{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T02:55:43Z","timestamp":1790477743000,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T00:00:00Z","timestamp":1737417600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI20CIII\/00027"],"award-info":[{"award-number":["PI20CIII\/00027"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We aimed to describe health\u2010related quality of life (HRQoL), overall and across its dimensions, identify associated factors, and assess changes over time among people with HIV (PWH) from the Spanish multicentre CoRIS cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We developed a mobile app to collect HRQoL data every 3\u2009months using the WHOQOL\u2010HIV\u2010BREF questionnaire (31 items across six domains), among PWH followed in CoRIS in 2021\u20132023. Factors associated with good\/very good global HRQoL and with domain\u2010specific mean scores were identified using multivariable logistic and linear regression, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 414 PWH (94.2% on antiretroviral treatment, 91.1% virally suppressed), 51.2% reported good\/very good HRQoL. Latin American migrants (adjusted OR: 0.60 [95% CI: 0.36; 1.00]), and participants with lower educational level (0.36 [0.21; 0.64]), a previous AIDS diagnosis (0.56 [0.29; 1.11]) and a history of non\u2010AIDS\u2010related cancers (0.40 [0.14; 1.14]) were less likely to report good\/very good global HRQoL. The most affected items included sexual satisfaction, forgiveness and blame, sleep and rest, and concerns about the future, with spirituality, religion and personal beliefs as the most affected domain. Latin American origin, lower educational level and shorter (&lt;2\u2009years) or longer (&gt;15\u2009years) time since HIV diagnosis were associated with poorer HRQoL in specific domains. No significant changes in HRQoL were observed after 12\u2009months except slightly higher scores in physical health.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Only half of PWH reported good\/very good global HRQoL. This highlights the need to develop targeted strategies to improve HRQoL among PWH, focusing on addressing the most affected dimensions and supporting the most vulnerable groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hiv.13762","type":"journal-article","created":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T06:30:44Z","timestamp":1737441044000},"page":"606-620","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Health\u2010related quality of life in people with\n                    <scp>HIV<\/scp>\n                    from the multicentre\n                    <scp>CoRIS<\/scp>\n                    cohort in Spain: Associated factors and short\u2010term changes over time"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5780-4462","authenticated-orcid":false,"given":"Rebeca","family":"Izquierdo","sequence":"first","affiliation":[{"name":"National Centre for Epidemiology Carlos III Health Institute  Madrid Spain"},{"name":"CIBERINFEC Carlos III Health Institute  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7016-716X","authenticated-orcid":false,"given":"In\u00e9s","family":"Su\u00e1rez\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"CIBERINFEC Carlos III Health Institute  Madrid Spain"},{"name":"Infectious Diseases Group, Department of Internal Medicine Infanta Sof\u00eda University Hospital, Infanta Sofia University Hospital and Henares University Hospital Foundation for Biomedical Research and Innovation (FIIB HUIS HHEN)  Madrid Spain"},{"name":"Department of Medicine European University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2799-0890","authenticated-orcid":false,"given":"Cristina","family":"Marco\u2010S\u00e1nchez","sequence":"additional","affiliation":[{"name":"National Centre for Epidemiology Carlos III Health Institute  Madrid Spain"},{"name":"CIBERINFEC Carlos III Health Institute  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leire","family":"P\u00e9rez\u2010Latorre","sequence":"additional","affiliation":[{"name":"CIBERINFEC Carlos III Health Institute  Madrid Spain"},{"name":"Department of Infectious Diseases Gregorio Mara\u00f1\u00f3n General University Hospital, Gregorio Mara\u00f1\u00f3n Institute of Health Research (IiSGM)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0887-8710","authenticated-orcid":false,"given":"Melchor","family":"Riera","sequence":"additional","affiliation":[{"name":"CIBERINFEC Carlos III Health Institute  Madrid Spain"},{"name":"Infectious Diseases Unit, Internal Medicine Department Son Espases University Hospital, Illes Balears Health Research Institute (IdISBa)  Palma de Mallorca 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