{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T15:07:05Z","timestamp":1793113625208,"version":"4.5.0"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T00:00:00Z","timestamp":1665619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007553","name":"Aids Fonds","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005564","name":"Gilead Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007192","name":"Rijksinstituut voor Volksgezondheid en Milieu","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007192","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We studied the effects of restrictions related to the severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102; coronavirus disease 2019 [COVID\u201019]) pandemic on the use of sexual healthcare and pre\u2010exposure prophylaxis (PrEP) and on the incidence of sexually transmitted infections (STIs) among men who have sex with men (MSM) in a prospective, open\u2010label PrEP demonstration study (AMPrEP) in Amsterdam, the Netherlands.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrieved data from 2019 to 2020 for participants with one or more study visit in 2019 (n\u00a0=\u00a0305) and from two COVID\u201019 questionnaires (2020: n\u00a0=\u00a0203; 2021: n\u00a0=\u00a0160). Analyses were stratified for three periods of pandemic\u2010related restrictions (first: 15 March 2020\u201315 June 2020; second: 16 June 2020\u201315 September 2020; third: 16 September 2020\u201331 December 2020 or 1 April 2021 for the COVID\u201019 questionnaire). Endpoints included returning for care during the pandemic, PrEP use (increased\/unchanged vs. deceased\/stopped, relative to 2019), and any STI\/HIV. We modelled determinants of care and PrEP use via multivariable logistic regression and STI incidence using piecewise Poisson regression, comparing the 2020 and 2019 periods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 305 MSM included in the analysis, 72.8% returned for care during the pandemic, and this was significantly more likely among daily (vs. event\u2010driven) PrEP users (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Increased\/unchanged PrEP use ranged from 55.2% to 58.1% across the three pandemic periods and was more likely among those reporting chemsex in the first (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.001) and third (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.020) periods and among those reporting an increased\/unchanged number of sex partners during the second period (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.010). STI incidence was significantly lower in 2020 than in 2019 during the first period (incidence rate ratio [IRR] 0.43; 95% confidence interval [CI] 0.28\u20130.68) and not significantly different during the second (IRR 1.38; 95% CI 0.95\u20132.00) and third (IRR 1.42; 95% CI 0.86\u20132.33) periods. No HIV was diagnosed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>COVID\u201019\u2010related restrictions coincided with reduced care and PrEP use. Changes in STI incidence suggest delayed diagnoses. Ways to ensure continued access to sexual healthcare during restrictions are needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.13374","type":"journal-article","created":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T03:51:05Z","timestamp":1665633065000},"page":"212-223","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["The impact of <scp>COVID<\/scp>\u201019\u2010related restrictions in 2020 on sexual healthcare use, pre\u2010exposure prophylaxis use, and sexually transmitted infection incidence among men who have sex with men in Amsterdam, the Netherlands"],"prefix":"10.1111","volume":"24","author":[{"given":"Feline","family":"de la Court","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Public Health Service of Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Boyd","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service of Amsterdam  Amsterdam the Netherlands"},{"name":"stichting hiv monitoring  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liza","family":"Coyer","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service of Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"van den Elshout","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service of Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry J. C.","family":"de Vries","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service of Amsterdam  Amsterdam the Netherlands"},{"name":"Amsterdam UMC location University of Amsterdam Department of Dermatology  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Matser","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service of Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elske","family":"Hoornenborg","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service of Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Prins","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service of Amsterdam  Amsterdam the Netherlands"},{"name":"Amsterdam UMC location University of Amsterdam Department of Infectious Diseases, Amsterdam institute for Infection &amp; Immunity (AII)  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the HIV Transmission Elimination AMsterdam, H\u2010TEAM) Consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30120-1"},{"key":"e_1_2_10_3_1","unstructured":"Rijksoverheid. 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