{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T04:59:01Z","timestamp":1777611541880,"version":"3.51.4"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T00:00:00Z","timestamp":1705622400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although HIV\u2010related deaths among people with HIV have dramatically decreased, deaths from other medical conditions and non\u2010medical events have increased. The location of death among people with HIV remains underreported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We reviewed the deaths, causes of death, and reported location of death (i.e. within or outside of medical settings) of all people with HIV with the Southern Alberta Cohort, Calgary, Canada, between 1 January 2010 and 1 January 2022.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective longitudinal cohort study reviewing all deaths within a comprehensive geographically defined HIV cohort over 11\u2009years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Deaths from HIV\u2010related causes decreased from 52% of all deaths in 2010 to 14% in 2021. In 2021, non\u2010HIV medical deaths increased from 38% to 44%, and non\u2010medical deaths (e.g. violence, suicide, drug overdose) increased from 0.5% to 39%. Of non\u2010medical deaths, 67% resulted from substance use\/overdose. Overall, deaths in any medical setting decreased from 91% in 2010 to 39% in 2021; 61% of all deaths occurred in a medical setting (e.g. hospital\/emergency department or supported\/long\u2010term\/hospice care), 27% in a residence, and 9% in the community.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The shifting causes of death (i.e. fewer HIV\u2010related deaths, more overdose deaths) and location of death (i.e. fewer in medical settings, more at home\/in the community) requires close monitoring so future resources can be matched to predicted patient needs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.13610","type":"journal-article","created":{"date-parts":[[2024,1,20]],"date-time":"2024-01-20T06:33:48Z","timestamp":1705732428000},"page":"608-613","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The changing landscape of both causes and locations of death in a regional <scp>HIV<\/scp> population 2010\u20132021"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4842-2846","authenticated-orcid":false,"given":"Hartmut B.","family":"Krentz","sequence":"first","affiliation":[{"name":"Department of Medicine University of Calgary  Calgary Alberta Canada"},{"name":"Southern Alberta Clinic Alberta Health Services  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raynell","family":"Lang","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Calgary  Calgary Alberta Canada"},{"name":"Southern Alberta Clinic Alberta Health Services  Calgary Alberta Canada"},{"name":"Department of Community Health Sciences University of Calgary  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"McMillan","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Calgary  Calgary Alberta Canada"},{"name":"Southern Alberta Clinic Alberta Health Services  Calgary Alberta Canada"},{"name":"Department of Community Health Sciences University of Calgary  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meagan","family":"Ody","sequence":"additional","affiliation":[{"name":"Southern Alberta Clinic Alberta Health Services  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. John","family":"Gill","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Calgary  Calgary Alberta Canada"},{"name":"Southern Alberta Clinic Alberta Health Services  Calgary Alberta Canada"},{"name":"Department of Microbiology, Immunology &amp; Infectious Diseases University of Calgary  Calgary Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3283324283"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.puhe.2016.05.004"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.12617"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)03201-2"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.7861\/clinmedicine.8-3-250"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2005.00271.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6946a1"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00391-3"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2022.2081152"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e31821b5332"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwz232"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000003105"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir627"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.19775"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(23)00178-0"},{"key":"e_1_2_9_17_1","unstructured":"Govt of Alberta.https:\/\/open.alberta.ca\/opendata\/life\u2010expectancy\u2010in\u2010Alberta\u2010at\u2010birth\u2010and\u2010age\u201065.caAccessed 16 October 2022."},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000002545"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/gpsych\u20102020\u2010100247"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2020.108003"},{"key":"e_1_2_9_21_1","unstructured":"Alberta Substance use surveillance system.2023https:\/\/healthanalytics.alberta.ca\/SASVisualAnalytesAccessed: 03 December 2023."},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0000000000000659"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(21)00022-9"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1911892"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001478"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2020.0051"}],"container-title":["HIV Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hiv.13610","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T05:46:53Z","timestamp":1715147213000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hiv.13610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,19]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1111\/hiv.13610"],"URL":"https:\/\/doi.org\/10.1111\/hiv.13610","archive":["Portico"],"relation":{},"ISSN":["1464-2662","1468-1293"],"issn-type":[{"value":"1464-2662","type":"print"},{"value":"1468-1293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,19]]},"assertion":[{"value":"2023-10-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}