{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T22:59:43Z","timestamp":1789340383834,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>This study aimed to describe the prevalence of high\u2010risk human papillomavirus (HR\u2010HPV) types in the anal canal in a cohort of people living with HIV (PLWHIV) with a history of malignancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Referral tertiary care hospital for adult patients with cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed data of patients from the AIDS Cancer Clinic on antiretroviral therapy in chronic control who were consecutively referred for high\u2010resolution anoscopy (HRA), where they underwent anal evaluation, collection of specimens for anal cytology and anal human papillomavirus (HPV) followed by HRA with directed biopsy if needed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 155 patients were included; 149 (96.1%) were men, all of them men who have sex with men (MSM); the median age was 39 (IQR 32\u201047) years; 105 (67.7%) with Kaposi sarcoma, 40 (25.8%) with non\u2010Hodgkin lymphoma and 10 (6.4%) with other neoplasms; only 7 (4.5%) had active cancer. The prevalence of HR\u2010HPV infection was 89% (<jats:italic>n<\/jats:italic>=138) (95% CI 83\u201393) with at least one HR\u2010HPV infection, and 62% (96) had coinfection with at least two types; the median HR\u2010HPV types of coinfection were 3 (IQR 2\u20134). The number of patients infected with HPV 16 was 64 (41.3%, 95% CI 33.8\u201349.3), HPV 18 was 74 (47.7%, 95% CI 39.9\u201355.7) and with both 35 (22.6%). Some 59 patients (38%) had high\u2010grade squamous intraepithelial lesions (HSIL) and 49 (31.6%) had low\u2010grade squamous intraepithelial lesions (LSIL). The prevalence of HR\u2010HPV and HSIL among patients aged \u226435 and &gt;35\u2009years was the same.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this cohort of PLWHIV with a history of malignancy we found a high prevalence of HR\u2010HPV 16 and 18 and anal HSIL, even in persons aged \u226435\u2009years. These data highlight the importance of anal cancer screening in PLWHIV and history of malignancy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hiv.13684","type":"journal-article","created":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T04:49:28Z","timestamp":1718945368000},"page":"1145-1153","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence of anal high\u2010risk human papillomavirus (<scp>HR<\/scp>\u2010<scp>HPV)<\/scp> types in people living with <scp>HIV<\/scp> and a history of cancer"],"prefix":"10.1111","volume":"25","author":[{"given":"Salim A.","family":"Barquet\u2010Mu\u00f1oz","sequence":"first","affiliation":[{"name":"Dysplasia Department Instituto Nacional de Cancerolog\u00eda  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana A.","family":"L\u00f3pez\u2010Morales","sequence":"additional","affiliation":[{"name":"Laboratory of Virus and Cancer Unidad de Investigaci\u00f3n Biom\u00e9dica en C\u00e1ncer, Instituto de Investigaciones Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico &amp; 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