{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T11:48:14Z","timestamp":1771933694647,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T00:00:00Z","timestamp":1696204800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003107","name":"Bundesministerium f\u00fcr Gesundheit","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003107","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Viral hepatitis co\u2010infection among people living with HIV is known to accelerate the progression of liver disease and AIDS. An increased prevalence and incidence of hepatitis B virus (HBV) infection among people living with HIV demands continuous monitoring to adapt targeted prevention strategies to reach the global goals of eliminating viral hepatitis as a public health threat.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We determined the prevalence and incidence of HBV for the years 1996\u20132019 from yearly blood sample testing and questionnaire reports among people living with HIV belonging to a nationwide, multicentre observational, prospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among this study population of 3479 participants, the majority (87%) indicated that being men who have sex with men (MSM) was their likely HIV transmission route; 51% were recruited from Berlin. HBV prevalence for acute\/chronic and resolved infections decreased from 4.1% and 45% in 1996\u20131999 to 1.3% and 16% in 2019, respectively. Simultaneously, participants with a serological status indicating HBV vaccination increased from 25% in 1996\u20131999 to 69% in 2019. Among vaccinated participants with relevant information (<jats:italic>n<\/jats:italic>\u2009=\u20091135), 38% received their first HBV vaccination after HIV infection. The HBV incidence rate in 565 eligible participants decreased from 6.9\/100 person\u2010years in 2004\u20132007 to 0.45\/100 person\u2010years in 2015.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Increasing vaccination coverage because of a general HBV vaccination recommendation and catch\u2010up vaccination efforts among risk groups decreased HBV infection prevalence over time among this study population of people living with HIV, primarily MSM and from Berlin. Despite this success, the prevalence and incidence of HBV remains higher than in the general population in Germany. This emphasizes the need for continued HBV prevention by promoting HBV vaccination and HBV screening at regular intervals based on the individual risk behaviour.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.13554","type":"journal-article","created":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T05:55:37Z","timestamp":1696312537000},"page":"201-211","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Increasing hepatitis B vaccination coverage and decreasing hepatitis B co\u2010infection prevalence among people with <scp>HIV<\/scp>\u20101 in Germany, 1996\u20132019. Results from a cohort study primarily in men who have sex with men"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9638-0885","authenticated-orcid":false,"given":"A.","family":"Krings","sequence":"first","affiliation":[{"name":"Department of Infectious Disease Epidemiology Robert Koch Institute  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Epidemiology Robert Koch Institute  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Kollan","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Epidemiology Robert Koch Institute  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Meixenberger","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Robert Koch Institute  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Bannert","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Robert Koch Institute  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"M\u00fcnstermann","sequence":"additional","affiliation":[{"name":"MVZ Labor Krone GbR  Bad Salzuflen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Tiemann","sequence":"additional","affiliation":[{"name":"MVZ Labor Krone GbR  Bad Salzuflen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Bremer","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Epidemiology Robert Koch Institute  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Gunsenheimer\u2010Bartmeyer","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Epidemiology Robert Koch Institute  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the German HIV\u20101 Seroconverter Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,10,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30579-7"},{"key":"e_1_2_10_3_1","volume-title":"WHO Global Health Sector Strategy on Viral Hepatitis","author":"World Health Organization","year":"2016"},{"issue":"31","key":"e_1_2_10_4_1","first-page":"3","article-title":"Zur Situation bei wichtigen Infektionskrankheiten in Deutschland\u2014Hepatitis C im Jahr 2019","volume":"30","author":"Zimmermann R","year":"2020","journal-title":"Epidemiologisches Bulletin"},{"issue":"31","key":"e_1_2_10_5_1","first-page":"3","article-title":"Virushepatitis B und D im Jahr 2019","volume":"30","author":"Dudareva S","year":"2020","journal-title":"Epidemiologisches Bulletin"},{"key":"e_1_2_10_6_1","unstructured":"German Federal Ministry of Health.Integrated Strategy for HIV Hepatitis B and C and Other Sexually Transmitted Infections. 2016."},{"key":"e_1_2_10_7_1","first-page":"371","article-title":"Wissenschaftliche Begr\u00fcndung f\u00fcr die \u00c4nderung der Empfehlung zur Impfung gegen Hepatitis B","volume":"36","author":"St\u00e4ndige Impfkommission (STIKO)","year":"2013","journal-title":"Epidemiologisches Bulletin"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/163.5.1138"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2015.09.011"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000180"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068152"},{"key":"e_1_2_10_12_1","volume-title":"Hepathology\u2014A Clinical Textbook","author":"Mauss S","year":"2017"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0142515"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2020.00424"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2007.00504.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012718"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0095956"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0209605"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.13670"},{"key":"e_1_2_10_20_1","first-page":"3","article-title":"Sch\u00e4tzung der Zahl der HIV\u2010Neuinfektionen und der Gesamtzahl von Menschen mit HIV in Deutschland, Stand Ende 2019","volume":"48","author":"an der Heiden M","year":"2020","journal-title":"Epidemiologisches Bulletin"},{"key":"e_1_2_10_21_1","unstructured":"Deutsche AIDS\u2010Gesellschaft e.V. 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