{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:30:48Z","timestamp":1761921048634,"version":"3.40.5"},"reference-count":45,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We aimed to describe clinical policies for the management of people with HIV\/hepatitis C virus (HCV) coinfection and to audit routine monitoring and assessment of people with HIV\/HCV coinfection attending UK HIV care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a clinic survey and retrospective case\u2010note review. HIV clinics in the UK participated in the audit from May to July 2021 by completing an online questionnaire regarding their clinic's policies for the management of people with HIV\/HCV coinfection, and by contributing to a case\u2010note review of people living with HIV with detectable HCV RNA who were under the care of their service.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety\u2010five clinics participated in the clinic survey; of these, 15 (15.8%) were regional specialist centres, 19 (20.0%) were HIV services with their own coinfection clinics, 40 (42.1%) were HIV services that referred coinfected individuals to a local hepatology service and 20 (21.1%) were HIV services that referred to a regional specialist centre. Eighty\u2010one clinics provided full caseload estimates; of the approximately 3951 people with a history of HIV\/HCV coinfection accessing their clinics, only 4.9% were believed to have detectable HCV RNA, 3.15% of whom were already receiving or approved for direct\u2010acting antiviral (DAA) treatment. In total, 29 (30.5%) of the clinics reported an impact of COVID\u201019 on coinfection care, including delays or reductions in the frequency of services, monitoring, treatment initiation and appointments, and changes to the way that treatment was dispensed. Case\u2010note reviews were provided for 283 people with detectable HCV RNA from 74 clinics (median age 42\u2009years, 74.6% male, 56.2% HCV genotype 1, 22.3% HCV genotype 3). Overall, 56% had not received treatment for HCV, primarily due to lack of engagement in care (54.7%) and\/or being uncontactable (16.4%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings show that the small number of people with HIV with detectable HCV RNA in the UK should mean that it is possible to achieve HCV micro\u2010elimination. However, more work is needed to improve engagement in care for those who are untreated for HCV.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.13417","type":"journal-article","created":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T09:36:54Z","timestamp":1664444214000},"page":"471-479","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The British <scp>HIV<\/scp> Association national clinical audit 2021: Management of <scp>HIV<\/scp> and hepatitis C coinfection"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4548-6820","authenticated-orcid":false,"given":"Reynie P.","family":"Raya","sequence":"first","affiliation":[{"name":"National Institute for Health Research (NIHR) Health Protection Research Unit (HPRU) in Blood Borne and Sexually Transmitted Infections at UCL Royal Free Campus  London UK"},{"name":"Centre for Clinical Research, Epidemiology, Modelling and Evaluation Institute for Global Health, UCL, Royal Free Campus  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilary","family":"Curtis","sequence":"additional","affiliation":[{"name":"British HIV Association (BHIVA)  Letchworth UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0472-698X","authenticated-orcid":false,"given":"Ranjababu","family":"Kulasegaram","sequence":"additional","affiliation":[{"name":"Department of Sexual Health St Thomas Hospital  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham S.","family":"Cooke","sequence":"additional","affiliation":[{"name":"British HIV Association (BHIVA)  Letchworth UK"},{"name":"Department of Infectious Disease, Imperial College London St Mary's Campus  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona","family":"Burns","sequence":"additional","affiliation":[{"name":"Centre for Clinical Research, Epidemiology, Modelling and Evaluation Institute for Global Health, UCL, Royal Free Campus  London UK"},{"name":"Royal Free London NHS Foundation Trust  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Chadwick","sequence":"additional","affiliation":[{"name":"British HIV Association (BHIVA)  Letchworth UK"},{"name":"Department of Infectious Diseases, South Tees Hospitals NHS Foundation Trust Centre for Clinical Infections  Middlesbrough UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5173-2760","authenticated-orcid":false,"given":"Caroline A.","family":"Sabin","sequence":"additional","affiliation":[{"name":"National Institute for Health Research (NIHR) Health Protection Research Unit (HPRU) in Blood Borne and Sexually Transmitted Infections at UCL Royal Free Campus  London UK"},{"name":"Centre for Clinical Research, Epidemiology, Modelling and Evaluation Institute for Global Health, UCL, Royal Free Campus  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the BHIVA Audit and Standards Sub\u2010committee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.12662"},{"volume-title":"Viral Hepatitis and HIV Co\u2010Infection in the UK Collaborative HIV Cohort (UK CHIC) Study: UCL","year":"2015","author":"Thornton AC","key":"e_1_2_11_3_1"},{"key":"e_1_2_11_4_1","unstructured":"PHE.HIV in the United Kingdom: Towards Zero HIV transmissions by 2030.2019."},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0b013e32834bd257"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040842"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13626"},{"volume-title":"Global Health Sector Strategy on Viral Hepatitis 2016\u20132021. 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