{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T21:07:54Z","timestamp":1769720874840,"version":"3.49.0"},"reference-count":18,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2024,9]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>The 2022 mpox outbreak continues, and while progress has been made in prevention strategies and potential treatment options, data on late sequelae following mpox are scarce.<\/jats:p><\/jats:sec>Objective<\/jats:title>This analysis aimed to assess the incidence of scar formation in individuals affected by the 2022 mpox outbreak.<\/jats:p><\/jats:sec>Methods<\/jats:title>All individuals diagnosed with mpox at the Department of Dermatology at the Medical University of Vienna in 2022 were included in this analysis. Follow\u2010up data were collected throughout November 2023. \u2018Scar formation\u2019 was defined as having at least one scar at the former active mpox lesions.<\/jats:p><\/jats:sec>Results<\/jats:title>At our clinic, 28 cases of mpox presented between June 2022 and October 2022 and exclusively occurred in men who have sex with men (100%, 28\/28), of whom 46% (13\/28) were living with HIV, and 32% (9\/28) were using pre\u2010exposure prophylaxis (PrEP). Secondary bacterial infection of mpox lesions was suspected in six individuals, and all received systemic antibiotics. Overall, 26 were followed up in November 2023 after a median time of 15\u2009months, and scar formations were found in 43% of cases.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Our data provide insights into the late yet cumulating disease burden caused by the 2022 mpox outbreak. Highly effective prevention strategies are warranted to overcome the mpox epidemic and its potential late sequelae.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.13678","type":"journal-article","created":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T04:55:11Z","timestamp":1717131311000},"page":"1091-1096","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Scars are frequently found as late sequelae in individuals affected by the 2022 mpox<\/scp> outbreak"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1807-8258","authenticated-orcid":false,"given":"David","family":"Chromy","sequence":"first","affiliation":[{"name":"Department of Dermatology Medical University of Vienna Vienna Austria"},{"name":"Department of Dermatology and Venereology University Hospital Essen, University Duisburg\u2010Essen Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4052-1092","authenticated-orcid":false,"given":"Nikolaus","family":"Urban","sequence":"additional","affiliation":[{"name":"Department of Surgery, Klinik Favoriten Vienna Healthcare Group Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0155-1176","authenticated-orcid":false,"given":"Wolfgang Michael","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Medical University of Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Kreuter","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology, Helios St. Elisabeth Hospital Oberhausen University of Witten\/Herdecke Oberhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2157-0382","authenticated-orcid":false,"given":"Robert","family":"Strassl","sequence":"additional","affiliation":[{"name":"Division of Clinical Virology, Department of Laboratory Medicine Medical University Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0665-5414","authenticated-orcid":false,"given":"Katharina","family":"Grabmeier\u2010Pfistershammer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Medical University of Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2207323"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02542-x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciac960"},{"key":"e_1_2_10_5_1","unstructured":"World Health Organisation.2022\u201323 Mpox outbreak: global trends.2023https:\/\/worldhealthorg.shinyapps.io\/mpx_global\/[Accessed 07 Jan 2024]"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2023.11.025"},{"key":"e_1_2_10_7_1","first-page":"ofad552","article-title":"Clinical characteristics and outcomes of patients with Mpox who received Tecovirimat in a new York City health system. Open forum","volume":"10","author":"Vo C","year":"2023","journal-title":"Infect Dis"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2019.03.001"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2220415120"},{"issue":"11","key":"e_1_2_10_10_1","first-page":"ofad552","article-title":"A global systematic evidence review with meta\u2010analysis of the epidemiological characteristics of the 2022 Mpox outbreaks","volume":"10","author":"Okoli GN","year":"2023","journal-title":"Infection"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)00273-8"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2022.12.035"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.onehlt.2023.100523"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/088532829100500405"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-024-09191-6"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.2340\/actadv.v103.6485"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113250"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2215201"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7236a4"}],"container-title":["HIV Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hiv.13678","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T09:29:56Z","timestamp":1732008596000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hiv.13678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,30]]},"references-count":18,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1111\/hiv.13678"],"URL":"https:\/\/doi.org\/10.1111\/hiv.13678","archive":["Portico"],"relation":{},"ISSN":["1464-2662","1468-1293"],"issn-type":[{"value":"1464-2662","type":"print"},{"value":"1468-1293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,30]]},"assertion":[{"value":"2024-04-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}