{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T08:58:43Z","timestamp":1774342723188,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T00:00:00Z","timestamp":1753833600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T00:00:00Z","timestamp":1753833600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100003896","name":"Henry M. 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All maintained their ART regimens for 96\u2009weeks, with assessments at weeks 0, 24, 48, 72 and 96. Longitudinal changes were compared using linear mixed models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At week 0, the two groups were similar in age, sex, levels of plasma HIV RNA, CD4+ and CD8+ T\u2010cell counts and CD4\/CD8 ratios, along with levels of total cholesterol (TC), low\u2010density lipoprotein (LDL) and DBP. However, DTG\/ABC\/3TC users had higher BMI and lower SBP than EFV\/TDF\/FTC users (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). After 96\u2009weeks, DTG\/ABC\/3TC users demonstrated greater increases in BMI, SBP, TC and LDL than EFV\/TDF\/FTC users in unadjusted and adjusted models corrected for age, sex and Fiebig staging (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), while their changes in DBP and high\u2010density lipoprotein did not differ.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In these young men initiating ART during AHI, DTG\/ABC\/3TC users exhibited greater increases in BMI, SBP, TC and LDL than EFV\/TDF\/FTC users by week 96. In addition to body weight changes, clinicians should remain vigilant regarding blood pressure and cholesterol changes following ART initiation, especially in those with pre\u2010existing cardiovascular risk factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hiv.70085","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T02:49:49Z","timestamp":1753930189000},"page":"1619-1625","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Blood pressure and metabolic outcomes after efavirenz\u2010 or dolutegravir\u2010based therapy started in acute\n                    <scp>HIV<\/scp>\n                    infection"],"prefix":"10.1111","volume":"26","author":[{"given":"Phillip","family":"Chan","sequence":"first","affiliation":[{"name":"Department of Neurology Yale University School of Medicine  New Haven Connecticut USA"},{"name":"Yale Center for Brain and Mind Health Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Moreland","sequence":"additional","affiliation":[{"name":"Military HIV Research Program Walter Reed Army Institute of Research  Silver Spring Maryland USA"},{"name":"Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc  Bethesda Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Sacdalan","sequence":"additional","affiliation":[{"name":"SEARCH Research Foundation  Bangkok Thailand"},{"name":"Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donn J.","family":"Colby","sequence":"additional","affiliation":[{"name":"Military HIV Research Program Walter Reed Army Institute of Research  Silver Spring Maryland USA"},{"name":"Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc  Bethesda Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferron","family":"Ocampo","sequence":"additional","affiliation":[{"name":"SEARCH Research Foundation  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pathariya","family":"Promsena","sequence":"additional","affiliation":[{"name":"SEARCH Research Foundation  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somchai","family":"Sriplienchan","sequence":"additional","affiliation":[{"name":"SEARCH Research Foundation  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jarawee","family":"Wattana","sequence":"additional","affiliation":[{"name":"SEARCH Research Foundation  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jintana","family":"Intasan","sequence":"additional","affiliation":[{"name":"SEARCH Research Foundation  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nittaya","family":"Phanuphak","sequence":"additional","affiliation":[{"name":"Institute of HIV Research and Innovation (IHRI)  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandhya","family":"Vasan","sequence":"additional","affiliation":[{"name":"Military HIV Research Program Walter Reed Army Institute of Research  Silver Spring Maryland USA"},{"name":"Henry M. 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