis<\/jats:italic>. The observation period covered 1\u2009year before and 1\u2009year after the coverage of PrEP costs by German SHI. Data were collected from outpatient clinic records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 143 patients were enrolled in the study. The observation period was September 2018 to August 2019 for group 1 (<jats:italic>n<\/jats:italic>\u00a0=\u200973) and September 2019 to August 2020 for group 2 (<jats:italic>n<\/jats:italic>\u00a0=\u200970). The most frequent STIs were syphilis and infections due to chlamydia, gonococci, and trichomonads, in descending order. Infections with <jats:italic>T. pallidum<\/jats:italic> occurred more often in group 2 than in group 1 (60.0% vs. 50.7%; <jats:italic>p<\/jats:italic>\u00a0=\u20090.253) as did chlamydia (37.1% vs. 28.8%; <jats:italic>p<\/jats:italic>\u00a0=\u20090.286).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A tendency for an increased ratio of STIs in people living with HIV was observed after the introduction of PrEP coverage by German SHI. STIs should be discussed intensively with people living with HIV, since the communities of PrEP users and people living with HIV overlap, and changes in risk behaviour might influence both groups.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.13353","type":"journal-article","created":{"date-parts":[[2022,7,21]],"date-time":"2022-07-21T04:48:30Z","timestamp":1658378910000},"page":"163-169","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Sexually transmitted diseases in people living with <scp>HIV<\/scp> after implementation of cost coverage of <scp>HIV<\/scp> pre\u2010exposure prophylaxis by statutory health insurance in Germany"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6828-4116","authenticated-orcid":false,"given":"Gundolf","family":"Schuettfort","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Infectious Diseases University Hospital Frankfurt, Goethe University  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Groh","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infectious Diseases University Hospital Frankfurt, Goethe University  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerrit","family":"Kann","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infectious Diseases University Hospital Frankfurt, Goethe University  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annette","family":"Haberl","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infectious Diseases University Hospital Frankfurt, Goethe University  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Herrmann","sequence":"additional","affiliation":[{"name":"Institute of Biostatistics and Mathematical Modelling Goethe University Frankfurt  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nils","family":"Wetzstein","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infectious Diseases University Hospital Frankfurt, Goethe University  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Johanna Gobertina Tetuanui","family":"Vehreschild","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infectious Diseases University Hospital Frankfurt, Goethe University  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Stephan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Infectious Diseases University Hospital Frankfurt, Goethe University  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,20]]},"reference":[{"key":"e_1_2_20_2_1","unstructured":"Deutscher \u00c4rzteverlag GmbH Redaktion Deutsches \u00c4rzteblatt.Coronapandemie senkt Nachfrage nach HIV\u2010Pr\u00e4expositionsprophylaxe. 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